Special tea products featuring functional components: Health benefits and processing strategies

Comprehensive Reviews in Food Science and Food Safety, Год журнала: 2023, Номер 22(3), С. 1686 - 1721

Опубликована: Март 1, 2023

Abstract The functional components in tea confer various potential health benefits to humans. To date, several special products featuring (STPFCs) have been successfully developed, such as O ‐methylated catechin‐rich tea, γ‐aminobutyric acid‐rich low‐caffeine and selenium‐rich products. STPFCs some unique enhanced when compared with conventional products, which can meet the specific needs preferences of different groups huge market potential. processing strategies improve by regulating component content an active area research food science. fresh leaves varieties rich are used raw materials, technologies employed prepare STPFCs. Huge progress has achieved development these However, current status not yet systematically reviewed. Here, studies on comprehensively reviewed a focus their strategies. Additionally, other chemical be developed into teas application industry discussed. Finally, suggestions promises challenges for future study provided. This paper might shed light Future should screening varieties, identifying new components, evaluating health‐promoting effects, improving flavor quality, elucidating interactions between components.

Язык: Английский

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Role of Epigallocatechin Gallate in Selected Malignant Neoplasms in Women

Nutrients, Год журнала: 2025, Номер 17(2), С. 212 - 212

Опубликована: Янв. 8, 2025

Tea is a significant source of flavonoids in the diet. Due to different production processes, amount bioactive compounds unfermented (green) and (semi-)fermented tea differs. Importantly, green has similar composition phenolic fresh, unprocessed leaves. It consists primarily monomeric flavan-3-ols, known as catechins, which epigallocatechin gallate (EGCG) most abundant. Thanks its antioxidant, antiproliferative, antiangiogenic properties, EGCG attracted scientific community's attention potential use preventing and/or combating cancer. In this review article, we summarize literature reports found Google Scholar PubMed databases on anticancer effect selected malignant neoplasms women, i.e., breast, cervical, endometrial, ovarian cancers, have been published over last two decades. needs be emphasized that concentrations reported effective against cancer cells are typically higher than those plasma after polyphenol administration. Moreover, low bioavailability absorption appear main reasons for differences effects between vitro vivo studies. context, also decided look at possible solutions these problems, consisting combining with other components or using nanotechnology. Despite promising results studies conducted so far, mainly animal models, there no doubt further, broad-based activities necessary unequivocally assess oncological treatment combat women.

Язык: Английский

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Cancer Metabolism as a Therapeutic Target and Review of Interventions

Nutrients, Год журнала: 2023, Номер 15(19), С. 4245 - 4245

Опубликована: Окт. 1, 2023

Cancer is amenable to low-cost treatments, given that it has a significant metabolic component, which can be affected through diet and lifestyle change at minimal cost. The Warburg hypothesis states cancer cells have an altered cell metabolism towards anaerobic glycolysis. Given this reprogramming in cells, possible target cancers metabolically by depriving them of glucose. In addition dietary modifications work on tumors metabolically, there are panoply nutritional supplements repurposed drugs associated with prevention better treatment outcomes. These interventions their evidentiary basis covered the latter half review guide future treatment.

Язык: Английский

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The Effect of Brewing Time on the Antioxidant Activity of Tea Infusions

Applied Sciences, Год журнала: 2024, Номер 14(5), С. 2014 - 2014

Опубликована: Фев. 29, 2024

Many studies have found that tea has an antioxidant, anti-inflammatory, anti-cancer, anti-obesogenic and anti-diabetic effect, mostly associated with the content of anti-oxidant compounds. Polyphenols, being main secondary metabolites in tea, are often considered physiological markers determining a tea’s quality. Apart from production process components, brewing conditions can also influence levels antioxidants tea. This study aimed to verify whether time various types (5, 10 15 min) affects level extraction antioxidant compounds into infusions their activity. We examined 11 tea: green leaf bags, white black red yerba mate, raspberry butterfly pea flower (Clitoria ternatea) lychee plum hibiscus Total polyphenol (TPC), flavonoids anthocyanins content, as well determination antiradical capacity DPPH radical ABTS cation, were determined using spectrophotometric assays. Due activity infusions, optimum for (leaf bags), mate is min. Red should be ten minutes, it five minutes. The results refer temperature recommended by manufacturers.

Язык: Английский

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Therapeutic Implications of Dietary Polyphenols-Loaded Nanoemulsions in Cancer Therapy

ACS Applied Bio Materials, Год журнала: 2024, Номер 7(4), С. 2036 - 2053

Опубликована: Март 25, 2024

Cancer is one of the major causes death worldwide, even second foremost cause related to non-communicable diseases. cells typically possess several cellular and biological processes including, persistence, propagation, differentiation, death, expression cellular-type specific functions. The molecular picture carcinogenesis progression unwinding, it appears be a tangled combination occurring within between cancer their surrounding tissue matrix. Polyphenols are plant secondary metabolites abundant in fruits, vegetables, cereals, other natural sources. Natural polyphenols have implicated potential anticancer activity by various mechanisms involved antitumor action, including modulation signaling pathways majorly proliferation, relocation, angiogenesis, metastatic processes, cell death. applications been limited due hydrophobic nature lower oral bioavailability that could possibly overcome through encapsulating them into nanocarrier-mediated delivery systems, leading improved activity. Nanoemulsions (NEs) diverse feasible properties, greater surface area, modifiable surficial charge, higher half-life, site-specific targeting, formulation imaging capability necessary create practical therapeutic impact, drawn increased attention therapy research. This review has summarized discussed basic concepts, classification, approaches, mechanism polyphenols-encapsulated nanoemulsions with therapy.

