Exposure to sublethal concentrations of imidacloprid, pyraclostrobin, and glyphosate harm the behavior and fat body cells of the stingless bee Scaptotrigona postica

The Science of The Total Environment, Год журнала: 2023, Номер 907, С. 168072 - 168072

Опубликована: Окт. 24, 2023

Язык: Английский

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A comparison of carbon dot and CdTe quantum dot toxicity in Drosophila melanogaster

Environmental Science Advances, Год журнала: 2024, Номер 3(6), С. 912 - 924

Опубликована: Янв. 1, 2024

This work directly compares the toxicity of carbon dots with CdTe quantum in Drosophila melanogaster and reveals that are less toxic than dots.

Язык: Английский

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Toxic effects of acaricide fenazaquin on development, hemolymph metabolome, and gut microbiome of honeybee (Apis mellifera) larvae

Chemosphere, Год журнала: 2024, Номер 358, С. 142207 - 142207

Опубликована: Апрель 30, 2024

Язык: Английский

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Drosophila mutants lacking the glial neurotransmitter-modifying enzyme Ebony exhibit low neurotransmitter levels and altered behavior

Scientific Reports, Год журнала: 2023, Номер 13(1)

Опубликована: Июнь 27, 2023

Inhibitors of enzymes that inactivate amine neurotransmitters (dopamine, serotonin), such as catechol-O-methyltransferase (COMT) and monoamine oxidase (MAO), are thought to increase neurotransmitter levels widely used treat Parkinson's disease psychiatric disorders, yet the role these in regulating behavior remains unclear. Here, we investigated genetic loss a similar enzyme model organism Drosophila melanogaster. Because Ebony modifies inactivates neurotransmitters, its is assumed levels, increasing behaviors aggression courtship decreasing sleep. Indeed, ebony mutants have been described since 1960 "aggressive mutants," though this has not quantified. Using automated machine learning-based analyses, quantitatively confirmed exhibited increased aggressive boxing but also decreased Through tissue-specific knockdown, found ebony's was specific glia. Unexpectedly, direct measurement brains revealed their were reduced. Thus, anomalous for profile. We further only when fighting each other, wild-type controls. Moreover, fights between less likely end with clear winner than controls or In vs. control fights, more win. Together, results suggest exhibit prolonged context, an equally dominant opponent.

Язык: Английский

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Fat body lipogenic capacity in honey bee workers is affected by age, social role, and dietary protein

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown

Опубликована: Март 27, 2024

Abstract All organisms need to balance processes that consume energy against those produce energy. With an increase in biological complexity over evolutionary time, regulation of this has become much more complex, resulting specialization metabolic tasks between organelles, cells, organs, and the case eusocial organisms, individuals who comprise ‘superorganism.’ Exemplifying this, nurse honey bees maintain high abdominal lipids, while foragers have very low lipid stores, likely contributing efficient performance their social role, thus colony fitness. The proximate mechanisms responsible for these differences remain poorly understood. Here, we investigated effects age, age class, dietary macronutrients on activity fatty acid synthase (FAS), enzyme de novo synthesis acids. We found FAS declines as past peak nursing age. Feeding both nurses carbohydrates increased compared with starved bee, but, whether fed or starved, had higher than similarly treated foragers, implicating reduced one component foragers’ stores. Finally, used artificial diets different amounts protein fat precociously induce low, forager-like levels nurse-age deprived protein. speculate appetite consumption during nurse-forager transition is suppressed foragers. Summary statement Honey bee workers show capacity they leave nest forage. Young capacity.

Язык: Английский

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Ketogenesis nutritionally supports brain during bacterial infection in Drosophila

Brain Behavior and Immunity, Год журнала: 2025, Номер 125, С. 280 - 291

Опубликована: Янв. 15, 2025

Язык: Английский

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Sublethal indoxacarb exposure alters pheromone production and ovarian development in the yellow peach moth, Conogethes punctiferalis

Pesticide Biochemistry and Physiology, Год журнала: 2025, Номер 210, С. 106368 - 106368

Опубликована: Март 9, 2025

Язык: Английский

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Antioxidant Activities in the Hemolymph and Fat Body of Physiologically and Prematurely Aging Bees (Apis mellifera)

Antioxidants, Год журнала: 2025, Номер 14(4), С. 373 - 373

Опубликована: Март 21, 2025

Aging is a multifactorial process that occurs in all living organisms, including bees. One of the factors accelerating this stress caused bees by Varroa destructor. The research aim was to compare antioxidant system activities different tissues and fat body segments (sternite, tergite 3 5) workers aging naturally (physiologically) prematurely (affected V. destructor). CAT, GPx, GST, SOD were higher tissues/fat age groups compared workers. These increased with age, reaching maximum at 21 (in sternite) or 28 days hemolymph workers, then decreased oldest ones (at 35 age). In along age. highest identified 5, which may suggest its role detoxification processes. Our results are starting point for better understanding mechanisms related oxidative stress, aging, their correlation health lifespan

Язык: Английский

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The thiamethoxam-based insecticide Cruiser 350 Fs induced histopathological and oxidative stress in the stingless bee Partamona helleri (Hymenoptera: Apidae: Meliponini)

Environmental Toxicology and Pharmacology, Год журнала: 2025, Номер 116, С. 104722 - 104722

Опубликована: Май 21, 2025

Язык: Английский

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Integrating lipid metabolism, pheromone production and perception by Fruitless and Hepatocyte Nuclear Factor 4

Science Advances, Год журнала: 2023, Номер 9(26)

Опубликована: Июнь 30, 2023

Sexual attraction and perception are crucial for mating reproductive success. In Drosophila melanogaster , the male-specific isoform of Fruitless (Fru), Fru M is a known master neuro-regulator innate courtship behavior to control sex pheromones in sensory neurons. Here, we show that non–sex-specific (Fru COM ) necessary pheromone biosynthesis hepatocyte-like oenocytes sexual attraction. Loss resulted adults with reduced levels cuticular hydrocarbons (CHCs), including pheromones, altered hydrophobicity. We further identify Hepatocyte nuclear factor 4 ( Hnf4 as key target directing fatty acid conversion hydrocarbons. or depletion disrupts lipid homeostasis, resulting sex-dimorphic CHC profile differs from doublesex- transformer- dependent dimorphism. Thus, couples production separate organs regulate chemosensory communications ensure efficient behavior.

Язык: Английский

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