F1000Research,
Год журнала:
2024,
Номер
13, С. 330 - 330
Опубликована: Апрель 23, 2024
Background
&
Purpose
Falls
and
balance
issues
are
significant
concerns
for
the
elderly.
Treadmill
training
is
increasingly
recognized
as
a
potential
intervention
to
improve
reduce
fall
risk
in
this
population.
This
systematic
review
evaluates
effectiveness
of
treadmill
on
Methods
A
comprehensive
search
was
conducted
databases
including
MEDLINE,
EMBASE,
CINAHL
Plus,
PEDro,
Cochrane
Library,
ERIC
from
January
1,
1980,
May
31,
2023.
The
focused
training’s
impact
older
adults.
From
74
identified
studies,
outcome
measures
were
categorized
into
groups
like
“Balance
Improvement,”
“Gait
“Mobility
Enhancement,”
“Muscle
Strength
“Cognitive
Function
Quality
Life,”
others.
Articles
excluded
reasons
irrelevance
training,
language
barriers,
or
duplication,
resulting
16
final
studies.
Results
shows
diverse
positive
effects
Perturbation-based
reduces
falls,
walking
enhances
quality
life,
particularly
institutionalized
individuals.
Benefits
noted
Parkinson’s
patients’
gait,
cognitive
changes
neurophysiology,
fitness
mobility
improvements
through
underwater
sessions,
refined
gait
hemiparetic
patients.
Conclusion
interventions
promising
improving
elderly,
those
with
disease,
spinal
cord
injuries,
age-related
issues.
While
these
show
potential,
further
research
needed
determine
optimal
protocols,
durations,
combinations
other
interventions.
could
lead
more
approach
addressing
challenges
promoting
healthy
aging
reducing
risks.
Antioxidants,
Год журнала:
2024,
Номер
13(5), С. 573 - 573
Опубликована: Май 7, 2024
This
review
comprehensively
evaluates
the
effects
of
physical
exercise
on
oxidative
and
nitrosative
stress,
mainly
focusing
role
antioxidants.
Using
a
narrative
synthesis
approach,
data
from
empirical
studies,
reviews,
systematic
meta-analyses
published
between
2004
2024
were
collated
databases
like
PubMed,
EBSCO
(EDS),
Google
Scholar,
culminating
in
inclusion
41
studies.
The
quality
these
studies
was
rigorously
assessed
to
ensure
clarity
objectives,
coherence
arguments,
comprehensive
literature
coverage,
depth
critical
analysis.
Findings
revealed
that
moderate
enhances
antioxidant
defenses
through
hormesis,
while
excessive
may
exacerbate
stress.
also
highlights
natural
dietary
antioxidants
are
beneficial,
high-dose
supplements
could
impede
positive
adaptations
exercise.
In
conclusion,
calls
for
more
focused
research
tailored
nutrition
plans
further
understand
complex
interactions
optimize
health
outcomes
athletes
general
population.
Acta Physiologica,
Год журнала:
2024,
Номер
240(3)
Опубликована: Фев. 2, 2024
Abstract
Sarcopenia
lowers
the
quality‐of‐life
for
millions
of
people
across
world,
as
accelerated
loss
skeletal
muscle
mass
and
function
contributes
to
both
age‐
disease‐related
frailty.
Physical
activity
remains
only
proven
therapy
sarcopenia
date,
but
alternatives
are
much
sought
after
manage
this
progressive
disorder
in
individuals
who
unable
exercise.
Mitochondria
have
been
widely
implicated
etiology
increasingly
suggested
attractive
therapeutic
targets
help
restore
perturbed
balance
between
protein
synthesis
breakdown
that
underpins
atrophy.
Reviewing
current
literature,
we
note
mitochondrial
bioenergetic
changes
generally
interpreted
intrinsic
dysfunction
renders
cells
incapable
making
sufficient
ATP
fuel
synthesis.
Based
on
reported
effects
interventions,
however,
argue
observed
may
instead
reflect
an
adaptation
pathologically
decreased
energy
expenditure
sarcopenic
muscle.
Discrimination
these
mechanistic
possibilities
will
be
crucial
improving
management
sarcopenia.
Frontiers in Physiology,
Год журнала:
2025,
Номер
16
Опубликована: Март 26, 2025
Skeletal
muscle
atrophy,
characterized
by
the
loss
of
mass
and
function,
can
result
from
disuse,
aging,
disease,
drug.
Exercise
preconditioning—a
form
exercise
training
performed
before
these
harmful
threats—induces
notable
remodeling
extensive
biochemical
adaptations
in
skeletal
muscle,
creating
a
protective
phenotype
fibers,
thus
serving
as
an
effective
intervention
for
preventing
atrophy.
Here,
we
review
current
understanding
relating
to
how
preconditioning
protects
damage
caused
inactivity,
sarcopenia,
or
pharmacological
intervention,
with
emphasis
on
cellular
mechanisms
involved.
Key
highlighted
making
significant
contribution
effects
fibers
include
mitochondria;
expression
cytoprotective
proteins
such
HSP72,
SOD2,
SESN2,
PGC-1α
AMPK;
regulation
oxidative
stress.
These
findings
underscore
potential
non-pharmacological
preserving
well
muscular
ultimately
improving
quality
life
at-risk
populations.
