Deep brain stimulation in PD: risk of complications, morbidity, and hospitalizations: a systematic review

Frontiers in Aging Neuroscience, Год журнала: 2023, Номер 15

Опубликована: Ноя. 17, 2023

Parkinson's disease (PD) is a progressive and debilitating neurological disorder. While dopaminergic medication improves PD symptoms, continued management complicated by symptom progression, increasing fluctuations, medication-related dyskinesia. Deep brain stimulation (DBS) surgery well-accepted widespread treatment often utilized to address these symptoms in advanced PD. However, DBS may also lead complications requiring hospitalization. In addition, patients with have specialized care needs during hospitalization.This systematic review seeks characterize the risk of hospitalization following surgery. Patient factors modifications surgical techniques that affect are discussed.It found that, when candidates carefully screened, relatively low-risk procedure, but rate somewhat increased for patients.More research needed determine relative influence more vs. itself hospitalization, education about important insure effective patient within hospital.

Язык: Английский

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Parkinson’s Disease and Caregiving Roles, Demands, and Support Needs and Experiences: A Scoping Review

Healthcare, Год журнала: 2025, Номер 13(1), С. 79 - 79

Опубликована: Янв. 4, 2025

Background and Objectives: A public health priority is the increasing number of persons with Parkinson’s disease (PwP), need to provide them support. We sought synthesize experiences relatives or friends—family caregivers—who such Eligibility Criteria: This study was a scoping literature review modeled by PRISMA guidelines. The articles for this fit following inclusion criteria: (1) studies including perspective caregivers PwP, (2) conducted in United States, (3) between January 2019 2024. Sources Evidence: Articles were identified searching PubMed, EBSCO, Ovid databases search terms included following: (Parkinson’s disease) AND (caregiver OR caregiving carer). Results: total 31 included. Most are descriptive (n = 26), quantitative 17), qualitative 7), mixed-methods 2). Gender, race, ethnicity not consistently reported. Findings across demonstrated common roles (e.g., assistance personal care), extensive physical mental strains, social isolation, work financial strain. Benefit-finding also evident among goal securing PwP dignity comfort as progressed. perspectives on benefits challenges context caregiver resources. Conclusions: Future improve racial gender-related diversity address strain health.

Язык: Английский

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User-centred design, validation and clinical testing of an anti-choking mug for people with Parkinson’s disease

Scientific Reports, Год журнала: 2024, Номер 14(1)

Опубликована: Июнь 19, 2024

Oropharyngeal dysphagia, or difficulty initiating swallowing, is a frequent problem in people with Parkinson's disease (PD) and can lead to aspiration pneumonia. The efficacy of pharmacological options limited. Postural strategies, such as chin-down manoeuvre when drinking, have had some degree success but may be difficult for who other limitations dementia neck rigidity, reproduce consistently. Using user-centred design approach multidisciplinary team, we developed tested an anti-choking mug PD that helps angle the head optimum position drinking. reflected anthropometric ergonomic aspects user needs features including regulation water flow rate sip volume, inner slope, thickened handle wide base, which promoted posture used. Prototype testing using digital technology compare flexion angles (the primary outcome), plus clinical outcomes assessed standard tools (Swallowing Clinical Assessment Score Disease (SCAS-PD) Movement Disorder Society-Unified Rating Scale (MDS-UPDRS) Parts II III), found significant improvements range parameters related efficient swallowing safe drinking versus sham mug.

Язык: Английский

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Metabolomic and Lipidomic Analysis of Manganese-Associated Parkinsonism: a Case-Control Study in Brescia, Italy

medRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown

Опубликована: Сен. 6, 2024

Excessive Manganese (Mn) exposure is neurotoxic and can cause Mn-Induced Parkinsonism (MnIP), marked by cognitive motor dysfunction. Although metabolomic lipidomic research in (PD) patients exists, it remains limited. This study hypothesizes distinct profiles based on status, disease diagnosis, their interaction.

Язык: Английский

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