Aerobic Exercise in Rehabilitation of Patients with Parkinson’s Disease
Annals of Clinical and Experimental Neurology,
Год журнала:
2025,
Номер
18(4), С. 76 - 82
Опубликована: Янв. 4, 2025
Disability
due
to
Parkinson’s
disease
(PD)
is
increasing
faster
than
for
any
other
neurodegenerative
disorder.
A
multidisciplinary
approach
rehabilitation
of
patients
with
PD
recommended
including
various
types
physical
training.
Because
its
general
beneficial
effect,
aerobic
endurance
training
necessary
all
people
maintain
their
health.
Aerobic
exercise
in
also
used
motor
and
non-motor
symptoms.
This
article
justifies
the
choice
intensity,
shows
challenges
selecting
intensity
based
on
maximum
oxygen
consumption
influence
clinical
behavioral
factors,
difficulties
assessing
effectiveness
therapy
wide
range
amount
studies.
The
summarizes
exercises
(walking,
Nordic
walking,
a
bicycle
ergometer
treadmill,
aquatic
exercises)
benefits
different
courses
disease.
For
freezing
gait,
piece
equipment
stationary
training,
walking
preferred
type
outdoor
author
role
treatment
symptoms
such
as
depression,
cognitive
changes,
sleep
disorders.
question
about
use
Hoehn–Yahr
grade
4–5
remains
open.
Further
studies
are
needed
evaluate
protocols,
assess
advanced
PD.
Язык: Английский
Brief Behavioral Activation Therapy is effective on apathy symptoms of the older adults with mild Alzheimer’s disease but not with moderate Alzheimer’s disease
Aging & Mental Health,
Год журнала:
2025,
Номер
unknown, С. 1 - 10
Опубликована: Фев. 14, 2025
This
study
aimed
to
investigate
the
effectiveness
of
Brief
Behavioral
Activation
Therapy
(BBAT)
on
apathy
symptoms
in
older
adults
with
Alzheimer's
disease
(AD)
a
medical
center
facility.
In
an
experimental
design,
90
AD
were
replaced
into
three
groups
including
two
(mild
group
(n
=
30),
moderate
30))
and
control
(15
participants
mild
15
AD).
All
completed
Dimensional
Apathy
Scale
(DAS)
before
after
eight-session
BBAT
intervention,
follow-up
conducted
months
post-treatment.
A
3
x
mixed
ANOVA
was
performed
analyze
differences
levels
across
over
time,
using
SPSS
version
26.
The
revealed
significant
all
dimensions
(executive,
emotional
initial
symptoms)
among
groups.
Specifically,
between-subject
within-subject
differences,
respectively
for
main
effect
time
effect,
along
interaction
between
time.
These
findings
indicated
that
patients
significantly
decreased
from
pretest
post-
but
there
wasn't
change
group.
suggested
is
effective
reducing
AD.
Early
evaluation,
diagnosis
treatment
stages
are
crucial
improving
patient
outcomes.
Язык: Английский
Optimal dose and type of exercise improve the overall balance in adults with Parkinson’s disease: a systematic review and Bayesian network meta-analysis
Neurological Sciences,
Год журнала:
2025,
Номер
unknown
Опубликована: Май 27, 2025
Язык: Английский
Effectiveness of Telemedicine Interventions on Motor and Nonmotor Outcomes in Parkinson Disease: Systematic Review and Network Meta-Analysis (Preprint)
Опубликована: Янв. 11, 2025
BACKGROUND
Parkinson
disease
(PD)
presents
motor
and
nonmotor
challenges
that
significantly
affect
quality
of
life.
Telemedicine
has
emerged
as
a
promising
approach
to
deliver
interventions,
including
exercise
performed
through
remote
equipment
(e-Exercise),
cognitive
behavioral
training
sessions
conducted
remotely
(e-Cognitive),
consultations
devices
(e-Visits),
yet
their
comparative
effectiveness
remains
unclear.
OBJECTIVE
This
paper
aimed
evaluate
the
telemedicine
interventions
on
outcomes
in
PD
compare
efficacy
e-Exercise,
e-Cognitive,
e-Visits.
METHODS
A
systematic
review
network
meta-analysis
were
by
searching
PubMed,
MEDLINE,
Embase,
Cochrane
CENTRAL,
Web
Science
November
2024.
Randomized
controlled
trials
comparing
with
usual
care
included.
Outcomes
assessed
included
total
symptoms,
life,
function,
depressive
anxiety
fear
falling,
6-minute
walk
test,
walking
velocity,
balance
ability,
timed
up
go.
Two
investigators
independently
study
selection,
data
extraction,
risk-of-bias
assessment
using
risk
bias
2
tool.
Data
synthesis
(1)
pairwise
meta-analyses
random-effects
models
calculate
standardized
mean
differences
(SMDs)
differences;
(2)
Bayesian
integrating
direct
indirect
comparisons
rank
intervention
efficacy,
transitivity
inconsistency
evaluated.
Evidence
was
graded
GRADE
(Grading
Recommendations,
Assessment,
Development
Evaluation),
incorporating
bias,
heterogeneity
(<i>I</i>²>50%
indicating
substantial
heterogeneity),
precision,
publication
(Egger
test).
Statistical
quantified
τ²
<i>I</i>².
