Global Prevalence and Potential Influencing Factors of COVID-19 Vaccination Hesitancy: A Meta-Analysis

Vaccines, Год журнала: 2022, Номер 10(8), С. 1356 - 1356

Опубликована: Авг. 19, 2022

Countries worldwide have deployed mass COVID-19 vaccination drives, but there are people who hesitant to receive the vaccine. Studies assessing factors associated with hesitancy inconclusive. This study aimed assess global prevalence of and determine potential such hesitancy. We performed an organized search for relevant articles in PubMed, Scopus, Web Science. Extraction required information was each study. A single-arm meta-analysis hesitancy; related vaccine were analyzed using a Z-test. total 56 included our analysis. found that 25%. Being woman, being 50-year-old or younger, single, unemployed, living household five more individuals, having educational attainment lower than undergraduate degree, non-healthcare-related job considering vaccines be unsafe higher risk In contrast, children at home, maintaining physical distancing norms, ever tested COVID-19, history influenza past few years vaccination. Our provides valuable on hesitancy, we recommend special interventions sub-populations increased reduce

Язык: Английский

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Global prevalence and correlates of mpox vaccine acceptance and uptake: a systematic review and meta-analysis

Communications Medicine, Год журнала: 2024, Номер 4(1)

Опубликована: Июль 8, 2024

Vaccination has been recommended as one of the most potent ways controlling mpox (formerly, monkeypox) outbreak, particularly among high-risk groups. Here, we evaluated prevalence vaccine acceptance and uptake globally.

Язык: Английский

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COVID-19 Vaccine Booster Dose Acceptance: Systematic Review and Meta-Analysis

Tropical Medicine and Infectious Disease, Год журнала: 2022, Номер 7(10), С. 298 - 298

Опубликована: Окт. 13, 2022

The World Health Organization (WHO) recommended coronavirus disease 2019 (COVID-19) booster dose vaccination after completing the primary series for individuals ≥18 years and most-at-risk populations. This study aimed to estimate pooled proportion of COVID-19 vaccine uptake intention get among general populations healthcare workers (HCWs). We searched PsycINFO, Scopus, EBSCO, MEDLINE Central/PubMed, ProQuest, SciELO, SAGE, Web Science, Google Scholar, ScienceDirect according PRISMA guidelines. From a total 1079 screened records, 50 studies were extracted. Meta-analysis was conducted using 48 high-quality Newcastle-Ottawa Scale quality assessment tool. Using included studies, acceptance 198,831 subjects 81% (95% confidence interval (CI): 75–85%, I2 = 100%). actual in eight involving 12,995 31% CI: 19–46%, 100%), while have 79% 72–85%, vaccines HCWs 66% 58–74%), 99%). Meta-regression revealed that previous infection associated with lower dose. Conversely, significantly higher level uptake. WHO region Americas, which did not include any vaccination, 77% 66–85%, Western Pacific 89% 84–92%, 100), followed by European region: 86% 81–90%, 99%), Eastern Mediterranean 59% 46–71%, Southeast Asian 52% 43–61%, 95). Having chronic trust effectiveness significant predictors acceptance. global rate is high, but rates vary region. To achieve herd immunity disease, high required. Intensive campaigns programs are still needed around world raise public awareness regarding importance accepting proper control pandemic.

Язык: Английский

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The Race for Global Equitable Access to COVID-19 Vaccines

