VEGF-C and Lymphatic Vessel Density in Tumor Tissue of Gastric Cancer: Correlations with Pathoclinical Features and Prognosis DOI Open Access
Mariusz Szajewski, Maciej Ciesielski, Rafał Pęksa

и другие.

Cancers, Год журнала: 2025, Номер 17(9), С. 1406 - 1406

Опубликована: Апрель 23, 2025

Objectives: The objective of this study was to assess the relationship VEGF-C and LVD with pathoclinical factors potential prognostic value survival time gastric cancer patients. Materials methods: A total 103 radically operated patients for who did not undergo neoadjuvant therapy were included in study. minimum follow-up period after surgery 61 months. lymphatic vessels immunohistochemically determined using antibodies, including (c-20) sc 1881-Goat Polyclonal IgG (Santa Cruz Biotechnology) Podoplanin D2-40 Mouse Monoclonal Antibody (ROCHE). between expression adenocarcinoma cells density at periphery primary tumor assessed, along relationships selected parameters prognosis. Results: overexpression associated increased (Mann–Whitney U test, p = 0.03) Lauren intestinal type (Pearson’s chi-square < 0.001). Increased more often cancers located beyond cardia 0.04). We demonstrate an association or OS features, such as pT, pN, pTNM staging. However, cancer, correlated shorter (log-rank, 0.01) and, level 0.05 multivariate analysis, it had independent negative value. Conclusions: Peritumoral tumors is LVD. overexpression. intestinal-type worse

Язык: Английский

Roles of tertiary lymphatic structures in gastric cancer DOI Open Access
Xudong Yan,

Ling-Ling Fan,

Weimin Wang

и другие.

Shijie huaren xiaohua zazhi, Год журнала: 2025, Номер 33(3), С. 178 - 182

Опубликована: Март 28, 2025

Язык: Английский

Процитировано

0
VEGF-C and Lymphatic Vessel Density in Tumor Tissue of Gastric Cancer: Correlations with Pathoclinical Features and Prognosis DOI Open Access
Mariusz Szajewski, Maciej Ciesielski, Rafał Pęksa

и другие.

Cancers, Год журнала: 2025, Номер 17(9), С. 1406 - 1406

Опубликована: Апрель 23, 2025

Objectives: The objective of this study was to assess the relationship VEGF-C and LVD with pathoclinical factors potential prognostic value survival time gastric cancer patients. Materials methods: A total 103 radically operated patients for who did not undergo neoadjuvant therapy were included in study. minimum follow-up period after surgery 61 months. lymphatic vessels immunohistochemically determined using antibodies, including (c-20) sc 1881-Goat Polyclonal IgG (Santa Cruz Biotechnology) Podoplanin D2-40 Mouse Monoclonal Antibody (ROCHE). between expression adenocarcinoma cells density at periphery primary tumor assessed, along relationships selected parameters prognosis. Results: overexpression associated increased (Mann–Whitney U test, p = 0.03) Lauren intestinal type (Pearson’s chi-square < 0.001). Increased more often cancers located beyond cardia 0.04). We demonstrate an association or OS features, such as pT, pN, pTNM staging. However, cancer, correlated shorter (log-rank, 0.01) and, level 0.05 multivariate analysis, it had independent negative value. Conclusions: Peritumoral tumors is LVD. overexpression. intestinal-type worse

Язык: Английский

Процитировано

0