Enhancing Acupuncture’s Efficacy in Chronic Stable Angina Through Standardization of Deqi Response and Dosage Parameters [Letter]
Journal of Pain Research,
Год журнала:
2025,
Номер
Volume 18, С. 553 - 554
Опубликована: Фев. 1, 2025
Язык: Английский
The Mechanism of Acupuncture Regulating Autophagy: Progress and Prospect
Biomolecules,
Год журнала:
2025,
Номер
15(2), С. 263 - 263
Опубликована: Фев. 11, 2025
Autophagy
plays
a
crucial
role
in
the
physiopathological
mechanisms
of
diseases
by
regulating
cellular
functions
and
maintaining
homeostasis,
which
has
garnered
extensive
attention
from
researchers
worldwide.
The
holistic
regulation
bidirectional
effects
acupuncture
can
modulate
autophagy,
promoting
or
restoring
homeostasis
body's
internal
environment
to
achieve
therapeutic
outcomes.
This
paper
systematically
reviews
research
progress
on
use
for
treating
various
via
autophagy
pathway,
summarizes
signal
pathways
related
analyzes
deficiencies
present
existing
research.
review
results
indicate
that
mechanism
action
dysfunction
is
reflected
changes
LC3,
Beclin1,
p53,
autophagy-associated
(ATG)
protein
expression,
regulates
signaling
key
proteins
genes.
regulatory
effect
capacity
bidirectional:
it
inhibits
abnormal
activation
prevent
exacerbation
injury
reduce
apoptosis,
while
also
activating
enhancing
promote
elimination
inflammation
oxidative
stress.
Further
analysis
suggests
are
insufficiently
explored.
Future
should
prioritize
development
more
appropriate
animal
models,
analyzing
accuracy
relevant
specificity
indicators,
exploring
synergistic
among
targets
pathways,
clarifying
at
stages
evaluating
efficacy
modulating.
offers
valuable
insights
into
acupuncture.
Язык: Английский
The efficacy and safety of auricular acupoint therapy on treating functional dyspepsia with insomnia: study protocol for a randomized controlled trial
Frontiers in Medicine,
Год журнала:
2025,
Номер
12
Опубликована: Март 12, 2025
Background
Functional
dyspepsia
(FD)
is
a
prevalent
health
issue
currently
lacking
optimal
treatment
options,
with
its
global
incidence
rate
increasing
in
recent
years.
Clinical
studies
have
recently
focused
on
the
application
of
auriculotherapy
functional
gastrointestinal
disorders
that
are
accompanied
by
negative
emotions.
However,
few
randomized
controlled
trials
investigated
use
for
FD
patients
insomnia,
leaving
therapeutic
efficacy
and
safety
largely
undefined.
This
study
aims
to
evaluate
clinical
treating
insomnia.
Methods
analysis
single-center,
trial
involving
80
Using
central
randomization
system,
subjects
randomly
assigned
auricular
acupressure
group
or
sham
at
1:1
ratio,
targeting
concha
region
earlobe
region.
The
primary
outcome
response
2
weeks,
secondary
outcomes
include
8
sleep
data
assessed
actigraphy,
modified
Dyspepsia
Symptom
Diary,
short
form-Nepean
Index,
Self-rated
Anxiety
Scale,
Depression
High
Arousal
Heart
Rate
Variability.
Efficacy
results
will
be
evaluated
baseline
weeks
after
treatment.
Adverse
events
monitored
throughout
observation
period.
Discussion
this
anticipated
validate
improving
symptoms
as
well
reducing
emotional
states.
registration
ClinicalTrials.gov
,
NCT06466044.
Registered
14th
May
2024,
https://register.clinicaltrials.gov
.
Язык: Английский
Investigating the Analgesic Mechanisms of Acupuncture for Cancer Pain: Insights From Multimodal Bioelectrical Signal Analysis
Journal of Pain Research,
Год журнала:
2025,
Номер
Volume 18, С. 1435 - 1450
Опубликована: Март 1, 2025
Cancer
pain
management
remains
a
significant
clinical
challenge.
While
acupuncture
has
shown
potential
in
alleviating
cancer
pain,
its
underlying
mechanisms
are
not
yet
fully
understood.
This
study
investigates
the
neurophysiological
acupuncture's
analgesic
effects
using
multimodal
bioelectrical
signal
analysis.
Fifteen
patients
underwent
while
wearing
portable,
multi-sensor
devices
to
capture
signals.
Pain
levels
were
assessed
Numerical
Rating
Scale
(NRS)
before
and
during
needle
retention.
Neurophysiological
changes
evaluated
Principal
Component
Analysis,
Joint
Time-Frequency
power
spectrum
analysis,
spectral
dynamic
functional
network
There
was
reduction
NRS
scores
from
pre-treatment
retention
period,
indicating
relief.
component
analysis
showed
differences
signals
between
these
periods.
