International Journal of Molecular Sciences,
Год журнала:
2025,
Номер
26(4), С. 1605 - 1605
Опубликована: Фев. 13, 2025
Alexandrium
pacificum,
a
dinoflagellate
known
for
causing
harmful
algal
blooms
(HABs),
has
garnered
significant
attention
due
to
its
potential
toxicity
marine
ecosystems,
fisheries,
and
human
health.
However,
the
effects
of
this
toxin-producing
alga
on
shrimp
are
not
yet
comprehensively
understood.
This
study
aimed
assess
hepatopancreas
damage
induced
by
A.
pacificum
in
economically
important
species
E.
carinicauda
elucidate
underlying
molecular
mechanisms
through
histology,
antioxidant
enzyme
activity,
transcriptome
analysis.
The
were
assigned
either
control
group
or
an
exposed
group,
with
latter
involving
exposure
at
concentration
1.0
×
104
cells/mL
7
days.
A
histological
analysis
subsequently
revealed
pathological
changes
tissue
including
lumen
expansion
separation
basement
membrane
from
epithelial
cells,
while
activity
assays
demonstrated
that
weakened
defense
system,
as
evidenced
reduced
activities
catalase,
superoxide
dismutase,
glutathione,
along
increased
malondialdehyde
levels.
Transcriptome
further
identified
663
significantly
upregulated
genes
1735
downregulated
ones
these
differentially
expressed
being
primarily
associated
pathways
such
protein
processing
endoplasmic
reticulum,
mitophagy,
glycolysis/gluconeogenesis,
sphingolipid
metabolism,
glycerophospholipid
metabolism.
provides
novel
insights
into
toxicological
aquatic
organisms
enhances
current
understanding
ecotoxicological
risks
posed
HABs.
Poultry Science,
Год журнала:
2024,
Номер
104(1), С. 104605 - 104605
Опубликована: Ноя. 28, 2024
Intensification
of
poultry
industry
has
led
to
a
surge
in
animal
product
output,
but
this
also
revealed
issues
with
environmental
management
houses,
particularly
the
harmful
effects
high
hydrogen
sulfide
(H
