Insights into Q-marker of Shensong Yangxin capsule in treating cardiac arrhythmias based on a linear substitution strategy in quantification of multiple components

Phytomedicine, Год журнала: 2025, Номер 138, С. 156382 - 156382

Опубликована: Янв. 13, 2025

Язык: Английский

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Perspectives on Berberine and the Regulation of Gut Microbiota: As an Anti-Inflammatory Agent

Pharmaceuticals, Год журнала: 2025, Номер 18(2), С. 193 - 193

Опубликована: Янв. 31, 2025

Berberine is a promising agent for modulating the intestinal microbiota, playing crucial role in human health homeostasis. This natural compound promotes growth of beneficial bacteria such as Bacteroides, Bifidobacterium, and Lactobacillus while reducing harmful Escherichia coli. Clinical preclinical studies demonstrate that helps regulate T2D metabolic disorders, improves blood glucose levels during T2D, reduces lipid profile chronic inflammation, especially when combined with probiotics. represents adjuvant therapy inflammatory diseases, particularly due to its multifaceted actions inhibiting proinflammatory cytokines pathways IBS, IBD, UC modulation gut microbiota and/or enhancement integrity epithelial barrier. review establishes basis future treatment protocols berberine fully elucidates mechanisms.

Язык: Английский

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Causal Relationship of Familial Hypercholesterolemia with Risk of Intestinal Vascular Disorders: A Mendelian Randomization Study

Metabolism Open, Год журнала: 2025, Номер 25, С. 100352 - 100352

Опубликована: Фев. 1, 2025

Язык: Английский

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Demystifying the Potential of Polymeric Lipids as Substitute in Regenerative Applications: A Review

Polymers for Advanced Technologies, Год журнала: 2025, Номер 36(2)

Опубликована: Фев. 1, 2025

ABSTRACT The objective of a regenerative medicine is to repair, restore, and regenerate tissues organs that occurred due injury or defect disease. Additionally, the purpose reverse aging process body by utilizing body's innate healing ability. There still significant venture needs be directed for advancement in arena medicine, which makes use products derived from cell therapy as well biomedical. Stem cells growth factors are primary components medicine; hence, novel drug delivering systems now being studied augment transport active pharmaceuticals. Lipid‐based complexed with therapeutics suited site‐specific controlled release. Lipids biocompatible available various sources molecular weights self‐assemble into forms hydrophilic hydrophobic parts. By enhancing plasma membrane fluidity, excipients such non‐ionic surfactants, fatty acids, glycerides increase permeability. Liposomes, nanoparticles, nano‐emulsions, micelles nano‐lipid carriers can improve bioavailability both lipophilic medicines. lipoidal‐polymeric had emerged promising multifaceted application cytocompatibility, ecofriendly, ability encapsulate variety drugs. Further, treatment biomedical tissue engineering, rapidly developing discipline. Furthermore, similar vein, delivery technologies combined stem promote engraftment, differentiation, survival. Hence colloidal carrier has impending versatile applications. Therefore, review offer an abridged information on significance technology offering confined ecosystem facilitates them thrive distinguish effective manner.

Язык: Английский

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The Many Facets of PPAR-γ Agonism in Obesity and Associated Comorbidities: Benefits, Risks, Challenges, and Future Directions

Current Obesity Reports, Год журнала: 2025, Номер 14(1)

Опубликована: Фев. 12, 2025

Язык: Английский

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