Comment on Pain Management Strategies After Hepatectomy, a Narrative Review of Therapeutic Options [Response to Letter]

Journal of Pain Research, Год журнала: 2025, Номер Volume 18, С. 961 - 962

Опубликована: Фев. 1, 2025

Язык: Английский

Postoperative Electroacupuncture Boosts Cognitive Function Recovery after Laparotomy in Mice

Biomolecules, Год журнала: 2024, Номер 14(10), С. 1274 - 1274

Опубликована: Окт. 10, 2024

Postoperative cognitive dysfunction (POCD) is a common complication that affects memory, executive function, and processing speed postoperatively. The pathogenesis of POCD linked to excessive neuroinflammation pre-existing Alzheimer's disease (AD) pathology. Previous studies have shown acupuncture improves cognition in the early phase POCD. However, can last for longer periods (up weeks years). long-term effects are unknown. In this study, we hypothesized electroacupuncture (EA) could reduce inflammation induced by laparotomy over period. We characterized postoperative EA on changes investigated underlying molecular mechanisms mice. Laparotomy was performed 3-month-old mice followed daily treatment 2 weeks. Our data indicated prolonged impairment memory functions, which were mitigated EA. also reduced tau phosphorylation suppressed activation tau-related kinases glia, with comparable ibuprofen. These findings demonstrate beneficial mouse model POCD, suggesting EA's ability suppress may contribute its protective effects. conclusion, be viable non-pharmacological intervention managing different phases medical condition.

Язык: Английский

A qualitative study on the perioperative experiences and demands of haemophilic arthropathy patients undergoing total joint replacement

Haemophilia, Год журнала: 2024, Номер 30(4), С. 1050 - 1058

Опубликована: Июнь 24, 2024

Total joint replacement is the optimal treatment option for patients with severe haemophilic arthritis. Current research emphasizes patient-reported outcomes as a vital measure evaluating surgical and patient satisfaction. Nevertheless, very limited information about subjective experience of perioperative haemophiliacs in literature, highlighting need exploration this area.

Язык: Английский