Endophytes and their potential in biotic stress management and crop production

Frontiers in Microbiology, Год журнала: 2022, Номер 13

Опубликована: Окт. 17, 2022

Biotic stress is caused by harmful microbes that prevent plants from growing normally and also having numerous negative effects on agriculture crops globally. Many biotic factors such as bacteria, fungi, virus, weeds, insects, nematodes are the major constrains of tends to increase reactive oxygen species affect physiological molecular functioning led decrease in crop productivity. Bacterial fungal endophytes solution overcome tasks faced with conventional farming, these environment friendly microbial commodities colonize plant tissues without causing any damage. Endophytes play an important role host fitness, uptake nutrients, synthesis phytohormone diminish injury triggered pathogens via antibiosis, production lytic enzymes, secondary metabolites, hormone activation. They reported help coping stress, improving soil health, respectively. Therefore, usage biofertilizers biocontrol agent have developed eco-friendly substitute destructive chemicals for development mitigation stress. Thus, this review highlighted potential biofertilizers, agent, maintenance health sustainable agriculture.

Язык: Английский

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Arbuscular mycorrhizal fungi and production of secondary metabolites in medicinal plants

Mycorrhiza, Год журнала: 2022, Номер 32(3-4), С. 221 - 256

Опубликована: Май 13, 2022

Abstract Medicinal plants are an important source of therapeutic compounds used in the treatment many diseases since ancient times. Interestingly, they form associations with numerous microorganisms developing as endophytes or symbionts different parts plants. Within soil, arbuscular mycorrhizal fungi (AMF) most prevalent symbiotic forming more than 70% vascular In last decade, a number studies have reported positive effects AMF on improving production and accumulation active medicinal this work, we reviewed literature secondary metabolites The major findings follows: impact either directly by increasing plant biomass indirectly stimulating metabolite biosynthetic pathways. magnitude differs depending genotype, strain, environmental context (e.g., light, time harvesting). Different methods cultivation for greenhouse, aeroponics, hydroponics, vitro hairy root cultures) which also compatible AMF. conclusion, inoculation is real avenue quantity quality pharmacological, medical, cosmetic interest.

Язык: Английский

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Review of Shikonin and Derivatives: Isolation, Chemistry, Biosynthesis, Pharmacology and Toxicology

Frontiers in Pharmacology, Год журнала: 2022, Номер 13

Опубликована: Июль 1, 2022

Shikonin and its derivatives, isolated from traditional medicinal plant species of the genus Lithospermum, Alkanna, Arnebia, Anchusa, Onosma, Echium belonging to Boraginaceae family, have numerous applications in foods, cosmetics, textiles. Shikonin, a potent bioactive red pigment, has been used systems cure various ailments is well known for diverse pharmacological potential such as anticancer, antithrombotic, neuroprotective, antidiabetic, antiviral, anti-inflammatory, anti-gonadotropic, antioxidants, antimicrobial insecticidal. Herein, updated research on natural sources, pharmacology, toxicity studies, patents filed worldwide related shikonin approaches shikonin’s biogenic chemical synthesis are reviewed. Furthermore, recent studies establish reliable production meet market demand, functional identification, future clinical development derivatives against diseases presented.

Язык: Английский

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Root colonization by beneficial rhizobacteria

FEMS Microbiology Reviews, Год журнала: 2023, Номер 48(1)

Опубликована: Дек. 12, 2023

Rhizosphere microbes play critical roles for plant's growth and health. Among them, the beneficial rhizobacteria have potential to be developed as biofertilizer or bioinoculants sustaining agricultural development. The efficient rhizosphere colonization of these is a prerequisite exerting their plant functions, but colonizing process underlying mechanisms not been thoroughly reviewed, especially nonsymbiotic rhizobacteria. This review systematically analyzed root compared it with that symbiotic pathogenic bacteria. also highlighted approaches improve efficiency proposed study rhizobacterial from holistic perspective microbiome under more natural conditions.

Язык: Английский

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Functional Endophytes Regulating Plant Secondary Metabolism: Current Status, Prospects and Applications

International Journal of Molecular Sciences, Год журнала: 2023, Номер 24(2), С. 1153 - 1153

Опубликована: Янв. 6, 2023

Endophytes, which are widely found in host plants and have no harmful effects, a vital biological resource. Plant endophytes promote plant growth enhance plants’ resistance to diseases, pests, environmental stresses. In addition, they the synthesis of important secondary metabolites improve potential applicability agriculture, medicine, food, horticulture. this review, we summarize recent progress understanding interaction between construction synthetic microbial communities (SynComs) metaomics analysis plants. The application development prospects other industries also discussed provide reference for further study utilization endophytes.

