IGF2BP1/AIFM2 axis regulates ferroptosis and glycolysis to drive hepatocellular carcinoma progression

Cellular Signalling, Год журнала: 2025, Номер unknown, С. 111660 - 111660

Опубликована: Фев. 1, 2025

Язык: Английский

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Bibliometric analysis and research trends in minimum quantity lubrication for reducing cutting forces

The International Journal of Advanced Manufacturing Technology, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 21, 2024

Язык: Английский

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Ginseng and its functional components in non-alcoholic fatty liver disease: therapeutic effects and multi-target pharmacological mechanisms

Frontiers in Pharmacology, Год журнала: 2025, Номер 16

Опубликована: Апрель 9, 2025

Non-alcoholic fatty liver disease (NAFLD) is a common type of chronic and its incidence increasing. Its progression closely related to non-alcoholic steatohepatitis fibrosis. Effective treatment currently lacking. The traditional Chinese medicine ginseng (Panax ginseng) shows unique advantages in NAFLD intervention, but complex compositional system molecular mechanism network still need be systematically analyzed. This paper integrates evidence from nearly 20 years research elucidate the multi-target pharmacological for NAFLD. Relevant information was sourced Pubmed, Web science, Embase CNKI databases. Using BioRender visio draw biomedical illustrations. active ingredients contain 2 classes saponins (tetracyclic triterpene saponins, pentacyclic other modified types) non-saponins. Different cultivation methods, processing techniques extraction sites have expanded variety constituents demonstrated different activities. Studies shown that functional components ability regulate lipid metabolism disorders, inflammation, oxidative stress, endoplasmic reticulum insulin resistance, disruption intestinal flora structure, cell death senescence. Demonstrates potential study reveals first time integrative through tertiary mode action "multi-component multi-pathway". multilevel modulatory provides new direction development comprehensive therapeutic strategies

Язык: Английский

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The glycolytic characteristics of hepatocellular carcinoma and its interaction with the microenvironment: a comprehensive omics study

Journal of Translational Medicine, Год журнала: 2025, Номер 23(1)

Опубликована: Апрель 10, 2025

Язык: Английский

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Targeting c-MYC has a Key Role in Hepatocellular Carcinoma Therapy

Critical Reviews in Oncology/Hematology, Год журнала: 2025, Номер unknown, С. 104786 - 104786

Опубликована: Июнь 1, 2025

Язык: Английский

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