Association between estimated glucose disposal rate with the all-cause and cause-specific mortality among the population with cardiometabolic syndrome
Diabetology & Metabolic Syndrome,
Год журнала:
2025,
Номер
17(1)
Опубликована: Фев. 26, 2025
Estimated
glucose
disposal
rate
(eGDR)
is
considered
as
a
reliable
alternative
indicator
of
insulin
resistance.
However,
the
relationship
between
eGDR
levels
and
mortality
among
individuals
with
cardiometabolic
syndrome
(CMS),
well
within
different
metabolic
states
in
this
population,
remains
unclear.
We
conducted
cohort
study
on
9928
CMS
participants
from
National
Health
Nutrition
Examination
Survey
(NHANES)
database
1999
to
2018.
The
population
was
evaluated
using
multivariable
Cox
proportional
hazards
regression
models
restricted
cubic
splines
(RCS).
Finally,
stratified
analysis
performed
determine
subgroups.
showed
significant
correlation
both
all-cause
cause-specific
entire
(all
p
<
0.05).
RCS
revealed
non-linear
(p
for
overall
0.001,
0.001)
diabetes
specific
=
0.004)
while
linear
cardiovascular
0.091).
In
baseline
mellitus
(DM),
were
significantly
correlated
mortality,
pre-diabetes
(Pre-DM),
cardiovascular-specific
diabetes-specific
normal
regulation
(NGR),
only
related
There
population.
Furthermore,
protective
effect
high
persists
across
various
states.
Язык: Английский
Magnesium depletion score in relation to frailty prevalence and mortality in US older adults: Evidence from 1999–2018 NHANES
Experimental Gerontology,
Год журнала:
2025,
Номер
205, С. 112757 - 112757
Опубликована: Апрель 17, 2025
This
study
aimed
to
explore
the
associations
between
magnesium
depletion
score
(MDS)
and
frailty
prevalence,
as
well
its
prognostic
significance
for
all-cause
cardiovascular
mortality
among
US
older
adults
with
frailty.
We
analyzed
data
from
participating
in
1999-2018
National
Health
Nutrition
Examination
Survey.
The
primary
exposure
was
MDS,
main
outcomes
were
prevalence
of
defined
by
49-item
accumulation-deficit
model
or
frail
participants.
MDS
using
multivariable-adjusted
logistic
regression
Cox
proportional
hazards
models,
respectively.
Overall,
13,551
participants
(mean
age
71.31
years,
45.46
%
men,
4464
frailty)
included.
Compared
=
0
group,
odds
ratio
95
confidence
interval
(CI)
1.144
(0.899-1.456),
1.702
(1.327-2.183),
2.661
(2.038-3.475)
1,
2,
≥
3
groups,
A
total
2195
(791
cardiovascular-related)
deaths
occurred
during
a
median
follow-up
70
months.
hazard
ratios
CIs
groups
1.509
(1.146-1.986),
1.988
(1.515-2.611),
2.751
(2.125-3.562),
respectively,
mortality,
1.376
(0.843-2.246),
1.933
(1.183-3.160),
2.872
(1.817-4.541),
respectively
mortality.
higher
is
related
increased
risk
adults.
Язык: Английский