Comparative Effects of Cognitive Rehabilitation and Photobiomodulation on Drug Craving in Treatment-Seeking Opioid Addicts DOI
Sayena Hadadgar,

Javid Peimani,

Peyman Hassani‐Abharian

и другие.

Photobiomodulation Photomedicine and Laser Surgery, Год журнала: 2024, Номер 42(1), С. 54 - 65

Опубликована: Янв. 1, 2024

Background: Drug addiction refers to a maladaptive pattern of drug use that frequently leads substance abuse problems and accompanying cognitive behavioral symptoms. Among the crucial criteria addiction, craving stands out as potent factor contributing ongoing relapse following period abstinence. To date, there is no definitive method for eradicating opioid cravings. The introduction novel neurocognitive interventions, such rehabilitation photobiomodulation (PBM), into realm psychiatric treatments holds promise due parallels between other disorders. These innovative techniques offer potential value in addressing addiction. Objective: This study aimed assess compare efficacy PBM alleviating cravings among individuals undergoing treatment clinical settings. Methods: research used randomized trial chosen method. statistical population encompassed all clients receiving at clinics, selected through convenience sampling method, with α = 0.05 significance level an effect size 85%. Gpower software was utilized determine three equal groups. Sixty-three participants, each having mean total score higher than 3 5 on Desire Questionnaire (DDQ), were randomly assigned two experimental groups (n 21 each) control group 21). For assessment immediate periodic craving, DDQ Obsessive Compulsive Use Scale used. In low-level laser group, 810 nm wavelength continuous irradiation applied twice week distance 1 cm by prefrontal part brain duration 6 weeks (12 sessions). stop signal n-back tasks (comprising 12 sessions, lasting 30 min). Results: results demonstrated intervention significantly reduced both post-test follow-up phases compared group. Bonferroni post hoc test indicated more effective terms working memory (WM) inhibitory reducing (p < 0.05). Conclusions: While targeting WM effectively therapy proved be this regard.

Язык: Английский

Photons Induce Vesicular Exocytotic Release of Glutamate in a Power-Dependent Way DOI Open Access
Chiara Cervetto, Andrea Amaroli, Sarah Amato

и другие.

International Journal of Molecular Sciences, Год журнала: 2023, Номер 24(13), С. 10977 - 10977

Опубликована: Июль 1, 2023

Increasing evidence indicates that photobiomodulation, based on tissue irradiation with photons in the red to near-infrared spectrum, may be an effective therapeutic approach central nervous system disorders. Although functionality has been shown affected by animal models, as well preliminary healthy subjects or patients neuropsychiatric disorders, mechanisms involved photobiomodulation effects have not yet clarified. We previously observed could stimulate glutamate release. Here, we investigate potentially glutamate-releasing effect of from adult mouse cerebrocortical nerve terminals. report photon ability induce exocytotic vesicular release terminals glutamatergic neurons a power-dependent way. It can hypothesized depending potency, neurotoxic physiological range.

Язык: Английский

Процитировано

6

Photobiomodulation improves depression symptoms: a systematic review and meta-analysis of randomized controlled trials DOI Creative Commons

Qipei Ji,

Shichang Yan,

Ding Ji-lin

и другие.

Frontiers in Psychiatry, Год журнала: 2024, Номер 14

Опубликована: Янв. 31, 2024

Depression is a common mental illness that widely recognized by its lack of pleasure, fatigue, low mood, and, in severe cases, even suicidal tendencies. Photobiomodulation (PBM) non-invasive neuromodulation technique could treat patients with mood disorders such as depression. A systematic search ten databases, including randomized controlled trials (RCTs) for depression, was conducted from the time library construction to September 25, 2023. The primary outcome secondary sleep. Meta-analysis performed using RevMan (version 5.4) and Stata 14.0). Subgroup analyses were identify sources heterogeneity. certainty evidence assessed Grading Recommendations Assessment, Development, Evaluation (GRADE). Three thousand two hundred sixty-five studies retrieved database screened inclusion eleven trials. forest plot results demonstrated PBM alleviated depression (SMD = -0.55, 95% CI [-0.75, -0.35], I2 46%). But it not statistically significant patients' sleep outcomes -0.82, [-2.41, 0.77], 0%, p > 0.05). analysis showed s-PBM superior t-PBM relieving symptoms best improvement achieved wavelength 823 nm, fluence 10-100 J/cm2, irradiance 50-100 mW/cm2, 30 min, treatment frequency < 3/week, number treatments >15 times. 808 ≤1 ≤ 5 ≥ All had quality either moderate or very low, there no bias publication. We conclude effective reducing patients. However, current small, further are needed extend results. https://www.crd.york.ac.uk/PROSPERO/, CRD42023444677.

