Immunological Regulation of Gut-Tropic Immune Cells by Extracellular Vesicles DOI

Yasunari Matsuzaka,

Ryu Yashiro

Immunological Investigations, Год журнала: 2023, Номер 53(1), С. 40 - 69

Опубликована: Ноя. 21, 2023

The remarkable diversity of lymphocytes, essential components the immune system, serves as an ingenious mechanism for maximizing efficient utilization limited host defense resources. While cell adhesion molecules, notably in gut-tropic T cells, play a central role this mechanism, counterbalancing molecular details have remained elusive. Conversely, we've uncovered pathways enabling extracellular vesicles secreted by lymphocytes to reach gut's mucosal tissues, facilitating immunological regulation. This discovery sheds light on fine-tuning, offering insights into regulation mechanisms.

Язык: Английский

Immunological Regulation of Gut-Tropic Immune Cells by Extracellular Vesicles DOI

Yasunari Matsuzaka,

Ryu Yashiro

Immunological Investigations, Год журнала: 2023, Номер 53(1), С. 40 - 69

Опубликована: Ноя. 21, 2023

The remarkable diversity of lymphocytes, essential components the immune system, serves as an ingenious mechanism for maximizing efficient utilization limited host defense resources. While cell adhesion molecules, notably in gut-tropic T cells, play a central role this mechanism, counterbalancing molecular details have remained elusive. Conversely, we've uncovered pathways enabling extracellular vesicles secreted by lymphocytes to reach gut's mucosal tissues, facilitating immunological regulation. This discovery sheds light on fine-tuning, offering insights into regulation mechanisms.

Язык: Английский

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