The Efficacy of Mediterranean Diet for Erectile Dysfunction in Diabetes Mellitus Patients: A Narrative Review DOI Creative Commons
Maxwell Salvador Surya Atmaja,

Michael Purnama,

Kevin Kevin

и другие.

Indonesian Andrology and Biomedical Journal, Год журнала: 2024, Номер 5(1), С. 34 - 41

Опубликована: Июнь 27, 2024

Background : Male infertility affects millions globally, with 12-15% of Indonesian couples facing conception challenges, 50% which are attributed to male factors. Despite extensive research, 70% cases remain idiopathic. Diabetes, a prominent factor in infertility, 9.3% the global population, projections estimating 700 million by 2045. Recent studies suggest Mediterranean diet positively impacts semen parameters, particularly diabetic individuals. This review aims explore diet's effects on fertility patients. Reviews The literature employed three databases, focusing in-vitro, in-vivo, pre-clinical, and clinical from 2014-2024. chronic disease characterized abnormal blood sugar levels, insulin production or effectiveness, leading complications if left uncontrolled. Erectile dysfunction (ED), prevalent men, is nerve vessel damage high levels. Treatments for ED include PDE5 inhibitors, but alternative plant-based therapies being explored. Platelet-rich plasma (PRP) has shown promise animal lacks human trial data. diet, rich foods healthy fats, may help prevent sexual function deterioration Comprehensive nutrition education government efforts crucial promoting lifestyles ensuring access fresh foods. Summary In conclusion, shows as dietary intervention improving populations. Further research warranted confirm these findings mechanisms underlying fertility.

Язык: Английский

Oxidative Stress-Associated Male Infertility: Current Diagnostic and Therapeutic Approaches DOI Creative Commons

Haritha Pavuluri,

Zahra Bakhtiary, Manesh Kumar Panner Selvam

и другие.

Medicina, Год журнала: 2024, Номер 60(6), С. 1008 - 1008

Опубликована: Июнь 20, 2024

Infertility is a prevalent global issue affecting approximately 17.5% of adults, with sole male factor contributing to 20–30% cases. Oxidative stress (OS) critical in infertility, disrupting the balance between reactive oxygen species (ROS) and antioxidants. This imbalance detrimentally affects sperm function viability, ultimately impairing fertility. OS also triggers molecular changes sperm, including DNA damage, lipid peroxidation, alterations protein expression, further compromising functionality potential fertilization. Diagnostic tools discussed this review offer insights into markers, antioxidant levels, intracellular ROS concentrations. By accurately assessing these parameters, clinicians can diagnose infertility more effectively thus tailor treatment plans individual patients. Additionally, explores various options for males OS-associated such as empirical drugs, antioxidants, nanoantioxidants, lifestyle modifications. addressing root causes implementing targeted interventions, optimize outcomes enhance chances conception couples struggling infertility.

Язык: Английский

Процитировано

11
Adherence to the Mediterranean Diet for a Better Sperm Quality: A Comprehensive Systematic Review and Meta-Analysis DOI Open Access

Abdul Munawwir,

Zalsabila Tiara Adhani

Jurnal Gizi dan Pangan, Год журнала: 2025, Номер 20(1), С. 61 - 70

Опубликована: Март 31, 2025

The aim of this study is to investigate whether a higher adherence the Mediterranean Diet (MD) can enhance reproductive indicators in infertile men. A comprehensive review and meta-analysis were conducted assess increased MD An extensive search was for pertinent studies PubMed, Medline, Google Scholar. included relevant publications published last 10 years from 2015. Preferred Reporting Items Systematic Review Meta-analysis (PRISMA) 2020 instrument used evaluate studies. study's quality evaluated using Newcastle-Ottawa Scale (NOS). data analyzed RevMan version 5.4.1. on sperm volume not statistically significant. indicated an odds ratio 1.06 low semen (<1.5 mL) associated with (I2=12%; 95% CI:0.59–1.93, p=0.84). Furthermore, analysis revealed 2.86-fold increase probability achieving concentration (>15 × 106/mL) individuals who adhered (I2=33%; CI:1.58–5.18, p=0.0005). further suggests that 2.54-fold likelihood improving count (>39 106/ejaculate) (I2=48%; OR=2.54; CI:1.32–4.90, p=0.005). motility demonstrated adhere strictly are more likely exhibit normal (>40%) (I2=0%; OR=4.64; CI:2.41–8.95, p<0.00001). 2.66-fold better morphology (>4%) OR=2.66; CI:1.39–5.10, p=0.003) adhering MD. present systematic indicates improved parameters (sperm count, concentration, motility, morphology).

Язык: Английский

Процитировано

0
Can lifestyle changes significantly improve male fertility: A narrative review? DOI Creative Commons
Kadir Böcü, Luca Boeri, Asli Metin Mahmutoglu

и другие.

Arab Journal of Urology, Год журнала: 2024, Номер unknown, С. 1 - 11

Опубликована: Ноя. 1, 2024

Male infertility is increasingly recognized as a significant global health concern, with lifestyle factors being critical contributors to declining male fertility rates. This narrative review comprehensively analyzes the impact of various choices, including diet, physical activity, substance use, stress, sleep, weight management, sexual habits, and environmental occupational exposures on reproductive health. The examines biological ecological mechanisms through which these affect spermatogenesis sperm quality. Furthermore, it discusses potential interventions, such dietary modifications, management strategies, cessation programs, stress reduction techniques, workplace policy changes improve outcomes. Emphasis placed role oxidative hormonal regulation, DNA integrity in mediating effects factors. While modifications can significantly enhance health, available evidence highlights need for more rigorous research establish solid guidelines interventions mitigating infertility.

Язык: Английский

Процитировано

1
The Efficacy of Mediterranean Diet for Erectile Dysfunction in Diabetes Mellitus Patients: A Narrative Review DOI Creative Commons
Maxwell Salvador Surya Atmaja,

Michael Purnama,

Kevin Kevin

и другие.

Indonesian Andrology and Biomedical Journal, Год журнала: 2024, Номер 5(1), С. 34 - 41

Опубликована: Июнь 27, 2024

Background : Male infertility affects millions globally, with 12-15% of Indonesian couples facing conception challenges, 50% which are attributed to male factors. Despite extensive research, 70% cases remain idiopathic. Diabetes, a prominent factor in infertility, 9.3% the global population, projections estimating 700 million by 2045. Recent studies suggest Mediterranean diet positively impacts semen parameters, particularly diabetic individuals. This review aims explore diet's effects on fertility patients. Reviews The literature employed three databases, focusing in-vitro, in-vivo, pre-clinical, and clinical from 2014-2024. chronic disease characterized abnormal blood sugar levels, insulin production or effectiveness, leading complications if left uncontrolled. Erectile dysfunction (ED), prevalent men, is nerve vessel damage high levels. Treatments for ED include PDE5 inhibitors, but alternative plant-based therapies being explored. Platelet-rich plasma (PRP) has shown promise animal lacks human trial data. diet, rich foods healthy fats, may help prevent sexual function deterioration Comprehensive nutrition education government efforts crucial promoting lifestyles ensuring access fresh foods. Summary In conclusion, shows as dietary intervention improving populations. Further research warranted confirm these findings mechanisms underlying fertility.

Язык: Английский

Процитировано

0