Vaccines, Год журнала: 2022, Номер 10(8), С. 1306 - 1306

Опубликована: Авг. 12, 2022

COVID-19 vaccines are possibly the most effective medical countermeasures to mitigate and ultimately bring a halt pandemic. As we transition endemicity, inequitable access vaccines, particularly in low- middle-income countries (LMICs), still poses risks of unprecedented disruptions emergence viral mutations, which potentially lead notorious vaccine-resistant variants. The missteps learned from previous responses human immunodeficiency virus (HIV) influenza outbreaks founded hypothetical plan ensure that vaccine accessibility LMICs is not impeded. SARS-CoV-2 vaccines’ social promise was lessen underlying racial, ethnic, geographic inequities has both made apparent intensified. Vaccine nationalism evident throughout crisis. Many high-income directly negotiated large advance orders for leaving resource-limited scrambling access. This occurred despite international initiatives structure development equitable distribution channeled through pillar: Vaccines Global Access (COVAX). serious supply shortages national procurement methods some bypassed pillar hindered optimal function COVAX delivering timely adequate doses participating countries. strategized its approach by promoting fundraising, coordinating donations with surplus doses, expediting reviews candidates, facilitating expansion manufacturing capacity. While increasing capacity production, technology transfer led lesser siloes, enhanced standardization, less secrecy over production data. Ultracold storage requirements leading were considerable hurdle global immunization efforts, limited equipment resources support sophisticated cold-chain systems. Manufacturers strived ease restrictions on basis stability data submitted regulatory bodies. single-dose offered promising solutions simplify administrative logistic complexities existed within vaccination programs. such, ultracold conditions eased, concerns booster addressed. To expand coverage, dosing intervals Oxford/AstraZeneca extended according Phase III clinical trials effectiveness. In addition, recent outbreak monkeypox, lessons past experiences curbing infectious diseases, including COVID-19, must be acted upon. review summarizes efforts respect development, allocation, deployment achieve

Язык: Английский

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Acceptance towards COVID-19 vaccination in Latin America and the Caribbean: A systematic review and meta-analysis

Travel Medicine and Infectious Disease, Год журнала: 2022, Номер 49, С. 102369 - 102369

Опубликована: Июнь 6, 2022

Язык: Английский

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Coronavirus Disease 2019 (COVID-19) Pandemic across Africa: Current Status of Vaccinations and Implications for the Future

Vaccines, Год журнала: 2022, Номер 10(9), С. 1553 - 1553

Опубликована: Сен. 17, 2022

The introduction of effective vaccines in December 2020 marked a significant step forward the global response to COVID-19. Given concerns with access, acceptability, and hesitancy across Africa, there is need describe current status vaccine uptake continent. An exploratory study was undertaken investigate these aspects, challenges, lessons learnt Africa provide future direction. Senior personnel 14 African countries completed self-administered questionnaire, descriptive analysis data. Vaccine roll-out commenced March 2021 most countries. COVID-19 vaccination coverage varied from low Cameroon Tanzania up 39.85% full Botswana at end 2021; that is, all doses advocated by initial protocols versus total population, rates increasing 58.4% June 2022. greatest increase people being fully vaccinated observed Uganda (20.4% increase), (18.5% Zambia (17.9% increase). Most were obtained through WHO-COVAX agreements. Initially, prioritised for healthcare workers (HCWs), elderly, adults co-morbidities, other at-risk groups, now commencing among children administering booster doses. Challenges included irregular supply considerable arising misinformation fuelled social media activities. Overall, fair reasonable access countries, enhanced government initiatives. must be addressed context-specific interventions, including proactive programmes HCWs, medical journalists, public.

Язык: Английский

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Determinants of COVID-19 vaccine acceptance in Ethiopia: A systematic review and meta-analysis

PLoS ONE, Год журнала: 2022, Номер 17(6), С. e0269273 - e0269273

Опубликована: Июнь 3, 2022

Background Vaccination is the promising strategy to control coronavirus disease 2019 (COVID-19) pandemic. However, success of this will rely mainly on rate vaccine acceptance among general population. Therefore, systematic review and meta-analysis aimed estimate pooled prevalence COVID-19 its determinants in Ethiopia. Methods We searched PubMed, Scopus, Google Scholar, African Journals Online, Web Sciences database retrieve related articles. Preferred Reporting Items for Systematic Review Meta-Analysis (PRISMA) guidelines were used study. Funnel plot Eggers test done assess publication bias. Cochrane Q-test I 2 statistic chick evidence heterogeneity. Subgroup analysis was computed based study region Data extracted using a Microsoft Excel spreadsheet analyzed STATA version 14 statistical software. Weighted inverse variance random effect model run acceptance. Results A total 12 studies with 5,029 participants included. The Ethiopia 51.64% (95%CI; 43.95%-59.34%). Being male (AOR = 4.46, 1.19–16.77, 88%), having secondary above educational status 3.97, 1.94–8.12, 69%), good knowledge 3.36, 1.71–6.61, 93%), positive attitude 5.40, 2.43–12.00, 87%) Conclusion low. male, status, knowledge, High level population crucial achieve herd immunity community. policymakers, campaign program planners, stakeholders should target improve public awareness vaccination that enhances turn helps

