Brain functional training: a perspective article DOI Creative Commons
Marzo Edir Da Silva‐Grigoletto, Marcos Raphael Pereira Monteiro, José Carlos Aragão-Santos

и другие.

Frontiers in Aging, Год журнала: 2024, Номер 5

Опубликована: Июнь 21, 2024

Physical exercise (PE) positively affects the nervous system, impacting morphology and physiology. It increases brain gray white matter, improves cerebral blood flow, stimulates neurogenesis, synaptogenesis, angiogenesis, promoting function. Although already cognition, some training modalities place greater demands on cognitive aspects of physical exercise, such as perceptual-motor visual-motor training. This type approach aims to emphasize adaptations that occur chronically. Specifically for older people, functional training, a multi-component approach, is promising modality functionality using multi-joint, multi-planar exercises mirroring daily activities. However, applying focus in line with proposal maximal benefits remains underexplored.

Язык: Английский

Aerobic Exercise in Rehabilitation of Patients with Parkinson’s Disease DOI Creative Commons
O. V. Guseva

Annals of Clinical and Experimental Neurology, Год журнала: 2025, Номер 18(4), С. 76 - 82

Опубликована: Янв. 4, 2025

Disability due to Parkinson’s disease (PD) is increasing faster than for any other neurodegenerative disorder. A multidisciplinary approach rehabilitation of patients with PD recommended including various types physical training. Because its general beneficial effect, aerobic endurance training necessary all people maintain their health. Aerobic exercise in also used motor and non-motor symptoms. This article justifies the choice intensity, shows challenges selecting intensity based on maximum oxygen consumption influence clinical behavioral factors, difficulties assessing effectiveness therapy wide range amount studies. The summarizes exercises (walking, Nordic walking, a bicycle ergometer treadmill, aquatic exercises) benefits different courses disease. For freezing gait, piece equipment stationary training, walking preferred type outdoor author role treatment symptoms such as depression, cognitive changes, sleep disorders. question about use Hoehn–Yahr grade 4–5 remains open. Further studies are needed evaluate protocols, assess advanced PD.

Язык: Английский

Процитировано

0

Brief Behavioral Activation Therapy is effective on apathy symptoms of the older adults with mild Alzheimer’s disease but not with moderate Alzheimer’s disease DOI
Alireza Karimpour Vazifehkhorani, Issa Hekmati, Akram Rezvanizadeh

и другие.

Aging & Mental Health, Год журнала: 2025, Номер unknown, С. 1 - 10

Опубликована: Фев. 14, 2025

This study aimed to investigate the effectiveness of Brief Behavioral Activation Therapy (BBAT) on apathy symptoms in older adults with Alzheimer's disease (AD) a medical center facility. In an experimental design, 90 AD were replaced into three groups including two (mild group (n = 30), moderate 30)) and control (15 participants mild 15 AD). All completed Dimensional Apathy Scale (DAS) before after eight-session BBAT intervention, follow-up conducted months post-treatment. A 3 x mixed ANOVA was performed analyze differences levels across over time, using SPSS version 26. The revealed significant all dimensions (executive, emotional initial symptoms) among groups. Specifically, between-subject within-subject differences, respectively for main effect time effect, along interaction between time. These findings indicated that patients significantly decreased from pretest post- but there wasn't change group. suggested is effective reducing AD. Early evaluation, diagnosis treatment stages are crucial improving patient outcomes.

Язык: Английский

Процитировано

0

Optimal dose and type of exercise improve the overall balance in adults with Parkinson’s disease: a systematic review and Bayesian network meta-analysis DOI Creative Commons
Xinxiang Fan, Yuan Yuan, Ying Bai

и другие.

Neurological Sciences, Год журнала: 2025, Номер unknown

Опубликована: Май 27, 2025

Язык: Английский

Процитировано

0

Effectiveness of Telemedicine Interventions on Motor and Nonmotor Outcomes in Parkinson Disease: Systematic Review and Network Meta-Analysis (Preprint) DOI
Jiejie Dou, J. Y. Wang, Xianqi Gao

и другие.