Язык: Английский

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Antitumor and Antioxidant Activities of In Vitro Cultivated and Wild-Growing Clinopodium vulgare L. Plants

Plants, Год журнала: 2023, Номер 12(8), С. 1591 - 1591

Опубликована: Апрель 9, 2023

Clinopodium vulgare L. is a valuable medicinal plant used for its anti-inflammatory, antibacterial and wound-healing properties. The present study describes an efficient protocol the micropropagation of C. compares, first time, chemical content composition antitumor antioxidant activities extracts from in vitro cultivated wild-growing plants. best nutrient medium was found to be Murashige Skoog (MS) supplemented with 1 mg/L BAP 0.1 IBA mg/L, yielding on average 6.9 shoots per nodal segment. Flower aqueous plants had higher total polyphenol (29,927.6 ± 592.1 mg/100 g vs. 27,292.8 85.3 g) ORAC activity (7281.3 82.9 µmol TE/g 7246.3 62.4 TE/g) compared flowers wild HPLC detected qualitative quantitative differences phenolic constituents between plants' extracts. Rosmarinic acid major constituent, being accumulated mainly leaves, while neochlorogenic compound Catechin only plants, but not or stems. Aqueous both showed significant against human HeLa (cervical adenocarcinoma), HT-29 (colorectal adenocarcinoma) MCF-7 (breast cancer) cell lines. cytotoxic most cancer lines, combined least detrimental effects non-tumor keratinocyte line (HaCaT), shown by leaf (250 µg/mL) flower (500 making source bioactive compounds suitable candidate anticancer therapy.

Язык: Английский

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Trends of caffeine intake from food and beverage among Chinese adults: 2004–2018

Food and Chemical Toxicology, Год журнала: 2023, Номер 173, С. 113629 - 113629

Опубликована: Янв. 20, 2023

Язык: Английский

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Determination and quality evaluation of active ingredients in areca nut using near-infrared rapid detection technology

Microchemical Journal, Год журнала: 2023, Номер 196, С. 109586 - 109586

Опубликована: Ноя. 1, 2023

Язык: Английский

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Unveiling the phytochemical profiles, selective bioactivity potential, and molecular docking study of bioactive compounds with target proteins using optimized bark extracts of Grewia asiatica L.

Kuwait Journal of Science, Год журнала: 2024, Номер 51(3), С. 100230 - 100230

Опубликована: Апрель 12, 2024

The current study aimed to explore the phytochemicals, estimate anti-inflammatory, antioxidant, antimicrobial, and anticancer potentials of polyphenol enriched methanolic bark extract Grewia asiatica (PEMGa), perform molecular docking studies with identified phytocompounds. Here, we utilized response surface methodology (RSM) a Box Behnken design (BBD) enhance phenolic content from G. by optimizing three crucial parameters like extraction time (h.), temperature (°C), solvent ratio (% v/v methanol: water). Phytochemical quantification PEMGa illustrated that part contains good amount therapeutically potent phytochemical groups phenolics, flavonoids, tannins. Additionally, through HPLC analysis, eight compounds belonging flavonoid have been quantified PEMGa. By GC-MS (Gas chromatography–mass spectrometry) analysis PEMGa, eleven phytochemicals were identified. Moreover, employing in-vitro bioactivity studies, has unveiled its remarkable potential as an agent. During in-silico study, out phytocompounds compounds, namely, γ-sitosterol, stigmasterol, campesterol, formed most stable docked complex antioxidant target proteins. present provides justification for rich source against oxidative stresses, inflammations, cancer, microbial infections.

Язык: Английский

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Targeting Tumor Hypoxia with Nanoparticle-Based Therapies: Challenges, Opportunities, and Clinical Implications

Pharmaceuticals, Год журнала: 2024, Номер 17(10), С. 1389 - 1389

Опубликована: Окт. 18, 2024

Hypoxia is a crucial factor in tumor biology, affecting various solid tumors to different extents. Its influence spans both early and advanced stages of cancer, altering cellular functions promoting resistance therapy. reduces the effectiveness radiotherapy, chemotherapy, immunotherapy, making it target for improving therapeutic outcomes. Despite extensive research, gaps persist, necessitating exploration new chemical pharmacological interventions modulate hypoxia-related pathways. This review discusses complex pathways involved hypoxia associated pharmacotherapies, highlighting limitations current treatments. It emphasizes potential nanoparticle-based platforms delivering anti-hypoxic agents, particularly oxygen (O

Язык: Английский

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