Power
revealed
decreased
Functional
demonstrated
connectivity
strength
electroencephalography
electromyography
Spectral
identified
distinct
real-time
staged
characteristics
of
signals,
with
correlation
confirming
positive
relationship
score
alterations.
Acupuncture
alleviates
by
reducing
injured
tissues
brain,
immediate
effects.
Prolonging
may
enhance
therapeutic
outcomes.
These
findings
provide
new
insights
into
basis
effects,
supporting
role
management.
Язык: Английский
The majority of Norwegian patients with treatment-resistant chronic pain regained normal national health standards within 12 months after De-Qi acupuncture - a prospective observational propensity score matched study
Frontiers in Pain Research,
Год журнала:
2025,
Номер
6
Опубликована: Апрель 8, 2025
In
previous
studies,
acupuncture
was
effective
in
the
treatment
of
patients
with
chronic
pain
that
unresponsive
to
conventional
therapies.
However,
proportion
a
real-world
setting
who
regain
normal
health
after
1
year,
following
De-Qi
is
unknown.
This
an
observational
prospective
study
354
new
family
medical
practice
between
2015
and
2018.
Patients
self-assessed
using
Visual
Analogue
Scale
(VAS),
Short
Form
36
Health
Survey
(SF-36)
before
at
3-
12-months
follow-up.
VAS
SF-36
components
were
compared
for
improvements
therapeutic
effect
sizes.
Propensity
score
matching
employed
avoid
bias
by
confounding
variables.
The
participation
rate
29%,
median
age
50
years
(range
20-79),
65%
females,
duration
18
months
(6-360),
number
treatments
6
(1-27).
initial
intensity
6.2
(SD
2.5)
improved
4.0
3
3.2
12
(p
<
.001,
large
size);
scores
also
improved.
75%
showed
strong
responses,
58%
reaching
complete
cure
17%
achieving
near-normal
health.
aged
>65
responded
well
≥6
associated
stronger
responses
than
1-5.
Hill
criteria
analysis
suggested
causation
over
association.
(median
months),
treatments,
sustained
reduction
improvements.
Most
attained
Norwegian
national
standards
(complete
cure)
12-months.
Язык: Английский
Application and Development of Nanotechnology in Traditional Chinese Acupuncture in Recent 20 Years: A Comprehensive Review
ACS Applied Materials & Interfaces,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 8, 2025
Acupuncture,
rooted
in
Traditional
Chinese
Medicine
(TCM),
serves
as
a
complementary
and
alternative
therapeutic
modality
that
involves
the
insertion
of
needles
into
specific
body
points
to
stimulate
treat
variety
conditions.
Over
time,
acupuncture
has
garnered
global
acceptance,
progressively
addressing
an
increasing
spectrum
medical
disorders.
The
integration
nanotechnology
holds
considerable
potential
improve
drug
delivery
efficacy
broaden
scope
acupuncture's
applications,
providing
novel
opportunities
for
investigating
underlying
principles
meridians
acupoints.
A
bibliometric
analysis
application
over
past
two
decades
(2004-2024)
highlights
emerging
research
trends
focal
field.
This
article
provides
overview
history,
biological
mechanisms,
preparation
methods,
clinical
status
nanoacupuncture,
with
focus
on
analyzing
applications
nanoacupuncture
technology.
Nanotechnology
enables
visualization
imaging
acupoints,
facilitating
deeper
understanding
physiological
mechanisms
behind
effects.
Modified
incorporating
can
serve
dual
purposes:
functioning
sensors
real-time
monitoring
various
parameters,
thereby
supporting
disease
diagnosis
enhancing
through
specialized
interventions.
Furthermore,
nanotechnology-enhanced
act
platforms
targeted
working
tandem
responsive
nanoparticles
treatment.
Despite
its
promising
applicability,
faces
inherent
limitations
challenges
must
be
addressed.
Язык: Английский
Role of “Pressing Hand” in Acupuncture Treatment of Postherpetic Neuralgia
World Journal of Traditional Chinese Medicine,
Год журнала:
2025,
Номер
unknown
Опубликована: Май 8, 2025
Abstract
Postherpetic
neuralgia
is
a
neuropathic
pain
syndrome
commonly
observed
in
clinical
practice,
and
acupuncture
treatment
has
often
been
used
because
of
its
better
efficacy
fewer
adverse
reactions.
In
this
paper,
we
studied,
analyzed,
summarized
the
important
role
pressing
hand
entire
process
for
postherpetic
found
it
to
be
an
factor
improving
safety
acupuncture.
Clinicians
should
pay
attention
importance
synergistic
cooperation
between
needling
hands
further
optimize
Язык: Английский
Acupuncture at Weizhong (BL40) attenuates acetic acid-induced overactive bladder in rats by regulating brain neural activity through the modulation of mast cells and tibial nerves
Journal of Integrative Medicine,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 1, 2024
Язык: Английский