Nutritional and Nutraceutical Support to the Failing Myocardium: A Possible Way of Potentiating the Current Treatment of Heart Failure DOI Open Access
Roberta Macrì, Rocco Mollace,

Maria Serra

и другие.

International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(22), С. 12232 - 12232

Опубликована: Ноя. 14, 2024

Heart failure (HF) is a complex condition that affects 1–2% of the global population. The presence comorbidities like diabetes, hypertension, hyperlipidemia, or obesity has been shown in various studies to elevate mortality and hospitalization rates HF patients. Insufficient outcomes persist HF, necessitating additional research address unmet needs disease management. Lifestyle modifications, including smoking cessation, decreased alcohol consumption, regular exercise, cardiac rehabilitation, balanced diet, can prevent treat wide range cases. In this review, we aimed examine how lifestyle changes, nutrition, nutraceutical supplements play role preventing heart supporting its treatment. A detailed comprehensive analysis most recent data present literature could help identify potential candidates for future clinical trials There growing body evidence importance closely monitoring nutritional balance, micronutrients nutraceuticals, patients better symptom management outcomes. Despite promising results from initial approaches, lack conclusive meta-analyses questions widespread use supplementation Further are necessary determine effective way treatment myocardial dysfunction

Язык: Английский

Wine Grape Pomace as a Dietary Supplement to Improve Semen Quality in Boars DOI
Armando Quintero‐Moreno,

Cristina Martínez‐López,

Chiara Luongo

и другие.

Reproduction in Domestic Animals, Год журнала: 2025, Номер 60(4)

Опубликована: Апрель 1, 2025

ABSTRACT Boar spermatozoa are highly susceptible to oxidative damage due their high content of unsaturated fatty acids, which prone disruption by reactive oxygen species (ROS). Excessive ROS can induce lipid peroxidation, DNA fragmentation and impaired enzyme activity, ultimately reducing sperm quality reproductive performance. Wine grape pomace (WGP), a by‐product the winemaking process, is rich in polyphenols, including flavonoids (anthocyanins quercetin), stilbenes (resveratrol) tannins, possess strong antioxidant properties. This study aimed evaluate effects dietary supplementation with 4% WGP on boar ejaculate output during storage. Twenty boars were divided into two groups: control group fed standard diet supplemented for 4 months. Semen samples collected analysed number per ml, total capacity (in seminal plasma) parameters (motility, kinematic parameters, mitochondrial acrosome integrity, viability) after 1, 3 5 days refrigerated Results showed that increased ml compared ( p < 0.05), resulting approximately additional doses ejaculate, without negatively affecting other > 0.05) refrigeration storage 0.05). improvement concentration could enhance profitability swine semen production increasing produced annually. Given low cost (10.03 €/boar/year), this strategy offer cost‐effective approach improving performance boars. These findings support further research optimising inclusion levels exploring its broader impacts fertility efficiency.

Язык: Английский

Процитировано

0

Insights into grape-derived health benefits: a comprehensive overview DOI Creative Commons
Marta Angela de Almeida Sousa Cruz, Monique de Barros Elias, Daniela Călina

и другие.

Food Production Processing and Nutrition, Год журнала: 2024, Номер 6(1)

Опубликована: Дек. 3, 2024

Abstract Grapes, renowned for their diverse phytochemical composition, have long been recognized health-promoting properties. This narrative review aims to synthesize the current research on grapes, with a particular emphasis role in disease prevention and health enhancement through bioactive compounds. A comprehensive of peer-reviewed studies, including vitro , vivo clinical investigations, was conducted elucidate relationship between grape consumption outcomes. The highlights positive association intake decreased risk chronic diseases such as cardiovascular disease, type 2 diabetes, certain cancers. Notable components like resveratrol are emphasized neuroprotective antioxidative capabilities. Additionally, explores emerging impact grapes gut microbiota its implications metabolic immune function. updated underscores importance future fully leverage understand therapeutic potential grape-derived compounds, aiming refine dietary guidelines functional food formulations. Further translational studies expected clarify specific interactions impacts health. Graphical

Язык: Английский

Процитировано

1

Nutritional and Nutraceutical Support to the Failing Myocardium: A Possible Way of Potentiating the Current Treatment of Heart Failure DOI Open Access
Roberta Macrì, Rocco Mollace,

Maria Serra

и другие.

International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(22), С. 12232 - 12232

Опубликована: Ноя. 14, 2024

Heart failure (HF) is a complex condition that affects 1–2% of the global population. The presence comorbidities like diabetes, hypertension, hyperlipidemia, or obesity has been shown in various studies to elevate mortality and hospitalization rates HF patients. Insufficient outcomes persist HF, necessitating additional research address unmet needs disease management. Lifestyle modifications, including smoking cessation, decreased alcohol consumption, regular exercise, cardiac rehabilitation, balanced diet, can prevent treat wide range cases. In this review, we aimed examine how lifestyle changes, nutrition, nutraceutical supplements play role preventing heart supporting its treatment. A detailed comprehensive analysis most recent data present literature could help identify potential candidates for future clinical trials There growing body evidence importance closely monitoring nutritional balance, micronutrients nutraceuticals, patients better symptom management outcomes. Despite promising results from initial approaches, lack conclusive meta-analyses questions widespread use supplementation Further are necessary determine effective way treatment myocardial dysfunction

Язык: Английский

Процитировано

0