Conversion treatment for advanced intrahepatic cholangiocarcinoma: Opportunities and challenges DOI
Jun-Jie Liu, Mi Zhou, Tong Yuan

и другие.

World Journal of Gastroenterology, Год журнала: 2025, Номер 31(15)

Опубликована: Апрель 17, 2025

The prevalence of intrahepatic cholangiocarcinoma (ICC) is increasing globally. Despite advancements in comprehending this intricate malignancy and formulating novel therapeutic approaches over the past few decades, prognosis for ICC remains poor. Owing to high degree insidious onset ICC, numerous cases are detected at intermediate or advanced stages disease, hence eliminating chance surgical intervention. Moreover, because highly invasive characteristics recurrence metastasis postresection prevalent, leading a 5-year survival rate only 20%-35% following surgery. In decade, different methods treatment have been investigated, including transarterial chemoembolization, radioembolization, radiotherapy, systemic therapy, combination therapies. For certain patients with conversion may be utilized facilitate resection manage disease progression. This review summarizes definition downstaging presents clinical experience evidence concerning ICC.

Язык: Английский

Conversion treatment for advanced intrahepatic cholangiocarcinoma: Opportunities and challenges DOI
Jun-Jie Liu, Mi Zhou, Tong Yuan

и другие.

World Journal of Gastroenterology, Год журнала: 2025, Номер 31(15)

Опубликована: Апрель 17, 2025

The prevalence of intrahepatic cholangiocarcinoma (ICC) is increasing globally. Despite advancements in comprehending this intricate malignancy and formulating novel therapeutic approaches over the past few decades, prognosis for ICC remains poor. Owing to high degree insidious onset ICC, numerous cases are detected at intermediate or advanced stages disease, hence eliminating chance surgical intervention. Moreover, because highly invasive characteristics recurrence metastasis postresection prevalent, leading a 5-year survival rate only 20%-35% following surgery. In decade, different methods treatment have been investigated, including transarterial chemoembolization, radioembolization, radiotherapy, systemic therapy, combination therapies. For certain patients with conversion may be utilized facilitate resection manage disease progression. This review summarizes definition downstaging presents clinical experience evidence concerning ICC.

Язык: Английский

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