Опубликована: Янв. 11, 2025

BACKGROUND Parkinson disease (PD) presents motor and nonmotor challenges that significantly affect quality of life. Telemedicine has emerged as a promising approach to deliver interventions, including exercise performed through remote equipment (e-Exercise), cognitive behavioral training sessions conducted remotely (e-Cognitive), consultations devices (e-Visits), yet their comparative effectiveness remains unclear. OBJECTIVE This paper aimed evaluate the telemedicine interventions on outcomes in PD compare efficacy e-Exercise, e-Cognitive, e-Visits. METHODS A systematic review network meta-analysis were by searching PubMed, MEDLINE, Embase, Cochrane CENTRAL, Web Science November 2024. Randomized controlled trials comparing with usual care included. Outcomes assessed included total symptoms, life, function, depressive anxiety fear falling, 6-minute walk test, walking velocity, balance ability, timed up go. Two investigators independently study selection, data extraction, risk-of-bias assessment using risk bias 2 tool. Data synthesis (1) pairwise meta-analyses random-effects models calculate standardized mean differences (SMDs) differences; (2) Bayesian integrating direct indirect comparisons rank intervention efficacy, transitivity inconsistency evaluated. Evidence was graded GRADE (Grading Recommendations, Assessment, Development Evaluation), incorporating bias, heterogeneity (<i>I</i>²&gt;50% indicating substantial heterogeneity), precision, publication (Egger test). Statistical quantified τ² <i>I</i>². RESULTS 23 studies involving 1330 participants Pairwise demonstrated improved symptoms (SMD=–0.61, 95% CI –1.19 –0.4), function (SMD=0.58, 0.15-1.01), (SMD=–0.46, –0.88 –0.04), (SMD=–0.57, –1.10 –0.03), falling (SMD=–0.48, –0.77 –0.19), test performance (mean difference=18.98, 16.06-21.90 meters). The revealed e-Exercise most effective for improving (SMD=–1.01, credible interval [CrI] –1.96 –0.05) performance. e-Cognitive enhancing life (SMD=0.39, CrI 0.06-0.73) (SMD=1.02, 0.38-1.66), reducing (SMD=–1.28, –1.61 –0.96) (SMD=–1.07, –1.40 –0.75). e-Visits had limited impact across outcomes. moderate or high depression, but low very other CONCLUSIONS is PD. optimal physical performance, while psychological challenges. These findings highlight importance tailoring programs address specific therapeutic needs management. CLINICALTRIAL PROSPERO CRD42024628687; https://www.crd.york.ac.uk/PROSPERO/view/CRD42024628687

Язык: Английский

Процитировано

0

Effectiveness of Telemedicine Interventions on Motor and Nonmotor Outcomes in Parkinson Disease: Systematic Review and Network Meta-Analysis DOI Creative Commons
Jiejie Dou, J. Y. Wang, Xianqi Gao

и другие.

Journal of Medical Internet Research, Год журнала: 2025, Номер 27, С. e71169 - e71169

Опубликована: Июнь 3, 2025

Parkinson disease (PD) presents motor and nonmotor challenges that significantly affect quality of life. Telemedicine has emerged as a promising approach to deliver interventions, including exercise performed through remote equipment (e-Exercise), cognitive behavioral training sessions conducted remotely (e-Cognitive), consultations devices (e-Visits), yet their comparative effectiveness remains unclear. This paper aimed evaluate the telemedicine interventions on outcomes in PD compare efficacy e-Exercise, e-Cognitive, e-Visits. A systematic review network meta-analysis were by searching PubMed, MEDLINE, Embase, Cochrane CENTRAL, Web Science November 2024. Randomized controlled trials comparing with usual care included. Outcomes assessed included total symptoms, life, function, depressive anxiety fear falling, 6-minute walk test, walking velocity, balance ability, timed up go. Two investigators independently study selection, data extraction, risk-of-bias assessment using risk bias 2 tool. Data synthesis (1) pairwise meta-analyses random-effects models calculate standardized mean differences (SMDs) differences; (2) Bayesian integrating direct indirect comparisons rank intervention efficacy, transitivity inconsistency evaluated. Evidence was graded GRADE (Grading Recommendations, Assessment, Development Evaluation), incorporating bias, heterogeneity (I²>50% indicating substantial heterogeneity), precision, publication (Egger test). Statistical quantified τ² I². 23 studies involving 1330 participants Pairwise demonstrated improved symptoms (SMD=-0.61, 95% CI -1.19 -0.4), function (SMD=0.58, 0.15-1.01), (SMD=-0.46, -0.88 -0.04), (SMD=-0.57, -1.10 -0.03), falling (SMD=-0.48, -0.77 -0.19), test performance (mean difference=18.98, 16.06-21.90 meters). The revealed e-Exercise most effective for improving (SMD=-1.01, credible interval [CrI] -1.96 -0.05) performance. e-Cognitive enhancing life (SMD=0.39, CrI 0.06-0.73) (SMD=1.02, 0.38-1.66), reducing (SMD=-1.28, -1.61 -0.96) (SMD=-1.07, -1.40 -0.75). e-Visits had limited impact across outcomes. moderate or high depression, but low very other is PD. optimal physical performance, while psychological challenges. These findings highlight importance tailoring programs address specific therapeutic needs management. PROSPERO CRD42024628687; https://www.crd.york.ac.uk/PROSPERO/view/CRD42024628687.

Язык: Английский

Процитировано

0

Brain functional training: a perspective article DOI Creative Commons
Marzo Edir Da Silva‐Grigoletto, Marcos Raphael Pereira Monteiro, José Carlos Aragão-Santos

и другие.

Frontiers in Aging, Год журнала: 2024, Номер 5

Опубликована: Июнь 21, 2024

Physical exercise (PE) positively affects the nervous system, impacting morphology and physiology. It increases brain gray white matter, improves cerebral blood flow, stimulates neurogenesis, synaptogenesis, angiogenesis, promoting function. Although already cognition, some training modalities place greater demands on cognitive aspects of physical exercise, such as perceptual-motor visual-motor training. This type approach aims to emphasize adaptations that occur chronically. Specifically for older people, functional training, a multi-component approach, is promising modality functionality using multi-joint, multi-planar exercises mirroring daily activities. However, applying focus in line with proposal maximal benefits remains underexplored.

Язык: Английский

Процитировано

2