Опубликована: Март 20, 2025
Язык: Английский
Frontiers in Nutrition, Год журнала: 2022, Номер 9
Опубликована: Дек. 6, 2022
The potential of edible mushrooms as an unexploited treasure trove, although rarely included in known food guidelines, is highlighted. Their role shielding people against the side effects unhealthy stylish diet reviewed. Mushrooms complement human with various bioactive molecules not identified or deficient foodstuffs plant and animal sources, being considered a functional for prevention several diseases. have been widely used medicinal products more than 2,000 years, but globally field use wild has untapped. There broad range which remain poorly even unreported valuable pool sources compounds biopharma utilization new dietary supplements. Some unique elements their preventative healthcare are emphasized, through positive impact on immune system. antiviral, anti-inflammatory, anti-neoplastic, other health concerns discussed. incorporate top non-digestible oligosaccharides, ergothioneine, humans unable to synthesize, later antioxidant, cytoprotective, anti-inflammatory element, therapeutic potential, approved by world agencies. prebiotic activity beneficially affects gut homeostasis performance balance microbiota enhanced. Several recent studies neurological contribution growth nerve brain cells mentioned. Indeed, foods' nutraceuticals presently regarded next-generation foods, supporting wellness, promising prophylactic agents.
Язык: Английский
Процитировано
87
Food Chemistry Advances, Год журнала: 2023, Номер 3, С. 100375 - 100375
Опубликована: Июль 5, 2023
The aim of this study was to produce biscuit from blend mushroom flour and wheat flour. composite at 0, 10, 20, 30 40% level inclusion. analyzed for proximate composition, physical properties, mineral content, antioxidant carbohydrate inhibitory enzyme activities, glycemic index, trend in blood glucose concentration, microbiological sensory evaluation. Result the analysis showed that as proportion increased protein con also increased. content ranged 10.36 17.92 % while ash 0.63 3.31%. properties spread ratio with increase incorporation result revealed sodium calcium activities inhibited key digestive enzymes such (α- amylase α- glucosidase). index possessed low load. concentration rats fed increasing has a positive effect lower postprandial response WFMRB4 being lowest. microbial count 2 × 102 5.0 Cfu/g bacteria 1.0×102 3.0 cfu/g mould count. E coli not detected biscuit. Sensory evaluation biscuits were rated above average. can therefore be used manage diabetes mellitus overcome protein-energy deficiency.
Язык: Английский
Процитировано
42
Food Research International, Год журнала: 2023, Номер 173, С. 113223 - 113223
Опубликована: Июль 6, 2023
Язык: Английский
Процитировано
34
International Journal of Biological Macromolecules, Год журнала: 2024, Номер 266, С. 130893 - 130893
Опубликована: Март 16, 2024
Язык: Английский
Процитировано
11
RSC Advances, Год журнала: 2024, Номер 14(14), С. 10039 - 10055
Опубликована: Янв. 1, 2024
African swine fever virus (ASFV) has emerged as a serious threat to the pork industry resulting in significant economic losses and heightened concerns about food security. With no known cure presently available, existing control measures center on animal quarantine culling. Considering severity challenges posed by ASFV, it is imperative discover new treatment strategies implement additional prevent its further spread. This study recognized potential of 1830 fungal metabolites from medicinal fungi antiviral compounds against base excision repair (BER) proteins specifically
Язык: Английский
Процитировано
8
Foods, Год журнала: 2025, Номер 14(5), С. 741 - 741
Опубликована: Фев. 22, 2025
Mushrooms are known to be a nutritional powerhouse, offering diverse bioactive compounds that promote and enhance health. provide distinguishable taste aroma an essential source of vitamin D2, B complex, hydroxybenzoic acids (HBAs) hydroxycinnamic (HCAs), terpenes, sterols, β-glucans. Edible mushroom varieties such as Hericium erinaceus, Ganoderma sp., Lentinula edodes recognized functional foods due their remarkable potential for disease prevention promotion overall health well-being. These have antioxidants, anti-inflammatory, cytoprotective, cholesterol-lowering, antidiabetic, antimicrobial, anticancer properties, well controlling blood pressure, being immunity booster, strengthening bone properties. In addition, they contain non-digestible oligosaccharides (NDOs) ergothioneine, substrate gut microflora. Supplementing our daily meals with those can add value food, providing benefits. Novel edible mushrooms investigated explore substances therapeutic benefit human The scientific community (mycologists) is currently studying the prospects unlocking full advantages mushrooms. This review aims knowledge culturing conditions, potential, value-added products 11 varieties.
