Anti-Inflammatory Effects of Peripheral Dopamine

International Journal of Molecular Sciences, Год журнала: 2023, Номер 24(18), С. 13816 - 13816

Опубликована: Сен. 7, 2023

Dopamine is synthesized in the nervous system where it acts as a neurotransmitter. also number of peripheral organs well several types cells and has organ-specific functions and, demonstrated more recently, involved regulation immune response inflammatory reaction. In particular, renal dopaminergic very important sodium transport blood pressure particularly sensitive to stimuli that cause oxidative stress inflammation. This review focused on how dopamine tissues mechanisms by which its receptors exert their effects response.

Язык: Английский

Research progress on the roles of dopamine and dopamine receptors in digestive system diseases

Journal of Cellular and Molecular Medicine, Год журнала: 2024, Номер 28(7)

Опубликована: Март 17, 2024

Dopamine (DA) is a neurotransmitter synthesized in the human body that acts on multiple organs throughout body, reaching them through blood circulation. Neurotransmitters are special molecules act as messengers by binding to receptors at chemical synapses between neurons. As ligands, they mainly bind corresponding central or peripheral tissue cells. Signalling involved regulating activities of various systems. Lack DA decrease levels brain can lead serious diseases such Parkinson's disease, schizophrenia, addiction and attention deficit disorder. It widely recognized closely related neurological diseases. research roles brain-gut peptides physiology pathology has deepened recent years, regulatory role neurotransmitters digestive system gradually attracted researchers' attention, expanded field This review elaborates progress DRs Starting from biochemical pharmacological properties DRs, it discusses therapeutic value DA- DR-related drugs for

Язык: Английский

The dopamine receptor agonist rotigotine attenuated indomethacin-induced enteropathy in the small intestinal mucosa of mice

Molecular Biology Reports, Год журнала: 2025, Номер 52(1)

Опубликована: Март 24, 2025

Язык: Английский