Helicoverpa
armigera
poses
a
significant
threat
to
numerous
vital
agricultural
crops
resulting
in
extensive
damage
and
presenting
grave
challenge
the
global
economy.
The
current
study
investigated
growth
regulatory
potential
of
triflumuron
(TFM)
β-sitosterol
(BS)
individually
three
combinations
(1:1,
1:5
1:10)
formulate
an
effective
management
tool
against
H.
armigera.
Rearing
fourth
instar
larvae
on
dietary
TFM
imparted
negative
effects
larval
development
mortality
every
developmental
stage
reduced
adult
emergence;
were
higher
relative
BS.
TFM+BS
also
showed
appreciable
inhibitory
with
IE30,
IE50,
IE90
values
by
0.048,
0.064,
0.019-fold
compared
BS-diet,
0.51,
0.36,
0.15-fold
TFM-diet,
respectively.
Among
diets,
only
1:1
inhibition
emergence
indicating
synergistic
action
BS
when
equal
proportion
TFM.
Dietary
(1:1)
at
sub-lethal
dosage
increased
just
54.37%
weight
until
pupation,
contrast
81.30%
increase
induced
140.83%
216.44%
control
diet
(p
<
0.05).
Further
exerted
moulting
disruptions,
inability
ecdyse
impeded
new
cuticle
formation
leading
decline
survival,
30%
94%
controls,
70%
BS-diet
48%
TFM-diet.
results
demonstrate
that
combining
proportions
can
effectively
amplified
activity
It
is
proposed
that,
this
two-pronged
approach
be
eco-friendly
alternative
synthetic
pesticides
for
This
first
its
kind
which
helpful
if
fields.
Frontiers in Physiology,
Год журнала:
2023,
Номер
14
Опубликована: Ноя. 27, 2023
The
eusocial
pest,
red
imported
fire
ant
(
Solenopsis
invicta
),
is
a
highly
invasive
species
that
poses
significant
threats
to
public
safety,
agriculture,
and
the
ecological
environment.
Cycloxaprid,
newly
identified
effective,
slow-acting,
non-repellent
insecticide
against
S.
,
allows
contaminated
individuals
transfer
among
nestmates
through
body
contact.
However,
molecular-level
changes
occurring
in
post
cycloxaprid
exposure
any
molecular
alterations
contributing
slow
demise
or
decreased
sensitivity
remain
unclear.
In
this
study,
transcriptomic
metabolomic
techniques
were
used
investigate
mechanisms
of
exposed
cycloxaprid.
Differential
analysis
results
revealed
275,
323,
536
differentially
expressed
genes
at
12,
24,
48
h,
respectively.
Genes
involved
lipid
energy
metabolism,
DNA
integration,
hormone
synthesis
largely
upregulated
12
suggesting
might
actively
resist
impacts,
predominantly
downregulated
indicating
further
functional
impairment
impending
death.
Also,
we
observed
an
imbalance
olfactory
perception
pathways
which
may
indicate
disruption
system
.
Metabolomic
showed
regulation
most
differential
metabolites
(DMs)
was
consistent
with
expression
their
related
DEGs
different
time
points.
Our
study
provides
insights
into
mechanism
underlying
slow-acting
properties