Язык: Английский

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Engineering Considerations to Produce Bioactive Compounds from Plant Cell Suspension Culture in Bioreactors

Plants, Год журнала: 2021, Номер 10(12), С. 2762 - 2762

Опубликована: Дек. 14, 2021

The large-scale production of plant-derived secondary metabolites (PDSM) in bioreactors to meet the increasing demand for bioactive compounds treatment and prevention degenerative diseases is nowadays considered an engineering challenge due large number operational factors that need be during their design scale-up. plant cell suspension culture (CSC) has presented numerous benefits over other technologies, such as conventional whole-plant extraction, not only avoiding overexploitation species, but also achieving better yields having excellent scaling-up attributes. selection bioreactor configuration depends on intrinsic properties considerations related effect operating conditions thermodynamics, kinetics, transport phenomena, which together are essential accomplishing PDSM. To this end, review, firstly, provides a comprehensive appraisement PDSM, essentially those with demonstrated importance utilization pharmaceutical industries. Then, special attention given PDSM obtained out CSC. Finally, aspects CSC stating kinetics phenomena and, hence, viability accordingly. analysis reviewed configurations will pave way future research focused scaling up, produce high value-added

Язык: Английский

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Environmental friendly bio-dyeing of silk using Alkanna tinctoria based Alkannin natural dye

Industrial Crops and Products, Год журнала: 2022, Номер 186, С. 115301 - 115301

Опубликована: Июль 3, 2022

Язык: Английский

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Biosynthetic Mechanisms of Secondary Metabolites Promoted by the Interaction Between Endophytes and Plant Hosts

Frontiers in Microbiology, Год журнала: 2022, Номер 13

Опубликована: Июль 11, 2022

Endophytes is a kind of microorganism resource with great potential medicinal value. The interactions between endophytes and host not only promote the growth development each other but also drive biosynthesis many new active substances. In this review, we summarized recent reports related to hosts, mainly regarding research progress affecting plants, physiological stress synthesis compounds. Then, discussed positive effects multiomics analysis on their as well application prospects metabolites synthesized by symbiotic interactions. This review may provide reference for further utilization study hosts.

Язык: Английский

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Plants and endophytes interaction: a “secret wedlock” for sustainable biosynthesis of pharmaceutically important secondary metabolites

Microbial Cell Factories, Год журнала: 2023, Номер 22(1)

Опубликована: Ноя. 4, 2023

Abstract Many plants possess immense pharmacological properties because of the presence various therapeutic bioactive secondary metabolites that are great importance in many pharmaceutical industries. Therefore, to strike a balance between meeting industry demands and conserving natural habitats, medicinal being cultivated on large scale. However, enhance yield simultaneously manage pest infestations, agrochemicals routinely used have detrimental impact whole ecosystem, ranging from biodiversity loss water pollution, soil degradation, nutrient imbalance enormous health hazards both consumers agricultural workers. To address challenges, biological eco-friendly alternatives looked upon with high hopes where endophytes pitch as key players due their tight association host plants. The intricate interplay endophytic microorganisms has emerged captivating subject scientific investigation, profound implications for sustainable biosynthesis pharmaceutically important metabolites. This review delves into hidden world "secret wedlock" endophytes, elucidating multifaceted interactions underpin synthesis compounds significance plant hosts. Here, we briefly diversity highlight potential role core endomicrobiome. We also propose successful implementation situ microbiome manipulation through high-end techniques can pave way towards more enriched future.

Язык: Английский

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Deciphering the mechanisms, hormonal signaling, and potential applications of endophytic microbes to mediate stress tolerance in medicinal plants

Frontiers in Plant Science, Год журнала: 2023, Номер 14

Опубликована: Ноя. 15, 2023

The global healthcare market in the post-pandemic era emphasizes a constant pursuit of therapeutic, adaptogenic, and immune booster drugs. Medicinal plants are only natural resource to meet this by supplying an array bioactive secondary metabolites economic, greener sustainable manner. Driven thrust demand for immunity imparting nutraceutical life-saving plant-derived drugs, acreage commercial cultivation medicinal has dramatically increased recent years. Limited resources land water, low productivity, poor soil fertility coupled with climate change, biotic (bacteria, fungi, insects, viruses, nematodes) abiotic (temperature, drought, salinity, waterlogging, metal toxicity) stress necessitate plant productivity enhancement through strategies. Plants evolved intricate physiological (membrane integrity, organelle structural changes, osmotic adjustments, cell tissue survival, reclamation, root-shoot ratio, antibiosis, hypersensitivity, etc.), biochemical (phytohormones synthesis, proline, protein levels, antioxidant enzymes accumulation, ion exclusion, generation heat-shock proteins, synthesis allelochemicals. cellular (sensing signals, signaling pathways, modulating expression stress-responsive genes etc.) mechanisms combat stresses. Endophytes, colonizing different tissues, synthesize novel compounds that can harness mitigate environmental cues, thus making agroecosystems self-sufficient toward green approaches. host set endophytes another interact highly complex manner involving adaptive mechanisms, including appropriate responses triggered stimuli received from sensors situated on cytoplasm transmitting signals transcriptional machinery nucleus withstand stressful environment effectively. Signaling pathways serve as crucial nexus sensing establishing plants’ proper molecular responses. However, underlying critical endophytic microbes meager. This review comprehends diversity endophyte-mediated plant-microbe interactions tolerance understanding cascades defined Leveraging knowledge, researchers design specific microbial formulations optimize health, increase nutrient uptake, boost crop yields, support resilient, agricultural system.

Язык: Английский

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