Egyptian Journal of Botany, Год журнала: 2023, Номер 0(0), С. 0 - 0
Опубликована: Авг. 11, 2023
U LVA selenium nanoparticles (USeNPs) were synthesized and characterized, then examined for their wound healing capacity through in vitro assay showing promising (82.27%) with USeNPs concentration (500µg/mL).We also determined the antifungal potential via agar well diffusion technique, minimum inhibitory (MIC), which was evaluated by a micro-dilution assay.The synergistic effect of individually or combination standard antibiotic (ketoconazole;100μg/mL) studied against Cryptococcus neoformans RCMB 0049001 Candida lipolytica 005007(1).Geotrichum candidum 041001 checked assay, followed transmission electron microscopy to assess different changes most sensitive fungal yeast cells.The results indicated that have C. 005007(1) achieving remarkable inhibition zones.In comparison, no detected on G. 041001.The MIC found be 78.1μg 312.5μg 005007(1), respectively.The biosynthetic strong can elevate strengthen action ketoconazole towards pathogens, this obvious In experiment synergism carried out present study based combining ketoconazole;100μg/mL USeNPs, resulted detached neoformas cells severe dramatic change.
Язык: Английский