Background:
Keratoconus
(KCN)
is
a
progressive
corneal
ectasia
that
manifests
at
young
age
and
significantly
impacts
vision
quality
of
life.
Early
diagnosis
allows
for
effective
treatment
with
collagen
crosslinking,
yet
there
lack
screening
methods.
This
research
aims
to
screen
adolescents
adults
this
sight-threatening
disease
using
quick
tomography
mapping.
Methods:
prospective
cross-sectional
study
being
conducted
Johns
Hopkins
Aramco
Healthcare
in
Saudi
Arabia,
focusing
on
subjects
aged
13-23.
We
are
presenting
the
data
from
our
as
internal
pilot
data.
Bilateral
imaging
Pentacam
HR
(Oculus,
Wetzlar,
Germany),
utilizing
Scheimpflug
tomography,
was
performed.
Historical
allergies,
eye
rubbing,
KCN,
family
history,
previous
surgery,
contact
lens
use
were
collected.
The
Belin
Ambrosio
Enhanced
Ectasia
Display
total
D
value
served
an
objective
criterion
suspect
KCN
(SKCN)
diagnosis.
Results:
In
110
participants,
identified
2.75%
participants
SKCN
11.93%.
Systemic
allergies
or
eczema
reported
by
2.80%,
no
cases
groups.
Eye
rubbing
behavior
observed
5.50%,
highest
prevalence
(33.30%)
group.
A
history
found
21.10%,
having
(30.80%).
Conclusion:
restricted
population
reveals
significant
rate
2.75%.
condition,
easily
detected
treatable
highlights
need
larger
studies
determine
disease's
true
prevalence.
Efficient
programs
tailored
regional
essential
early
detection
intervention.
Purpose:
To
evaluate
the
short-
and
mid-term
clinical
outcomes
of
corneal
allogeneic
intrastromal
ring
segments
(CAIRS)
assess
their
efficacy
safety
in
keratoconus
treatment.
Methods:
Case
series
79
eyes
from
71
patients
with
who
underwent
femtosecond-assisted
CAIRS
implantation
at
Adolphe
de
Rothschild
Hospital
Foundation,
Noémie
Institute.
Preoperative
postoperative
examinations
were
conducted
3
6
months.
Anterior
segment
optical
coherence
tomography
aberrometric
pachymetric
analyses
performed
each
visit.
Visual,
refractive,
topographic
parameters
extracted.
Results:
Corrected
distance
visual
acuity
improved
by
1,
2,
lines
or
more
33%,
44%,
52%
cases,
respectively.
Significant
improvements
observed
K1,
K2,
Km,
Kmax,
astigmatism,
sphere,
cylinder,
spherical
equivalent,
total
root
mean
square,
higher-order
aberrations,
vertical
coma,
aberrations
(all
P
<
0.01
0.05).
Eleven
(13.9%)
dissatisfied
outcomes.
In
addition,
9
(13.65%)
experienced
a
loss
corrected
months
postoperatively
(6
lost
1
line,
2
lines),
yet
remained
satisfied
results
because
refraction
uncorrected
vision.
Conclusions:
This
study
is
largest
to
date
evaluating
implantations
highlights
as
promising
treatment
for
keratoconus.
Annales Academiae Medicae Silesiensis,
Год журнала:
2025,
Номер
79, С. 56 - 63
Опубликована: Март 3, 2025
Wprowadzenie
W
ostatnich
latach
stożek
rogówki
stał
się
często
diagnozowanym
schorzeniem
okulistycznym,
charakteryzującym
postępującym
ścieńczeniem
obszaru
centralnego
lub
paracentralnego
rogówki.
Standardową
metodą
terapeutyczną
jest
cross-linking
(CXL),
który
oferuje
różnorodne
techniki
leczenia
dostosowane
do
zaawansowania
choroby.
Celem
niniejszego
przeglądu
zebranie
i
omówienie
najczęściej
stosowanych
metod
CXL
w
sposób,
ułatwi
lekarzom
dobór
najbardziej
odpowiedniego
planu
terapeutycznego,
uwzględniającego
indywidualne
potrzeby
pacjenta.
Metody
Niniejszy
przegląd
opiera
na
42
artykułach
starannie
wybranych
z
ogólnodostępnych
źródeł,
wykorzystaniem
baz
danych
PubMed
Google
Scholar.
Wyszukiwanie
obejmowało
postępowanie
terapeutyczne
zarówno
u
dorosłych,
jak
dzieci.