Язык: Английский

Процитировано

2

Advances in the transport of laser radiation to the brain with optical clearing: From simulation to reality DOI
Alaa Sabeeh Shanshool,

Saeed Ziaee,

Mohammad Ali Ansari

и другие.

Progress in Quantum Electronics, Год журнала: 2024, Номер 94, С. 100506 - 100506

Опубликована: Фев. 24, 2024

Язык: Английский

Процитировано

2

A Brief Review of Low-Level Light Therapy in Depression Disorder DOI Open Access
Afshan Shirkavand,

Maryam Akhavan Tavakoli,

Zeinab Ebrahimpour

и другие.

Journal of lasers in medical sciences, Год журнала: 2023, Номер 14, С. e55 - e55

Опубликована: Ноя. 11, 2023

Introduction: Low-level laser therapy (LLLT), also called Photobiomodulation, has gained widespread acceptance as a mainstream modality, particularly in the form of photobiostimulation (PBM). Here our review, we aim to present application LLLT help with depression, explore potential action mechanisms and pathways, discuss existing limitations, address challenges associated its clinical implementation. Methods: In biological systems, visible light wavelength range 400-700 nm activates photoreceptors involved vision circadian rhythm regulation. The near-infrared (NIR) 800-1100 exhibits superior tissue penetration capabilities compared light, which enables non-invasive various tissues. Results: By enhancing adenosine triphosphate (ATP) production using respiratory chain, is able enhance blood flow, reduce inflammation, support repair healing, stem cell growth proliferation. Preclinical studies animal models have shown promising neuroprotective effects method on central nervous system (CNS) diseases, suggesting improvements brain function for patients suffering from Alzheimer's disease. addition, it helps Parkinson's their movement problems ameliorates mental disorders individuals depression. Conclusion: patients' quality life can be significantly enhanced. A comprehensive understanding protective underlying will facilitate therapeutic future.

Язык: Английский

Процитировано

4

Comparative Effects of Cognitive Rehabilitation and Photobiomodulation on Drug Craving in Treatment-Seeking Opioid Addicts DOI
Sayena Hadadgar,

Javid Peimani,

Peyman Hassani‐Abharian

и другие.

Photobiomodulation Photomedicine and Laser Surgery, Год журнала: 2024, Номер 42(1), С. 54 - 65

Опубликована: Янв. 1, 2024

Background: Drug addiction refers to a maladaptive pattern of drug use that frequently leads substance abuse problems and accompanying cognitive behavioral symptoms. Among the crucial criteria addiction, craving stands out as potent factor contributing ongoing relapse following period abstinence. To date, there is no definitive method for eradicating opioid cravings. The introduction novel neurocognitive interventions, such rehabilitation photobiomodulation (PBM), into realm psychiatric treatments holds promise due parallels between other disorders. These innovative techniques offer potential value in addressing addiction. Objective: This study aimed assess compare efficacy PBM alleviating cravings among individuals undergoing treatment clinical settings. Methods: research used randomized trial chosen method. statistical population encompassed all clients receiving at clinics, selected through convenience sampling method, with α = 0.05 significance level an effect size 85%. Gpower software was utilized determine three equal groups. Sixty-three participants, each having mean total score higher than 3 5 on Desire Questionnaire (DDQ), were randomly assigned two experimental groups (n 21 each) control group 21). For assessment immediate periodic craving, DDQ Obsessive Compulsive Use Scale used. In low-level laser group, 810 nm wavelength continuous irradiation applied twice week distance 1 cm by prefrontal part brain duration 6 weeks (12 sessions). stop signal n-back tasks (comprising 12 sessions, lasting 30 min). Results: results demonstrated intervention significantly reduced both post-test follow-up phases compared group. Bonferroni post hoc test indicated more effective terms working memory (WM) inhibitory reducing (p < 0.05). Conclusions: While targeting WM effectively therapy proved be this regard.

Язык: Английский

Процитировано

1