Marine Bacterial Secondary Metabolites: A Treasure House for Structurally Unique and Effective Antimicrobial Compounds

Marine Drugs, Год журнала: 2021, Номер 19(10), С. 530 - 530

Опубликована: Сен. 23, 2021

The prevalence of antimicrobial resistance reduces the effectiveness drugs in preventing and treating infectious diseases caused by pathogenic organisms, such as bacteria, fungi, viruses. Because burgeoning growth microbes with antimicrobial-resistant traits, there is a dire need to identify develop novel effective agents treat infections from strains. marine environment rich ecological biodiversity can be regarded an untapped resource for prospecting bioactive compounds. Therefore, exploring plays significant role drug development biomedical research. Several earlier scientific investigations have proven that bacterial diversity represents emerging source structurally unique agents. There are several reports on secondary metabolites, many pharmacologically enormous promise developing combat microbial drug-resistant pathogens. In this review, we attempt summarize published articles last twenty-five years (1996–2020) metabolites bacteria evolved environments, sediment, water, fauna, flora.

Язык: Английский

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Advanced Methods for Natural Products Discovery: Bioactivity Screening, Dereplication, Metabolomics Profiling, Genomic Sequencing, Databases and Informatic Tools, and Structure Elucidation

Marine Drugs, Год журнала: 2023, Номер 21(5), С. 308 - 308

Опубликована: Май 19, 2023

Natural Products (NP) are essential for the discovery of novel drugs and products numerous biotechnological applications. The NP process is expensive time-consuming, having as major hurdles dereplication (early identification known compounds) structure elucidation, particularly determination absolute configuration metabolites with stereogenic centers. This review comprehensively focuses on recent technological instrumental advances, highlighting development methods that alleviate these obstacles, paving way accelerating towards Herein, we emphasize most innovative high-throughput tools advancing bioactivity screening, chemical analysis, dereplication, metabolite profiling, metabolomics, genome sequencing and/or genomics approaches, databases, bioinformatics, chemoinformatics, three-dimensional elucidation.

Язык: Английский

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Exploring the Potential of the Blue Economy: A Systematic Review of Strategies for Enhancing International Business in Bangladesh in the context of Indo-Pacific Region

Review of Business and Economics Studies, Год журнала: 2024, Номер 12(2), С. 55 - 73

Опубликована: Июль 28, 2024

This systematic review aims to provide a methodical analysis of the Blue Economy in Indo-Pacific region, particularly from perspective Bangladesh, focusing on its growth trajectory, key stakeholders, policy frameworks, technological advancements, trade and investment trends, as well challenges opportunities for international business expansion. The methods employed comprehensive search electronic databases, inclusion exclusion criteria were applied identify relevant studies analysis. results revealed that 2000 2020, sectors country, such fisheries, aquaculture, maritime transportation, tourism, saw notable development. International development agencies, corporations, academic institutions, governments, civil society organizations are some major players projects. frameworks facilitate include integrated ocean management, blue initiatives, security governance, resilience adaptation climate change. Innovation expansion have been fueled by breakthroughs, autonomous underwater vehicles, renewable energy projects, remote sensing technologies, marine biotechnology. Rising demand sustainable goods services, technical advancement, regional collaboration all contributed an increase industries internationally. study concludes there is significant potential region drive economic growth, promote social progress, ensure environmental sustainability. However, regulatory complexity, access finance, inadequate infrastructure, degradation need be addressed fully realize this potential. Addressing these requires coordinated efforts businesses, academia, organizations, along with focus inclusive practices.

Язык: Английский

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Supercritical fluid extraction (SCFE) as green extraction technology for high-value metabolites of algae, its potential trends in food and human health

Food Research International, Год журнала: 2021, Номер 150, С. 110746 - 110746

Опубликована: Окт. 12, 2021

Язык: Английский

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From the sea to aquafeed: A perspective overview

Reviews in Aquaculture, Год журнала: 2022, Номер 15(3), С. 1028 - 1057

Опубликована: Окт. 3, 2022

Abstract Aquaculture has been one of the fastest‐growing food production systems sectors for over three decades. With its growth, demand alternative, cheaper and high‐quality feed ingredients is also increasing. Innovation investments on providing new functional alternatives have yielded several viable alternative raw materials. Considering all current ingredients, their circular adaption in aquafeed manufacturing industry clearly utmost importance to achieve sustainable aquaculture near future. The use terrestrial plant materials animal by‐products predominantly used puts a heavily reliance agroecosystems, which own sustainability concerns. Therefore, needs progress with that must be more resilient consistent, considering perspective. In this review, we assess trends using various marine organisms, ranging from microorganisms (including fungi, thraustochytrids, microalgae bacteria) macroalgae macroinvertebrates as biological resources. This review focuses trend resources development value chains. this, present perspective promoting novel economy chains promote re‐use valuable ingredients. Thus, highlight some potentially important marine‐derived deserve further investigations improving or addressing aquaculture.

