Cited by Platycodin D ameliorates polycystic ovary syndrome-induced ovarian damage by upregulating CD44 to attenuate ferroptosis

Clinical manifestations of polycystic ovary syndrome DOI

Radmila Sparić,

Jelena Zlatar,

Luka Nikolić

и другие.

Medicinska istrazivanja, Год журнала: 2024, Номер 57(4), С. 93 - 102

Опубликована: Янв. 1, 2024

Polycystic ovary syndrome, commonly abbreviated as PCOS, the most common endocrine disorder in women of reproductive age, is a multifaceted disease characterized by various hormonal imbalances and great degree variation its clinical presentation. This, coupled with etiology pathogenesis being incompletely understood, results broad spectrum that challenging to accurately diagnose manage. The primary features which PCOS manifests include hyperandrogenism, ovulatory dysfunction, polycystic ovarian morphology, though all three are not necessarily present patients. Hyperandrogenism, manifesting hirsutism, acne, male-pattern alopecia, significantly affects both physical psychological wellbeing these Ovulatory presenting irregular menstrual cycles due oligo/anovulation, an important element PCOS's presentation leads infertility some patients' experience. associated insulin resistance consequent hyperinsulinemia metabolic disorders, seen Subsequently, affected at greater risk obesity, dyslipidemia, diabetes, cardiovascular diseases, particularly later life. rate mood namely depression anxiety, also increased this population. complex nature syndrome makes difficulties patient care, chronic emphasizes proactive stance when it comes treatment, but careful assessment elements disease.

Язык: Английский

Процитировано

PCOS and genetics: Exploring the heterogeneous role of potential genes in ovarian dysfunction, a hallmark of PCOS – A review DOI

Vidhya Dharani,

Susmita Das Nishu,

Hariprasath Lakshmanan

и другие.

Reproductive Biology, Год журнала: 2025, Номер 25(2), С. 101017 - 101017

Опубликована: Апрель 12, 2025

Язык: Английский

Процитировано

The role of macrophages in polycystic ovary syndrome: A review DOI

Li Li, Yubo Xiao, Wen Wang

и другие.

Medicine, Год журнала: 2025, Номер 104(17), С. e42228 - e42228

Опубликована: Апрель 25, 2025

Polycystic ovary syndrome (PCOS) is a common endocrine disorder among fertile women, which influenced by genetics and environment. A recent study revealed that PCOS patients were in chronic inflammatory state, they had abnormally activated macrophages. This paper introduces the relationship between The forkhead box protein O1 (FOXO-1), migration inhibitory factor, sympathetic conservation disorder, vitamin D are believed to influence macrophages PCOS. There evidence PCOS-associated abnormalities associated with macrophages, including insulin resistance, obesity, hyperandrogenism (HA), hyperhomocysteinemia (HHcy), cardiometabolic gut microbiota dysbiosis. review summarizes research status of Macrophages might be potential treatment candidate.

Язык: Английский

Процитировано

Polycystic ovary syndrome: Recent research and therapeutic advancements DOI

Shanmugapriya Dilliyappan,

Avanthika Satish Kumar,

Sneha Venkatesalu

и другие.

Life Sciences, Год журнала: 2024, Номер 359, С. 123221 - 123221

Опубликована: Ноя. 8, 2024

Язык: Английский

Процитировано

Disparities in the Diagnosis and Management of Polycystic Ovarian Syndrome in Adolescents DOI

Stephanie W. Waldrop,

Michaela Buenaventura,

Karen J. Campoverde Reyes

и другие.

Endocrinology and Metabolism Clinics of North America, Год журнала: 2025, Номер unknown

Опубликована: Апрель 1, 2025

Язык: Английский

Процитировано

Platycodin D ameliorates polycystic ovary syndrome-induced ovarian damage by upregulating CD44 to attenuate ferroptosis DOI

Rui Ji,

Shujun Wang,

Xin Chen

и другие.

Free Radical Biology and Medicine, Год журнала: 2024, Номер 224, С. 707 - 722

Опубликована: Сен. 24, 2024

Язык: Английский

Процитировано