Язык: Английский
Процитировано
1
Fitoterapia, Год журнала: 2023, Номер 172, С. 105681 - 105681
Опубликована: Сен. 23, 2023
Resistance to apoptosis stands as a roadblock the successful pharmacological execution of anticancer drug effect. A comprehensive insight into apoptotic signaling pathways and an understanding mechanisms resistance are crucial unveil new targets. At this juncture, researchers heading towards natural sources in particular, mushroom their potential drugs leads being reliable source potent bioactive compounds. Given continuous increase cancer cases, efficacy mushrooms has inevitably become fascinating object due higher safety margin multitarget. This review aimed collect summarize all available scientific data on with from extracts molecules order suggest attributes via mitochondrion -mediated intrinsic mechanism. Compiled revealed that components including polysaccharides, sterols terpenoids well prepared using 15 different solvents 53 species could be effective supportive treatment 20 various cancers. The underlying therapeutic studied explored through diverse complementary investigations: vitro assays, pre-clinical studies clinical randomized controlled trials. processes mainly involved were ROS production, mitochondrial membrane dysfunction, action caspase 3, 9, XIAP, cIAP, p53, Bax, Bcl-2. In summary, study provides facts pertaining beneficial effect active compounds against types is shedding light targeted pathways.
Язык: Английский
Процитировано
20
New Zealand Journal of Botany, Год журнала: 2024, Номер unknown, С. 1 - 85
Опубликована: Июль 22, 2024
Ganoderma, a genus of mushrooms known for its long history medicinal use, has gained increasing attention in recent years due to potential health benefits. This review delves into the bioactive compounds found Ganoderma and elucidates intricate mechanisms underlying immunomodulatory anti-tumour activities. The diverse health-promoting effects can be attributed decadent array compounds, notably polysaccharides, triterpenoids, which play pivotal role. ability mushroom modulate immune system, enhancing activity cells, such as natural killer cells macrophages, is central focus. Furthermore, we explore how exerts through induction apoptosis, inhibition angiogenesis, interference with various signalling pathways critical cancer cell growth metastasis. As research this area continues evolve, comprehensive understanding supplement role promoting well-being emerging, offering promising avenues further investigation application healthcare.
Язык: Английский
Процитировано
6
Applied Microbiology and Biotechnology, Год журнала: 2023, Номер 107(16), С. 5035 - 5049
Опубликована: Июль 6, 2023
Язык: Английский
Процитировано
14
ACS Omega, Год журнала: 2023, Номер 8(3), С. 3102 - 3113
Опубликована: Янв. 10, 2023
Medicinal fungi, including mushrooms, have well-documented therapeutic uses. In this study, we perform a cheminformatics-based investigation of the scaffold and structural diversity secondary metabolite space medicinal fungi and, moreover, detailed comparison with approved drugs, other natural product libraries, semi-synthetic libraries. We find that has similar or higher in to libraries analyzed here. Notably, 94% scaffolds are not present drugs. Further, metabolites, on one hand, structurally far from while, they close terms molecular properties Lastly, chemical visualization using dimensionality reduction methods showed minimal overlap drug space. nutshell, our results underscore is valuable resource for identifying potential lead molecules product-based discovery.
Язык: Английский
Процитировано
11