Frontiers in Nutrition,
Год журнала:
2024,
Номер
11
Опубликована: Апрель 5, 2024
Background
Oxidative
Balance
Score
(OBS)
is
a
tool
for
assessing
the
oxidative
stress-related
exposures
of
diet
and
lifestyle.
The
study
aimed
to
investigate
association
between
OBS
low
muscle
mass.
Methods
Overall,
6,307
individuals
over
age
18
were
assessed
using
data
from
2011
2018
National
Health
Nutrition
Examination
Survey
(NHANES).
Weighted
logistic
regression
models
used,
together
with
adjusted
models.
Results
There
was
negative
relationship
mass
[odds
ratio
(OR):
0.96,
95%
confidence
interval
(CI):
0.94–0.97,
p
<
0.0001]
first
level
as
reference.
values
(all
CI)
0.745
(0.527–1.054)
second
level,
0.650
(0.456–0.927)
third
0.326
(0.206–0.514)
fourth
(P
trend
<0.0001).
Independent
links
found
lifestyle
factors.
A
restricted
cubic
spline
model
indicated
non-linear
risk
non-linearity<0.05).
In
addition,
inflection
points
nonlinear
curves
20.
Conclusion
be
significantly
negatively
correlated.
By
modulating
balance,
healthy
antioxidant
rich
could
preventive
strategy
Life,
Год журнала:
2024,
Номер
14(8), С. 962 - 962
Опубликована: Июль 31, 2024
Sarcopenia,
the
age-related
decline
in
muscle
mass
and
function,
poses
a
significant
health
challenge
as
global
population
ages.
Mitochondrial
dysfunction
is
key
factor
sarcopenia,
evidenced
by
role
of
mitochondrial
reactive
oxygen
species
(mtROS)
biogenesis
dynamics,
well
mitophagy.
Resistance
exercise
training
(RET)
well-established
intervention
for
sarcopenia;
however,
its
effects
on
mitochondria
aging
skeletal
muscles
remain
unclear.
This
review
aims
to
elucidate
relationship
between
dynamics
with
specific
focus
implications
RET.
Although
aerobic
(AET)
has
traditionally
been
viewed
more
effective
enhancement,
emerging
evidence
suggests
that
RET
may
also
confer
beneficial
effects.
Here,
we
highlight
potential
modulate
mtROS,
drive
biogenesis,
optimize
promote
mitophagy
muscles.
Understanding
this
interplay
offers
insights
combating
sarcopenia
preserving
individuals.
International Journal of General Medicine,
Год журнала:
2024,
Номер
Volume 17, С. 1861 - 1876
Опубликована: Май 1, 2024
Objective:
This
bibliometric
analysis
and
review
aimed
to
examine
the
current
research
status
trends
in
combination
of
nutrition
exercise
training
for
sarcopenia.
Additionally,
it
sought
provide
researchers
with
future
directions
this
field.
Methods:
Relevant
publications
were
obtained
from
Web
Science
Core
Collection
(WoSCC)
database,
covering
period
January
1995
October
2023.
The
collected
analyzed
using
CiteSpace,
VOSviewer,
Bibliometrix,
Review
Manager.
Results:
Out
2528
retrieved
publications,
United
States
emerged
as
leading
contributor
terms
publication
volume.
University
Texas
System
was
identified
most
productive
institution.
Luc
J
C
van
Loon
published
author
Analysis
keywords
revealed
recent
hot
topics
emerging
areas
interest,
such
"gut
microbiota"
"mechanisms".
Upon
further
evaluation,
resistance
(RT)
protein
supplementation
commonly
employed
effective
methods.
Conclusion:
RT
are
widely
recognized
strategies.
Future
should
focus
on
investigating
molecular
aspects
Moreover,
potential
therapeutic
role
gut
microbiota
sarcopenia
requires
comprehensive
investigation
human
subjects
establish
its
correlation.
Keywords:
sarcopenia,
nutrition,
exercise,
analysis,
F1000Research,
Год журнала:
2025,
Номер
13, С. 330 - 330
Опубликована: Фев. 10, 2025
Background
&
Purpose
Falls
and
balance
issues
are
significant
concerns
for
the
elderly.
Treadmill
training
is
increasingly
recognized
as
a
potential
intervention
to
improve
reduce
fall
risk
in
this
population.
This
systematic
review
evaluates
effectiveness
of
treadmill
on
Methods
A
comprehensive
search
was
conducted
databases
including
MEDLINE,
EMBASE,
CINAHL
Plus,
PEDro,
Cochrane
Library,
ERIC
from
January
1,
1980,
2025.
The
focused
training’s
impact
older
adults.
From
74
identified
studies,
primary
outcome
measure
“Balance
Improvement,
fall”
secondary
were
“Cognitive
Function
Quality
Life,”
others.
Articles
excluded
reasons
like
irrelevance
training,
language
barriers,
or
duplication,
resulting
16
final
studies.
Results
demonstrated
positive
effects
reduction,
particularly
elderly
individuals
with
Parkinson’s
disease,
spinal
cord
injuries,
age-related
issues.
Perturbation-based
significantly
reduced
rates,
while
underwater
sessions
improved
mobility
cognitive
function.
Conclusion
interventions
promising
improving
elderly,
those
While
these
show
potential,
further
research
needed
determine
optimal
protocols,
durations,
combinations
other
interventions.
could
lead
more
approach
addressing
challenges
promoting
healthy
aging
reducing
risks.