Язык: Английский

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Metabolic engineering for valorization of macroalgae biomass

Metabolic Engineering, Год журнала: 2022, Номер 71, С. 42 - 61

Опубликована: Янв. 22, 2022

Marine macroalgae have huge potential as feedstocks for production of a wide spectrum chemicals used in biofuels, biomaterials, and bioactive compounds. Harnessing these ways could promote wellbeing people while mitigating climate change environmental destruction linked to use fossil fuels. Microorganisms play pivotal roles converting into valuable products, metabolic engineering technologies been developed extend their native capabilities. This review showcases current achievements the metabolisms various microbial chassis convert red, green, brown bioproducts. Unique features macroalgae, such seasonal variation carbohydrate content salinity, provide next challenges advancing macroalgae-based biorefineries. Three emerging strategies are discussed here: (1) designing dynamic control pathways, (2) strains halophilic (salt-tolerant) microbes, (3) developing consortia conversion. illuminates opportunities future research communities by elucidating approaches microbes so they can become cell factories utilization feedstocks.

Язык: Английский

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A propitious role of marine sourced polysaccharides: Drug delivery and biomedical applications

Carbohydrate Polymers, Год журнала: 2022, Номер 308, С. 120448 - 120448

Опубликована: Дек. 13, 2022

Язык: Английский

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Marine Fungi: Opportunities and Challenges

Encyclopedia, Год журнала: 2022, Номер 2(1), С. 559 - 577

Опубликована: Фев. 28, 2022

Marine fungi play a crucial role in energy flow and nutrient recycling, mediating the cycling of dissolved organic matter marine environments. However, despite being prolific group organisms, have been largely neglected for long time. Besides their importance food web, represent an active source natural products. Over last years, researchers focused on studying organisms to discover new metabolites with antibacterial, antiviral, anticancer activities. Moreover, advances high-throughput sequencing technologies mass spectrometry techniques, genomic metabolomic approaches revealed be paramount products discovery. The mycobiome includes many still identified, ones already known are underutilized biotechnological applications. For this reason, it is undeniable that exploring including habitats substrates, even those remote access, fundamental describing true magnitude Earth’s mycobiome.

Язык: Английский

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Transformation of Seafood Side-Streams and Residuals into Valuable Products

Foods, Год журнала: 2023, Номер 12(2), С. 422 - 422

Опубликована: Янв. 16, 2023

Seafood processing creates enormous amounts of side-streams. This review deals with the use seafood side-streams for transformation into valuable products and identifies suitable approaches making it different purposes. Starting at stage catching fish to its selling point, many parts, such as head, skin, tail, fillet cut-offs, viscera, are wasted. These parts rich in proteins, enzymes, healthy fatty acids monounsaturated polyunsaturated ones, gelatin, collagen. The biochemical composition makes worth discussing paths through which can be turned products. Drawbacks, well challenges aquacultures, demonstrate importance using various produce compounds improve economic performance efficiency sustainability aquaculture. In this review, conventional novel utilization approaches, a combination both, have been identified, will lead development sustainable production chains emergence new bio-based future.

Язык: Английский

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A comprehensive review of the therapeutic potential of cyanobacterial marine bioactives: Unveiling the hidden treasures of the sea

Food and Energy Security, Год журнала: 2023, Номер 12(5)

Опубликована: Авг. 14, 2023

Abstract Marine cyanobacterial bioactives, due to their diverse chemistry and promising pharmacological properties, hold significant potential as therapeutic agents. Here, we comprehensively review the scientific state‐of‐the‐art relating marine including bioprospecting, preclinical clinical studies, mechanisms of action, safety toxicity considerations, sustainability, conservation. We discuss challenges in opportunities for developing bioactives therapeutics; underscore treating life‐threatening health ailments, such cancer neurodegenerative, inflammatory viral diseases. further articulate improving human health, identify future research directions underpinning development therapeutics.

Язык: Английский

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