Przegląd
literatury
obejmuje
publikacje
lat
2003–2024.
Stan
wiedzy
uważany
za
podstawową
strategię
leczeniu
stożka
Liczne
badania
wskazują,
że
metoda
ta
bardzo
skuteczna
pacjentów
cierpiących
to
schorzenie.
Wnioski
ocenia
różne
metody
CXL.
metodzie
przeznabłonkowego
(<i>transepithelial
cross-linking</i>
–
TE-CXL)
zachowuje
warstwę
nabłonka,
co
zmniejsza
ryzyko
powikłań
pooperacyjnych
umożliwia
leczenie
cieńszych
rogówek
oraz
zaawansowanego
Chociaż
wspomniana
bezpieczniejsza,
mniej
bolesna
sprzyja
szybszemu
powrotowi
zdrowia,
jej
skuteczność
może
być
ograniczona
przez
niewystarczającą
penetrację
ryboflawiny.
Z
kolei
usunięciem
nabłonka
(<i>epithelium-off</i>
epi-off),
zwłaszcza
protokół
drezdeński,
pozostaje
złotym
standardem,
choć
niesie
sobą
powikłań,
takich
ból.
Praca
podkreśla
potrzebę
równoważenia
bezpieczeństwa
skuteczności
przy
wyborze
CXL,
jednoczesnym
uznaniu,
wszystkie
są
skuteczne
hamowaniu
postępu
Journal of Optometry,
Год журнала:
2025,
Номер
18(2), С. 100547 - 100547
Опубликована: Апрель 1, 2025
To
assess
the
fitting
process
and
clinical
feasibility
of
a
novel
large
diameter
rigid
gas-permeable
(RGP)
corneal
contact
lens
(CL)
presenting
regular
or
reverse
geometry
for
managing
keratoconus
(KC).
The
was
designed
to
rest
on
peripheral
cornea
vault
over
cone,
aiming
enhance
visual
quality,
comfort,
physiology.
32
KC
patients
across
all
severity
stages,
including
central,
paracentral
cones
enrolled.
Lens
parameters
were
customized
from
measurements
obtained
via
Oculus
Pentacam
HR
tomography,
mainly
based
sagittal
height
accounting
adequate
tear
film
clearance.
Visual
acuity
(VA),
contrast
sensitivity
(CS),
ocular
complications,
user
satisfaction
evaluated
at
baseline,
one
week
three
months
wear.
Twenty-four
(41
eyes)
fitted
completed
3-month
follow-up
(median
age
28.5
years,
9
females).
A
median
2
trial
lenses
per
eye
(interquartile
range
4.5)
needed
during
process.
Significant
improvements
in
VA
(baseline:
0.32
logMAR;
months:
0.01
p
=
0.002)
CS
(p
<
0.001
frequencies)
observed
compared
baseline
values.
Ocular
complications
remained
below
significance,
with
superior
limbic
keratoconjunctivitis
showing
significant
reduction
time
0.001).
Patient
high,
daily
wear
9.5
h.
Most
users
(79.2%)
reported
consistent
comfort
their
CLs.
RGP
CL
demonstrated
comparable
efficacy
existing
designs,
offering
high
levels
improved
vision
minimal
complications.
Investigative Ophthalmology & Visual Science,
Год журнала:
2025,
Номер
66(4), С. 31 - 31
Опубликована: Апрель 14, 2025
The
purposes
of
this
study
were
to
quantify
the
impact
degraded
binocularity
in
keratoconus
and
its
improvement
with
rigid
contact
lenses
on
a
depth-related
visuomotor
task
that
emulates
complex
activities
daily
living;
determine
whether
performance
may
be
predicted
from
psychophysical
estimates
stereo
threshold.
Participants
instructed
pass
metal
loop
around
wire
convoluted
depth.
Error
rate
speed
measured
26
controls,
30
cases
best-corrected
spectacles,
subset
17
lenses,
10
uncorrected
myopes
acuity
thresholds
comparable
keratoconic
cohort.
Stereo
determined
using
random-dot
stimuli.
Binocular
error
rates
lower
than
monocular
for
myopes,
better-performing
half
(p
<
0.001,
each),
but
not
worst-performing
=
0.07).
improved
0.001).
Within
each
cohort,
was
poorly
correlated
threshold
(r2
0.12,
each).
Monocular
speeds
significantly
binocular
controls
0.003)
Degraded
limit
ability
perform
tasks.
A
portion
loss
overcome
by
lenses.
attributes
are,
however,
predictable
thresholds.