Phytopathology, Год журнала: 2025, Номер unknown
Опубликована: Янв. 6, 2025
Sorghum bicolor is the fifth most important cereal crop and expected to gain prominence due its versatility, low input requirements, tolerance hot dry conditions. In warm humid environments, productivity of sorghum severely limited by hemibiotrophic fungal pathogen Colletotrichum sublineola, causal agent anthracnose. Cultivating anthracnose-resistant accessions effective environmentally benign way safeguard yield. A previous genome-wide association study for anthracnose resistance in Association Panel uncovered single-nucleotide polymorphisms on chromosome 5 associated with anthracnose, including one located within coding region gene Sobic. 005G182400. this study, we investigated molecular function 005G182400 response C. sublineola infection. Conserved domain, phylogenetic, structural analyses revealed that protein encoded shares significant similarity Arabidopsis BRASSINOSTEROID INSENSITIVE1-ASSOCIATED RECEPTOR KINASE1 (BAK1)/SOMATIC EMBRYOGENESIS RECEPTOR-LIKE KINASE4 (SERK4). Although sequence analysis four showed no substantial variation region, accession SC1330, which carries allele, exhibited significantly higher expression during early infection (≤24 h). Co-expression network identified module was enriched genes involved endocytosis, autophagy, vesicle transport. Gene regulatory further suggested regulates required BAK1/SERK4-mediated cell death via glycosylation. Together, these findings indicate encodes a BAK1/SERK4 enables pathogen-associated patterns-triggered immunity death.
Язык: Английский