Dormant Tumor Cells: Current Opportunities and Challenges in Clinical Practice DOI Creative Commons

Emma Boydell,

Maxime Borgeaud, Petros Tsantoulis

и другие.

Onco, Год журнала: 2025, Номер 5(1), С. 3 - 3

Опубликована: Янв. 10, 2025

Tumor dormancy plays a pivotal role in cancer relapse. Dormant tumor cells have been identified distant sites, even early-stage tumors, and are associated with worse outcomes. This review explores the current understanding of molecular cellular mechanisms behind dormancy, including immune system microenvironment. Targeting dormant could be therapeutic strategy to offer long-term remission potentially cure cancer. Unfortunately, translation this knowledge clinical practice is lacking. We assess feasibility detecting measuring practice, give an overview potential targets, both terms maintaining state, eradicating population.

Язык: Английский

Dormant Tumor Cells: Current Opportunities and Challenges in Clinical Practice DOI Creative Commons

Emma Boydell,

Maxime Borgeaud, Petros Tsantoulis

и другие.

Onco, Год журнала: 2025, Номер 5(1), С. 3 - 3

Опубликована: Янв. 10, 2025

Tumor dormancy plays a pivotal role in cancer relapse. Dormant tumor cells have been identified distant sites, even early-stage tumors, and are associated with worse outcomes. This review explores the current understanding of molecular cellular mechanisms behind dormancy, including immune system microenvironment. Targeting dormant could be therapeutic strategy to offer long-term remission potentially cure cancer. Unfortunately, translation this knowledge clinical practice is lacking. We assess feasibility detecting measuring practice, give an overview potential targets, both terms maintaining state, eradicating population.

Язык: Английский

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