RESULTS
23
studies
involving
1330
participants
Pairwise
demonstrated
improved
symptoms
(SMD=–0.61,
95%
CI
–1.19
–0.4),
function
(SMD=0.58,
0.15-1.01),
(SMD=–0.46,
–0.88
–0.04),
(SMD=–0.57,
–1.10
–0.03),
falling
(SMD=–0.48,
–0.77
–0.19),
test
performance
(mean
difference=18.98,
16.06-21.90
meters).
The
revealed
e-Exercise
most
effective
for
improving
(SMD=–1.01,
credible
interval
[CrI]
–1.96
–0.05)
performance.
e-Cognitive
enhancing
life
(SMD=0.39,
CrI
0.06-0.73)
(SMD=1.02,
0.38-1.66),
reducing
(SMD=–1.28,
–1.61
–0.96)
(SMD=–1.07,
–1.40
–0.75).
e-Visits
had
limited
impact
across
outcomes.
moderate
or
high
depression,
but
low
very
other
CONCLUSIONS
is
PD.
optimal
physical
performance,
while
psychological
challenges.
These
findings
highlight
importance
tailoring
programs
address
specific
therapeutic
needs
management.
CLINICALTRIAL
PROSPERO
CRD42024628687;
https://www.crd.york.ac.uk/PROSPERO/view/CRD42024628687
Язык: Английский
Effectiveness of Telemedicine Interventions on Motor and Nonmotor Outcomes in Parkinson Disease: Systematic Review and Network Meta-Analysis
Journal of Medical Internet Research,
Год журнала:
2025,
Номер
27, С. e71169 - e71169
Опубликована: Июнь 3, 2025
Parkinson
disease
(PD)
presents
motor
and
nonmotor
challenges
that
significantly
affect
quality
of
life.
Telemedicine
has
emerged
as
a
promising
approach
to
deliver
interventions,
including
exercise
performed
through
remote
equipment
(e-Exercise),
cognitive
behavioral
training
sessions
conducted
remotely
(e-Cognitive),
consultations
devices
(e-Visits),
yet
their
comparative
effectiveness
remains
unclear.
This
paper
aimed
evaluate
the
telemedicine
interventions
on
outcomes
in
PD
compare
efficacy
e-Exercise,
e-Cognitive,
e-Visits.
A
systematic
review
network
meta-analysis
were
by
searching
PubMed,
MEDLINE,
Embase,
Cochrane
CENTRAL,
Web
Science
November
2024.
Randomized
controlled
trials
comparing
with
usual
care
included.
Outcomes
assessed
included
total
symptoms,
life,
function,
depressive
anxiety
fear
falling,
6-minute
walk
test,
walking
velocity,
balance
ability,
timed
up
go.
Two
investigators
independently
study
selection,
data
extraction,
risk-of-bias
assessment
using
risk
bias
2
tool.
Data
synthesis
(1)
pairwise
meta-analyses
random-effects
models
calculate
standardized
mean
differences
(SMDs)
differences;
(2)
Bayesian
integrating
direct
indirect
comparisons
rank
intervention
efficacy,
transitivity
inconsistency
evaluated.
Evidence
was
graded
GRADE
(Grading
Recommendations,
Assessment,
Development
Evaluation),
incorporating
bias,
heterogeneity
(I²>50%
indicating
substantial
heterogeneity),
precision,
publication
(Egger
test).
Statistical
quantified
τ²
I².
23
studies
involving
1330
participants
Pairwise
demonstrated
improved
symptoms
(SMD=-0.61,
95%
CI
-1.19
-0.4),
function
(SMD=0.58,
0.15-1.01),
(SMD=-0.46,
-0.88
-0.04),
(SMD=-0.57,
-1.10
-0.03),
falling
(SMD=-0.48,
-0.77
-0.19),
test
performance
(mean
difference=18.98,
16.06-21.90
meters).
The
revealed
e-Exercise
most
effective
for
improving
(SMD=-1.01,
credible
interval
[CrI]
-1.96
-0.05)
performance.
e-Cognitive
enhancing
life
(SMD=0.39,
CrI
0.06-0.73)
(SMD=1.02,
0.38-1.66),
reducing
(SMD=-1.28,
-1.61
-0.96)
(SMD=-1.07,
-1.40
-0.75).
e-Visits
had
limited
impact
across
outcomes.
moderate
or
high
depression,
but
low
very
other
is
PD.
optimal
physical
performance,
while
psychological
challenges.
These
findings
highlight
importance
tailoring
programs
address
specific
therapeutic
needs
management.
PROSPERO
CRD42024628687;
https://www.crd.york.ac.uk/PROSPERO/view/CRD42024628687.
Язык: Английский
Brain functional training: a perspective article
Frontiers in Aging,
Год журнала:
2024,
Номер
5
Опубликована: Июнь 21, 2024
Physical
exercise
(PE)
positively
affects
the
nervous
system,
impacting
morphology
and
physiology.
It
increases
brain
gray
white
matter,
improves
cerebral
blood
flow,
stimulates
neurogenesis,
synaptogenesis,
angiogenesis,
promoting
function.
Although
already
cognition,
some
training
modalities
place
greater
demands
on
cognitive
aspects
of
physical
exercise,
such
as
perceptual-motor
visual-motor
training.
This
type
approach
aims
to
emphasize
adaptations
that
occur
chronically.
Specifically
for
older
people,
functional
training,
a
multi-component
approach,
is
promising
modality
functionality
using
multi-joint,
multi-planar
exercises
mirroring
daily
activities.
However,
applying
focus
in
line
with
proposal
maximal
benefits
remains
underexplored.
Язык: Английский