Diet
habit
plays
a
vital
role
in
fecal
incontinence
(FI)
progression.
However,
it
remains
unknown
whether
dietary
quality
is
related
to
FI.
Our
study
sought
explore
the
relationship
between
healthy
eating
index-2015
(HEI-2015)
score
and
FI
among
US
adults.
An
analysis
of
data
from
2005–2010
National
Health
Nutrition
Examination
Survey
was
conducted
our
study.
The
Bowel
Questionnaire
defined
as
losing
liquid,
solid,
or
mucus
stool
at
least
monthly.
diet's
evaluated
using
HEI-2015
score.
odds
ratios
(ORs)
95%
confidence
interval
(95%CI)
were
calculated
multi-variable
logistic
regression
models.
There
11,452
participants,
with
9.3%
(1062/11452)
who
experienced
Compared
individuals
inadequate
group
(HEI
<
50),
adjusted
OR
values
for
HEI
average
(50
≤
70)
optimal
≥
0.89
(95%CI:
0.74–1.07,
p
=
0.214)
0.69
0.52–0.91,
0.011),
respectively.
Subsequent
stratified
analyses
did
not
reveal
any
interactions.
High-quality
diets
are
lower
risk
Therefore,
imperative
take
into
account
potential
impact
diet
on
when
devising
strategies
treatment
prevention.
Lipids in Health and Disease,
Год журнала:
2025,
Номер
24(1)
Опубликована: Май 6, 2025
Polyunsaturated
fatty
acids
(PUFAs)
have
shown
notable
protective
effects
in
various
diseases.
This
study
aims
to
investigate
the
associations
between
PUFAs
intake
and
both
chronic
constipation
(CC)
diarrhea
(CD).
Data
from
three
survey
cycles
(2005-2006,
2007-2008,
2009-2010)
of
National
Health
Nutrition
Examination
Survey
(NHANES)
were
used
for
analysis.
24-hour
dietary
recall
interviews
employed
evaluate
intake.
The
CC
CD
analyzed
via
multivariable
weighted
logistic
regression
(WLR).
Furthermore,
stratified
analysis
restricted
cubic
splines
carried
out.
7723
participants
included,
among
whom
545
(8.35%)
patients
579
(7.50%)
patients.
According
results
MLR,
a
nonlinear
association
was
found
(P
<
0.05),
where
increased
daily
related
declined
prevalence
[OR
=
0.976
(0.959,
0.993),
P
0.007]
fully
adjusted
model.
However,
there
no
significant
evidence
an
>
0.05).
negatively
associated
with
not
strongly
CD.
It
suggested
that
adjusting
may
alleviate
symptoms.
Not
applicable.
Food Science & Nutrition,
Год журнала:
2025,
Номер
13(6)
Опубликована: Май 27, 2025
ABSTRACT
Sleep
disorders
are
a
common
health
problem
affecting
significant
proportion
of
the
adult
population.
Emerging
evidence
suggests
that
dietary
factors,
particularly
polyunsaturated
fatty
acid
(PUFA)
intake,
may
play
role
in
modulating
sleep
quality.
This
study
aims
to
investigate
association
between
omega‐3
(ω‐3)
and
omega‐6
(ω‐6)
PUFA
using
cross‐sectional
survey
data
from
genome‐wide
studies
(GWAS).
Using
National
Health
Nutrition
Examination
Survey
(NHANES,
2005–2018),
we
analyzed
cohort
31,920
participants,
with
primary
independent
variables
being
intake
ω‐3
ω‐6
PUFAs.
Multivariate
regression
was
used
assess
associations,
restricted
cubic
spline
analysis
explore
potential
non‐linear
dose–response
relationships.
Two‐sample
Mendelian
randomization
(MR)
analyses
were
performed
evaluate
causal
effects
levels
multiple
acids
on
risk
disorders.
For
NHANES
data,
participants
had
significantly
lower
(1.71
±
1.11
g)
compared
those
without
(1.78
1.14
g,
p
<
0.001).
Regression
revealed
higher
associated
reduced
disorders,
while
MR
showed
ratio
total
causally
(IVW
OR
=
0.930,
95%
CI:
0.880–0.983,
0.011).
Our
findings
suggest
increased
FA
level
be
highlighting
benefits
modification
for
health.
Future
research
should
further
these
associations
consider
intervention
establish
causality
optimal
recommendations
prevent
Pharmaceuticals,
Год журнала:
2024,
Номер
17(11), С. 1449 - 1449
Опубликована: Окт. 30, 2024
The
Amazon
rainforest
is
an
important
reservoir
of
biodiversity,
offering
vast
potential
for
the
discovery
new
bioactive
compounds
from
plants.
In
vitro
studies
allow
investigation
biological
processes
and
interventions
in
a
controlled
manner,
making
them
fundamental
pharmacological
biotechnological
research.
These
approaches
are
faster
less
costly
than
vivo
studies,
providing
standardized
conditions
that
enhance
reproducibility
precision
data.
However,
methods
have
limitations,
including
inability
to
fully
replicate
complexity
living
organism
absence
complete
physiological
context.
Translating
results
models
not
always
straightforward,
due
differences
pharmacokinetics
interactions.
this
context,
aim
literature
review
assess
advantages
disadvantages
search
drugs
Amazon,
identifying
challenges
limitations
associated
with
these
comparing
testing.
Thus,
bioprospecting
involves
evaluating
plant
extracts
through
bioassays
investigate
pharmacological,
antimicrobial,
anticancer
activities.
Phenolic
terpenes
frequently
identified
as
main
agents,
exhibiting
antioxidant,
anti-inflammatory,
antineoplastic
Chemical
characterization,
molecular
modifications,
development
delivery
systems,
such
nanoparticles,
highlighted
improve
therapeutic
efficacy.
Therefore,
offers
great
drugs;
however,
significant
challenges,
standardization
extraction
need
clinical
trials,
must
be
overcome
become
viable
medications.
Diet
habit
plays
a
vital
role
in
fecal
incontinence
(FI)
progression.
However,
it
remains
unknown
whether
dietary
quality
is
related
to
FI.
Our
study
sought
explore
the
relationship
between
healthy
eating
index-2015
(HEI-2015)
score
and
FI
among
US
adults.
An
analysis
of
data
from
2005–2010
National
Health
Nutrition
Examination
Survey
was
conducted
our
study.
The
Bowel
Questionnaire
defined
as
losing
liquid,
solid,
or
mucus
stool
at
least
monthly.
diet's
evaluated
using
HEI-2015
score.
odds
ratios
(ORs)
95%
confidence
interval
(95%CI)
were
calculated
multi-variable
logistic
regression
models.
There
11,452
participants,
with
9.3%
(1062/11452)
who
experienced
Compared
individuals
inadequate
group
(HEI
<
50),
adjusted
OR
values
for
HEI
average
(50
≤
70)
optimal
≥
0.89
(95%CI:
0.74–1.07,
p
=
0.214)
0.69
0.52–0.91,
0.011),
respectively.
Subsequent
stratified
analyses
did
not
reveal
any
interactions.
High-quality
diets
are
lower
risk
Therefore,
imperative
take
into
account
potential
impact
diet
on
when
devising
strategies
treatment
prevention.
