Unraveling Dysgeusia in SARS-CoV-2 Infection: Clinical and Laboratory Insights from Hospitalized COVID-19 Patients in Romania DOI Creative Commons

Elena Camelia Kouris,

Sînziana Irina Mirea,

Sigrid Covaci

и другие.

Pathogens, Год журнала: 2025, Номер 14(4), С. 300 - 300

Опубликована: Март 21, 2025

Introduction: Dysgeusia has been regarded as a clinical feature associated with SARS-CoV-2 infection since the onset of pandemic. The initial circulating variants were linked to presence dysgeusia; however, emergence Omicron variant, incidence dysgeusia decreased. aim this study was identify and characteristics patients from pandemic variant. Methods: We conducted retrospective March 2020 December 2021, among adult hospitalized COVID-19 in main infectious diseases hospital Romania. Clinical laboratory data collected interpreted relation or absence dysgeusia. Results: 32.0%, majority cases (44.2%) occurring Beta predominantly observed mild moderate disease. obesity hypertension shown be negatively development (OR = 0.45, OR 0.39, respectively). In dysgeusia, inflammatory changes such lymphopenia significantly less frequently identified 0.22, p < 0.001), increased C-reactive protein 0.12, 0.001) interleukin-1 0.42, 0.002), fibrinogen 0.31, ferritin 0.27, compared without acute respiratory failure higher group (71.2% vs. 28.8%, 0.001). This accompanied by milder management median duration hospitalization that two days shorter. Conclusions: appears correlate both response outcome. context evolving viral variants, which seem lower continuous monitoring who develop disorder remains essential clarify pathophysiologic mechanisms involved assess potential predictor course infection.

Язык: Английский

Unraveling Dysgeusia in SARS-CoV-2 Infection: Clinical and Laboratory Insights from Hospitalized COVID-19 Patients in Romania DOI Creative Commons

Elena Camelia Kouris,

Sînziana Irina Mirea,

Sigrid Covaci

и другие.

Pathogens, Год журнала: 2025, Номер 14(4), С. 300 - 300

Опубликована: Март 21, 2025

Introduction: Dysgeusia has been regarded as a clinical feature associated with SARS-CoV-2 infection since the onset of pandemic. The initial circulating variants were linked to presence dysgeusia; however, emergence Omicron variant, incidence dysgeusia decreased. aim this study was identify and characteristics patients from pandemic variant. Methods: We conducted retrospective March 2020 December 2021, among adult hospitalized COVID-19 in main infectious diseases hospital Romania. Clinical laboratory data collected interpreted relation or absence dysgeusia. Results: 32.0%, majority cases (44.2%) occurring Beta predominantly observed mild moderate disease. obesity hypertension shown be negatively development (OR = 0.45, OR 0.39, respectively). In dysgeusia, inflammatory changes such lymphopenia significantly less frequently identified 0.22, p < 0.001), increased C-reactive protein 0.12, 0.001) interleukin-1 0.42, 0.002), fibrinogen 0.31, ferritin 0.27, compared without acute respiratory failure higher group (71.2% vs. 28.8%, 0.001). This accompanied by milder management median duration hospitalization that two days shorter. Conclusions: appears correlate both response outcome. context evolving viral variants, which seem lower continuous monitoring who develop disorder remains essential clarify pathophysiologic mechanisms involved assess potential predictor course infection.

Язык: Английский

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