Visual Light Flicker Stimulation: Promoting Central Fatigue Recovery in Sleep-Deprived Rats DOI
Kun Wang, Kang Chen, Zilin Wei

и другие.

Опубликована: Янв. 1, 2023

Fatigue and sleepiness are among the primary causes of human errors workplace accidents. The application potential light flicker, as a strong environmental stimulus, in combatting fatigue is considerable. present study aimed to investigate anti-central effect flicker (specifically, 40 Hz 20-30 flickers) on sleep-deprived rats. Both C-FOS-positive cell distribution vivo electrophysiology were utilized assess effects stimulation neural networks. Y maze test was employed spontaneous activity exploratory ability rats influenced by visual stimulation. Additionally, changes cortisol serotonin levels blood examined animals' physiological state. results indicate that flickering has significant various brain regions, such thalamus hippocampus, associated with alertness. Moreover, at induced an enrichment beta gamma while suppressing low-frequency theta activity, indicating enhanced activity. Furthermore, facilitated recovery rats, improving their autonomous capabilities test. These findings suggest promotes central

Язык: Английский

Neuromorphic algorithms for brain implants: a review DOI Creative Commons

Wiktoria Agata Pawlak,

Newton Howard

Frontiers in Neuroscience, Год журнала: 2025, Номер 19

Опубликована: Апрель 11, 2025

Neuromorphic computing technologies are about to change modern computing, yet most work thus far has emphasized hardware development. This review focuses on the latest progress in algorithmic advances specifically for potential use brain implants. We discuss current algorithms and emerging neurocomputational models that, when implemented neuromorphic hardware, could match or surpass traditional methods efficiency. Our aim is inspire creation deployment of that not only enhance computational performance implants but also serve broader fields like medical diagnostics robotics inspiring next generations neural

Язык: Английский

Процитировано

0

Visual light flicker stimulation: enhancing alertness in sleep-deprived rats DOI Creative Commons
Kun Wang, Kang Chen, Zilin Wei

и другие.

Frontiers in Neuroscience, Год журнала: 2024, Номер 18

Опубликована: Июнь 5, 2024

Introduction In the evolving field of neurophysiological research, visual light flicker stimulation is recognized as a promising non-invasive intervention for cognitive enhancement, particularly in sleep-deprived conditions. Methods This study explored effects specific frequencies (40 Hz and 20–30 random flicker) on alertness recovery rats. We employed multidisciplinary approach that included behavioral assessments with Y-maze, vivo electrophysiological recordings, molecular analyses such c-FOS immunohistochemistry hormone level measurements. Results Both 40 significantly enhanced performance Y-maze test, suggesting an improvement alertness. Neurophysiological data indicated activation neural circuits key brain areas like thalamus hippocampus. Additionally, exposure normalized cortisol serotonin levels, essential stress response mood regulation. Notably, increased expression regions related to functions suggested heightened activity. Discussion These findings underscore potential not only mitigate sleep deprivation but also enhance functions. The results pave way future translational research into light-based therapies human subjects, possible implications occupational health ergonomics.

Язык: Английский

Процитировано

0

An interpretable mechanism for grating-induced cross-inhibition and gamma oscillation based on a visual cortical neuronal network model DOI Creative Commons
Hao Yang,

Peihan Wang,

Fang Han

и другие.

Electronic Research Archive, Год журнала: 2024, Номер 32(4), С. 2936 - 2954

Опубликована: Янв. 1, 2024

<abstract><p>Biological experiments targeting the mammalian primary visual cortex have shown that neuronal response to a preferred orientation grating is cross-inhibited by an orthogonal mask grating. The plaid formed overlap of two gratings not only causes decrease in firing rate but also shifts gamma oscillation weaker at higher frequency. mechanism for above phenomena unclarified. In this paper, large-scale cortical network model with biological details constructed. model, modes connectivity may contribute cross-inhibition are considered: thalamo-cortical feedforward pathway and push-pull organization layer 4. Based on modulation stimulation successfully reproduced, which consistent suggests it leads cross-inhibition. Furthermore, our analysis spike clusters current fluctuations increase frequency during transition stimuli from modulating source synaptic inhibition local populations. Such results will help understand processing under multi-input integration.</p></abstract>

Язык: Английский

Процитировано

0

High-gamma frequency flash stimulation as a possible cognitive facilitator in rat pups DOI
Yu Fu, Qingfeng Zhai

Brain Research, Год журнала: 2024, Номер 1848, С. 149314 - 149314

Опубликована: Ноя. 15, 2024

Язык: Английский

Процитировано

0

Visual Light Flicker Stimulation: Promoting Central Fatigue Recovery in Sleep-Deprived Rats DOI
Kun Wang, Kang Chen, Zilin Wei

и другие.

Опубликована: Янв. 1, 2023

Fatigue and sleepiness are among the primary causes of human errors workplace accidents. The application potential light flicker, as a strong environmental stimulus, in combatting fatigue is considerable. present study aimed to investigate anti-central effect flicker (specifically, 40 Hz 20-30 flickers) on sleep-deprived rats. Both C-FOS-positive cell distribution vivo electrophysiology were utilized assess effects stimulation neural networks. Y maze test was employed spontaneous activity exploratory ability rats influenced by visual stimulation. Additionally, changes cortisol serotonin levels blood examined animals' physiological state. results indicate that flickering has significant various brain regions, such thalamus hippocampus, associated with alertness. Moreover, at induced an enrichment beta gamma while suppressing low-frequency theta activity, indicating enhanced activity. Furthermore, facilitated recovery rats, improving their autonomous capabilities test. These findings suggest promotes central

Язык: Английский

Процитировано

0