Язык: Английский

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Intention to receive a COVID-19 vaccine booster dose and associated factors in Malaysia

Human Vaccines & Immunotherapeutics, Год журнала: 2022, Номер 18(5)

Опубликована: Июнь 1, 2022

This study aims to provide evidence of hesitancy in receiving the COVID-19 booster vaccine and associated factors vaccinated population that have completed a primary vaccination series. An anonymous web-based survey was disseminated Malaysian adults aged ≥18 years via social media platforms. A total 1010 responses were collected, which 43.0% (95%CI 39.9–46.0) declared definite willingness receive booster, 38.2% 35.2–44.3) reported being somewhat willing only 5.7% 4.5–7.4) definitely unwilling. Demographically younger participants, those higher income, Chinese ethnicity from central region significantly odds compared reference group (somewhat willing/undecided/somewhat unwilling/definitely unwilling). Having no side effects with past (OR = 2.82, 95% CI 1.33–5.99). lower (range 6–22) pandemic fatigue score 2.34, 1.75–3.22) 24–30) preventive practices 2.45, 1.80–3.34) also willingness. Regarding attitudes toward vaccine, having fewer concerns about uncertain long-term safety multiple vaccinations found create greater booster. Findings this provided insights into demographic characteristics important behavioral attitudinal hesitancy.

Язык: Английский

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Global COVID-19 vaccine acceptance level and its determinants: an umbrella review

BMC Public Health, Год журнала: 2024, Номер 24(1)

Опубликована: Янв. 2, 2024

Abstract Background The COVID-19 vaccination is essential for reducing disease burden on a worldwide scale. success of this strategy will largely depend how well vaccines are received. Previous reviews had produced contradictory results, and there been no umbrella review. Therefore, the objective review was to combine data regarding vaccination’s global acceptance rate its contributing factors. Methods Using PRISMA guideline, PubMed, Embase, Scopus, Web Sciences, Cochrane Database Systematic Reviews, Scopus Google Scholar which reported vaccine and/or determinants were searched. quality included studies assessed using Assessment Multiple Reviews (AMSTAR). A weighted inverse variance random-effects model applied find pooled estimates. subgroup analysis, heterogeneity, publication bias sensitivity analysis also assessed. Result Twenty-two SRM with 10,433,306 study participants included. globally found be 60.23 (95% CI: 58.27, 62.18). In low-income countries, level 54.07(50.31, 57.83) while magnitude 64.32 (62.24,66.40) among across globe. Higher education (AOR =1.96; 95% CI:1.20, 2.73), good knowledge (2.20; CI:1.36, 3.03), favourable attitude =4.50; CI:2.89, 6.12), previous history infection =3.41; CI:1.77, 5.06), male sex =1.62; CI:1.47, 1.77), chronic =1.54; CI:1.18, 1.90) predictors acceptance. Conclusion highly varied unacceptably low particularly in countries. education, knowledge, attitude, COVID-19, sex, factors rate. collaborative effort stakeholders such as policymakers, campaign program planners needed improve vaccine.

Язык: Английский

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COVID-19 Vaccine Hesitancy: Umbrella Review of Systematic Reviews and Meta-Analysis

JMIR Public Health and Surveillance, Год журнала: 2024, Номер 10, С. e54769 - e54769

Опубликована: Апрель 30, 2024

The unprecedented emergence of the COVID-19 pandemic necessitated development and global distribution vaccines, making understanding vaccine acceptance hesitancy crucial to overcoming barriers vaccination achieving widespread immunization.

Язык: Английский

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