Poultry Science, Год журнала: 2024, Номер 104(2), С. 104698 - 104698
Опубликована: Дек. 19, 2024
Язык: Английский
Antioxidants, Год журнала: 2024, Номер 13(11), С. 1375 - 1375
Опубликована: Ноя. 10, 2024
The intensive broiler farming model has accelerated the development of poultry industry. However, it also inevitably brought about many stressors that lead to oxidative stress in organism. intestine is leading site nutrient digestion, absorption, and metabolism, as well a secretory immune organ. Oxidative animal production can harm intestine, potentially significant losses for Under conditions stress, free radicals are produced animal's body, attacking intestinal mucosal tissues destroying barrier integrity tract, disease. Recently, herbs have been shown favorable safety profile promising application improving poultry. Therefore, future in-depth studies on specific mechanisms their extracts treating provide theoretical basis clinical new therapeutic options injury during farming. This review focuses causes hazards tract poultry, with potential, reference developing applying antioxidants.
Язык: Английский
Процитировано
4
Poultry Science, Год журнала: 2024, Номер 104(1), С. 104671 - 104671
Опубликована: Дек. 13, 2024
This study investigated the effect of isoquinoline alkaloids as an alternative to bacitracin on growth performance, oxidative stress, inflammatory status, and ceca microbiome broilers raised under high stocking density (HSD). A total 1,500 one-day-old male Ross 308 chicks were randomly assigned five treatment groups, with 10 replicate pens per group 30 birds pen, for 37 days. The treatments included normal (NSD, birds/m²), HSD (15 50 ppm Bacitracin (BCT50), 80 (IQA80), 100 (IQA100). From days 11 24, had lower feed efficiency (P < 0.05) compared those in other treatments. heterophil-to-lymphocyte ratio malondialdehyde levels NSD IQA80 BCT50 0.05). higher IL-6 a villus height height-to-crypt depth groups Serum TNF-α was group. Alpha diversity not affected by treatments; however, beta showed reduced microbial diversity, prevalence Enterococcaceae Peptostreptococcaceae. enhanced abundance Lactobacillaceae, Clostridiaceae, Rikenellaceae. increased decreased Rikenellaceae respectively. IQA100 Lachnospiraceae, Leuconostocaceae, Coriobacteriaceae. altered metabolic pathways related carbohydrate lipid metabolism, amino acid biosynthesis. modulated functions, particularly cell wall synthesis, while upregulated involved energy production, secondary metabolite biosynthesis, antioxidant production. Both effective mitigating negative effects immunity, gut health microbiota broilers. Given concerns about antimicrobial resistance, are potent bacitracin, being recommended.
Язык: Английский
Процитировано
3
Frontiers in Microbiology, Год журнала: 2025, Номер 16
Опубликована: Май 21, 2025
This experiment was performed to investigate the impacts of formic acid polymer (FAP) supplementation diet on growth performance, blood metabolites, as well intestinal barrier function related indicators broilers under lipopolysaccharide (LPS) stimulation. A total 450 1-day-old male Arbor Acres with similar body weights were assigned one three experimental groups: control (CON) group, basal diet; LPS (1 mg/kg weight) challenge; LPS+FAP supplemented FAP (1,000 mg/kg) and challenge. Each group had 6 replicates 25 broilers. injected days 17, 19, 21. Samples collected day 21, 3 h post-challenge. The lasted 21 days. treatment reduced immune function, caused systemic inflammation, damage, microbiota dysbiosis in However, significantly reversed these effects by reducing feed-to-gain ratio serum levels interleukin (IL)-1β tumor necrosis factor-α (P < 0.05), while increasing complement C4, IL-10, immunoglobulin M 0.05). also improved villus height, trefoil factor family, mucin 2 levels, decreased caspase activities harmful bacteria promoting beneficial bacteria. To sum up, supplementing 1,000 effectively enhanced mitigated inflammatory response damage LPS, thereby improving broiler performance.
Язык: Английский
Процитировано
0
Medicinal Plant Biology, Год журнала: 2024, Номер 3(1), С. 0 - 0
Опубликована: Янв. 1, 2024
Язык: Английский
Процитировано
1
Frontiers in Immunology, Год журнала: 2024, Номер 15
Опубликована: Сен. 23, 2024
The focal point of probiotic efficacy and a crucial factor influencing poultry cultivation lies in the level intestinal inflammation. In conventional farming processes, reduction inflammation generally proves advantageous for growth. This study investigated impact Bacillus amyloliquefaciens TL (B.A.-TL) on inflammatory expression at both tissue cellular levels, alongside an exploration main active secondary metabolites. results demonstrated that broiler feeding with basal diet containing 4 × 10 9 CFU/kg B.A.-TL markedly enhanced chicken growth performance, concomitant significant decrease genes encoding cytokines (e.g., CCL4 , CCR5 XCL1 IL-1β IL-6 IL-8 LITAF LYZ ) jejunum ileum tissues. extracellular polysaccharides (EPS-TL) exhibited notable suppression elevated cytokine induced by Escherichia coli O55 lipopolysaccharides (LPS) macrophage-like cells (HD11) primary embryonic small epithelial (PCIECs). Moreover, EPS-TL inhibitory effect NF-κB signaling pathway activation. These findings suggested metabolic product (i.e., EPS-TL) could partly mitigate factors LPS stimulation, indicating its potential as key component contributing to anti-inflammatory effects B.A.-TL.
Язык: Английский
Процитировано
1
Poultry Science, Год журнала: 2024, Номер 104(2), С. 104698 - 104698
Опубликована: Дек. 19, 2024
Язык: Английский
Процитировано
0