Association between combined healthy lifestyles and infertility: a cross-sectional study in US reproductive-aged women
BMC Public Health,
Год журнала:
2025,
Номер
25(1)
Опубликована: Янв. 14, 2025
Язык: Английский
The application of progesterone-primed ovarian stimulation protocol in patients with ovarian endometriosis combined with diminished ovarian reserve
Qingqing Sun,
Yijuan Cao,
Juan Gu
и другие.
BMC Women s Health,
Год журнала:
2025,
Номер
25(1)
Опубликована: Фев. 18, 2025
The
aim
was
to
investigate
the
value
of
application
a
progesterone-primed
ovarian
stimulation
(PPOS)
protocol
in
patients
with
endometriosis
(OEM)
combined
diminished
reserve
(DOR).
A
retrospective
analysis
95
OEM
DOR
who
underwent
vitro
fertilization/intracytoplasmic
sperm
injection-embryo
transfer
(IVF/ICSI-ET)
conducted
between
March
2020
and
February
2024
at
Reproductive
Center
Xuzhou
Central
Hospital.
Patients
were
divided
into
two
groups
on
basis
used:
PPOS
group
(n
=
60,
60
cycles)
GnRH
agonist
downregulation
35,
35
cycles).
General
data,
outcomes,
pregnancy
outcomes
compared
groups.
There
no
statistically
significant
differences
terms
general
data
(P
>
0.05).
Compared
group,
presented
significantly
more
Gn
days
higher
dosages
<
However,
there
number
oocytes
retrieved,
metaphase
II
oocyte
rate,
fertilization
cleavage
high-quality
embryo
or
cycle
cancellation
rate
Additionally,
observed
parameters,
endometrial
thickness,
implantation
clinical
ectopic
early
miscarriage
In
DOR,
had
comparable
those
protocol,
added
advantage
being
cost-effective.
Язык: Английский
Embryological and pregnancy outcomes of IVF-ET in overweight/obese and normal-weight women with PCOS
Frontiers in Endocrinology,
Год журнала:
2025,
Номер
16
Опубликована: Март 27, 2025
Introduction
Female
obesity
has
been
conclusively
associated
with
compromised
fertility,
adverse
pregnancy
outcomes
and
higher
risks
of
obstetric
neonatal
complications.
However,
it
remains
unclear
whether
the
observed
in
IVF
treatments
among
women
are
primarily
due
to
itself
or
underlying
pathologies
such
as
PCOS.
Studies
investigating
impact
overweight/obesity
compared
normal
weight
PCOS
have
yielded
inconsistent
findings.
Methods
We
retrospectively
analyzed
4083
undergoing
first
IVF-ET
cycle
antagonist
protocol.
Among
them,
1755
were
divided
into
group
(18.5
g/m
2
≤
BMI
<
24.0
kg/m
),
1398
overweight
(24.0
28.0
)
930
obese
(BMI
≥
).
The
primary
outcome
was
live
birth.
Other
parameters,
embryological,
birth
newborns.
additionally
investigated
potential
associations
maternal
a
continuous
variable
for
both
linear
non-linear
associations.
Result
Women
had
fewer
numbers
oocytes
retrieved
(adjusted
B:
-0.82
[-1.17
-0.47]
adjusted
-1.86
[-2.26
-1.46],
respectively),
2PN
-0.52
[-0.78
-0.26]
-1.46]),
good-quality
embryos
-0.34
[-0.57
-0.12]
-0.88
[-1.13
-0.62]),
weight.
rate
35.7%,
30.6%
27.2%
group,
respectively
OR:0.76
[0.65
0.89])
verse
weight,
OR:0.64
[0.53
0.76)]
weight).
There
significant
between
outcomes.
did
not
observe
these
Discussion
Overweight
experienced
lower
good
quality
embryos,
reduced
rates
births,
miscarriage
normal-weight
Язык: Английский
Impact of body weight on IVF: pathophysiology, outcomes, and clinical considerations
Current Opinion in Obstetrics & Gynecology,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 25, 2025
This
study
aimed
to
examine
if
excess
body
weight
impacts
the
outcomes
of
IVF
treatment
cycles.
While
data
on
effect
and/or
association
continue
produce
mixed
results,
recent
studies
stratifying
analyses
by
age
are
yielding
clarity
a
detrimental
potential
obesity
outcomes.
Specifically,
in
third
decade
life
susceptible
adverse
implications
weight,
as
reflected
lower
clinical
pregnancy
and
live
birth
rates.
Plausible
pathogenic
mechanisms
underlying
impact
include
inflammation,
DNA
repair,
insulin
resistance,
targets
such
that
spectrum
players
critical
reproductive
success,
including
oocyte,
sperm,
embryo,
uterine
receptivity.
The
more
pronounced
age,
inflammatory
processes
seem
be
particularly
relevant
interplay
excess,
adiposity,
cycle
Язык: Английский