Chemical Physics Reviews,
Год журнала:
2024,
Номер
5(4)
Опубликована: Дек. 1, 2024
In
recent
years,
chiral
semiconductor
nanocrystals
(NCs)
have
attracted
extensive
interest
from
researchers
and
significant
research
progress
has
been
made.
order
to
provide
with
a
comprehensive
in-depth
perspective
in
this
topic,
review
will
summarize
the
NCs,
including
synthesis
methods,
mechanism,
relevant
application.
First,
discuss
construction
strategies
of
various
NCs.
Second,
optical
activities
different
types
such
as
circular
dichroism
circularly
polarized
luminescence,
be
analyzed
depth,
origins
discussed
at
microscopic
level.
Third,
we
applications
NCs
optoelectronic
devices,
nonlinear
optics,
biomedicine.
Finally,
opportunities
challenges
study
Pharmaceutics,
Год журнала:
2025,
Номер
17(1), С. 70 - 70
Опубликована: Янв. 7, 2025
Malignant
growth
is
expected
to
surpass
other
significant
causes
of
death
as
one
the
top
reasons
for
dismalness
and
mortality
worldwide.
According
a
World
Health
Organization
(WHO)
study,
this
illness
approximately
between
9
10
million
instances
deaths
annually.
Chemotherapy,
radiation,
surgery
are
three
main
methods
treating
cancer.
These
seek
completely
eradicate
all
cancer
cells
while
having
fewest
possible
unintended
impacts
on
healthy
cell
types.
Owing
lack
target
selectivity,
majority
medications
have
substantial
side
effects.
On
hand,
nanomaterials
transformed
identification,
diagnosis,
management
Nanostructures
with
biomimetic
properties
been
grown
late,
fully
intent
observing
sickness.
nanostructures
be
consumed
by
in
areas
profound
disease.
Furthermore,
because
their
extraordinary
physicochemical
properties,
which
incorporate
nanoscale
aspects,
more
prominent
surface
region,
explicit
geometrical
features,
ability
embody
different
substances
within
or
outside
surfaces,
remarkable
nano-vehicles
conveying
restorative
specialists
designated
regions.
This
review
discusses
recent
developments
nanostructured
materials
such
graphene,
dendrimers,
cell-penetrating
peptide
nanoparticles,
nanoliposomes,
lipid
magnetic
nano-omics
diagnosis
International Journal of Newgen Research in Pharmacy & Healthcare,
Год журнала:
2024,
Номер
unknown, С. 30 - 41
Опубликована: Июнь 30, 2024
The
integration
of
Artificial
Intelligence
(AI)
and
Machine
Learning
(ML)
into
pharmaceutical
formulation
design
has
brought
about
a
significant
transformation,
opening
up
new
avenues
for
innovation
operational
efficiency.
This
review
paper
aims
to
extensively
examine
the
utilization
AI
ML
in
development,
consolidating
recent
empirical
findings
emerging
patterns.
Meta-analyses
examining
AI-driven
drug
discovery
efforts
have
revealed
promising
outcomes,
including
acceleration
development
timelines
enhancements
success
rates
across
preclinical
clinical
trials.
Notably,
meta-analysis
featured
Nature
Reviews
Drug
Discovery
sheds
light
on
pivotal
role
rational
design,
resulting
identification
novel
therapeutic
candidates
boasting
improved
efficacy
diminished
side
effects.
Furthermore,
techniques
are
increasingly
being
deployed
optimize
delivery
systems,
with
studies
showcasing
their
effectiveness
devising
controlled-release
formulations
nano-scale
platforms.
For
instance,
research
highlighted
Advanced
Delivery
demonstrates
application
algorithms
predicting
physicochemical
attributes
nanoparticles,
thereby
aiding
more
durable
efficient
carriers.
Despite
these
advancements,
challenges
persist,
data
scarcity,
regulatory
complexities,
ethical
considerations.
Nevertheless,
ongoing
endeavors
tackle
obstacles
coupled
continual
evolution
technologies
offer
prospects
future
design.
In
conclusion,
this
underscores
transformative
influence
underscoring
necessity
sustained
collaboration
fully
leverage
enhancing
healthcare
outcomes.
International Journal of Breast Cancer,
Год журнала:
2025,
Номер
2025(1)
Опубликована: Янв. 1, 2025
Breast
cancer
stands
as
the
utmost
prevalent
malignancy
in
women,
impacting
epithelial
tissue
of
breast
and
often
displaying
resistance
to
effective
treatment
due
its
diverse
molecular
histological
features.
Current
modalities
may
exhibit
decreasing
efficacy
over
time
can
lead
disease
progression.
The
mitochondria,
a
crucial
organelle
responsible
for
cellular
metabolism
energy
supply,
stand
highly
sensitive
both
heat
reactive
oxygen
species,
presenting
an
assuring
target
photodynamic
photothermal
therapies
(PTTs)
cure.
employment
nanodrug
carriers
combination
deliveries
holds
promise
addressing
challenges
related
drug
degradation
off-target
toxicity.
By
circumventing
reticuloendothelial
system,
nanocarriers
bolster
drug's
bioavailability
at
intended
site
ensure
controlled
codelivery
multiple
drugs,
thereby
maintaining
normal
pharmacokinetic
features
regular
pharmacodynamic
characteristics
different
therapeutic
mechanisms.
precision
this
innovative
technology
have
revolutionized
delivery,
substantially
enhancing
effectiveness.
In
pursuit
targeting
mitochondrial
modifications
cells,
various
such
therapy
(PDT),
PTT,
chemodynamic
(CDT)
been
explored.
These
improved
efficiency
mitochondria-targeted
their
advantageous
properties
minimal
toxicity,
noninvasiveness,
reduced
resistance,
safer
profile.
Our
review
article
provides
exhaustive
overview
alterations
environment
BC,
impact
on
BC
development,
potential
targets
treatment,
nanotherapeutic
approaches
limitations
these
approaches.
