Advanced SPR-Based Biosensors for Potential Use in Cancer Detection: A Theoretical Approach DOI Creative Commons
Talía Tene, Fabian Arias Arias, Darío Fernando Guamán Lozada

и другие.

Sensors, Год журнала: 2025, Номер 25(9), С. 2685 - 2685

Опубликована: Апрель 24, 2025

This study presents a numerical investigation of surface plasmon resonance (SPR) sensors based on multilayer configurations incorporating BK7, silver, silicon nitride (Si3N4), and black phosphorus (BP). Using the transfer matrix method, optical performance four architectures was evaluated under refractive index perturbations consistent with values reported in prior theoretical experimental studies. The sensor response characterized through metrics such as angular sensitivity, shift, full width at half maximum, attenuation, derived figures including detection accuracy limit detection. Parametric optimization performed for thickness each functional layer to enhance sensing performance. Among all configurations, those both Si3N4 BP demonstrated highest reaching up 394.46°/RIU. These enhancements were accompanied by increased attenuation spectral broadening, revealing trade-offs design. results, entirely modeling, provide comparative framework guiding SPR idealized conditions.

Язык: Английский

Advanced SPR-Based Biosensors for Potential Use in Cancer Detection: A Theoretical Approach DOI Creative Commons
Talía Tene, Fabian Arias Arias, Darío Fernando Guamán Lozada

и другие.

Sensors, Год журнала: 2025, Номер 25(9), С. 2685 - 2685

Опубликована: Апрель 24, 2025

This study presents a numerical investigation of surface plasmon resonance (SPR) sensors based on multilayer configurations incorporating BK7, silver, silicon nitride (Si3N4), and black phosphorus (BP). Using the transfer matrix method, optical performance four architectures was evaluated under refractive index perturbations consistent with values reported in prior theoretical experimental studies. The sensor response characterized through metrics such as angular sensitivity, shift, full width at half maximum, attenuation, derived figures including detection accuracy limit detection. Parametric optimization performed for thickness each functional layer to enhance sensing performance. Among all configurations, those both Si3N4 BP demonstrated highest reaching up 394.46°/RIU. These enhancements were accompanied by increased attenuation spectral broadening, revealing trade-offs design. results, entirely modeling, provide comparative framework guiding SPR idealized conditions.

Язык: Английский

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