Ellagic acid supplementation on oxidative stress, antioxidative capacity and inflammation biomarkers: A systematic review and dose–response meta-analysis of randomized controlled trials

Journal of Functional Foods, Год журнала: 2024, Номер 122, С. 106492 - 106492

Опубликована: Окт. 4, 2024

Язык: Английский

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Efficacy and safety of dietary polyphenol administration as assessed by hormonal, glycolipid metabolism, inflammation and oxidative stress parameters in patients with PCOS: a meta-analysis and systematic review

Critical Reviews in Food Science and Nutrition, Год журнала: 2024, Номер unknown, С. 1 - 25

Опубликована: Дек. 16, 2024

The current knowledge about the efficacy and safety of dietary polyphenol administration in patients with polycystic ovarian syndrome (PCOS) is divergent.

Язык: Английский

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Effects of the DailyColors™ Polyphenol Supplement on Serum Proteome, Cognitive Function, and Health in Older Adults at Risk of Cognitive and Functional Decline.

medRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown

Опубликована: Дек. 8, 2024

Abstract The Mediterranean diet is associated with reduced mortality and cognitive decline, largely due to its polyphenol content. However, Western populations often do not meet recommended fruit vegetable intakes. Polyphenols exert anti-inflammatory effects may influence extracellular vesicle (EV) dynamics. DailyColors™ a polyphenol-rich blend inspired by the Diet, containing extracts from 16 fruits, vegetables, herbs. This 60-day, double-blind, placebo-controlled, randomised trial involved 150 UK adults aged 50+ BMI ≥ 25, recruited complete physical fitness assessments via PROTECT-UK online platform. Participants received either medium (750mg) or high (2000mg) dose of (∼300mg ∼750mg polyphenols, respectively) placebo. A sub-group (n=15 per group) underwent additional assessments, including blood pressure measurements, characterisation circulating EVs tandem-mass-tagged serum proteomics. Significant benefits were observed, improvements in reaction time for high-dose group accuracy both active supplement groups. also showed significant gains on Timed Stand Test (P<0.001). All groups improved Chair Test. Proteomic analysis significantly protein expression immune pre-β1-HDL pathways, suggesting effects. Pre-β1-HDL proteins are typically elevated obesity; their reduction suggests reversal this obesity-related effect. No changes noted EV concentration size. supplementation, enhance function, fitness, systemic health older, overweight adults, potentially mimicking diet. These findings warrant investigation larger trials.

Язык: Английский

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Potential Benefit of Spices for Glycemic Control

Nutrition Today, Год журнала: 2024, Номер 59(4), С. 182 - 194

Опубликована: Июль 1, 2024

The prevalence of hyperglycemia is increasing worldwide in large part due to the escalating obesity. It can occur along with other disorders and diseases, contributing health costs accumulating disabilities. Besides dietary approaches availability antidiabetic medications, complementary adjunct therapies using biologically active botanical phytochemicals have received growing attention for managing type 2 diabetes mellitus. Spices are one source these bioactive plant constituents, considerable preclinical studies investigated their possible benefits. There also an number human clinical trials assessing ability spices individual constituents improve glucose homeostasis those mellitus dysglycemic conditions. This narrative review provides a summary evaluating effects select on highlights areas future research.

Язык: Английский

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Integrative Therapies in Metabolic Syndrome

Integrative and Complementary Therapies, Год журнала: 2024, Номер 30(5), С. 233 - 243

Опубликована: Окт. 1, 2024

Язык: Английский

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