Role of Microbiota‐Derived Metabolites in Prostate Cancer Inflammation and Progression DOI Open Access
Pradeep Kumar Rathinavelu, Anil Kumar, Virendra Kumar

и другие.

Cell Biochemistry and Function, Год журнала: 2025, Номер 43(2)

Опубликована: Янв. 31, 2025

Prostate cancer (PCa) is the most commonly detected malignancy in men worldwide. PCa a slow-growing with absence of symptoms at early stages. The pathogenesis has not been entirely understood including key risk factors related to development like diet and microbiota derived metabolites. Microbiota may influence host's immunological responses, inflammatory metabolic pathways, which be crucial for metastasis. Similarly, short-chain fatty acids, methylamines, hippurate, bile other metabolites generated by have potential roles inflammation progression cancer. Most studies focused on role their pathways involved chronic inflammation, tumor initiation, proliferation, progression. In summary, review discusses microbial-derived metabolite-built strategies PCa.

Язык: Английский

Role of Microbiota‐Derived Metabolites in Prostate Cancer Inflammation and Progression DOI Open Access
Pradeep Kumar Rathinavelu, Anil Kumar, Virendra Kumar

и другие.

Cell Biochemistry and Function, Год журнала: 2025, Номер 43(2)

Опубликована: Янв. 31, 2025

Prostate cancer (PCa) is the most commonly detected malignancy in men worldwide. PCa a slow-growing with absence of symptoms at early stages. The pathogenesis has not been entirely understood including key risk factors related to development like diet and microbiota derived metabolites. Microbiota may influence host's immunological responses, inflammatory metabolic pathways, which be crucial for metastasis. Similarly, short-chain fatty acids, methylamines, hippurate, bile other metabolites generated by have potential roles inflammation progression cancer. Most studies focused on role their pathways involved chronic inflammation, tumor initiation, proliferation, progression. In summary, review discusses microbial-derived metabolite-built strategies PCa.

Язык: Английский

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