Bioinformatics Analysis of the Glutamate-Gated Chloride Channel Family in Bursaphelenchus xylophilus

International Journal of Molecular Sciences, Год журнала: 2025, Номер 26(8), С. 3477 - 3477

Опубликована: Апрель 8, 2025

Glutamate-gated chloride channels (GluCls), a class of ion found in the nerve and muscle cells invertebrates, are involved vital life processes. Bursaphelenchus xylophilus, pathogen pine wilt disease, has induced major economic ecological losses invaded areas Asia Europe. We identified 33 GluCls family members by sequence alignment analysis. A subsequent bioinformatic analysis revealed physicochemical properties, protein structure, gene expression patterns different developmental stages. The results showed that genes distributed across all six chromosomes B. xylophilus. These proteins indicated relatively conserved structure NCBI-conserved domains InterPro consist 5 to 14 exons. Expression pattern BxGluCls were extensively development second instar larvae Furthermore, BxGluCls15, BxGluCls25, BxGluCls28 mainly associated with eggs BxGluCls12, BxGluCls18, BxGluCls32 predominantly linked nematode resistance adaptation. Investigation is crucial understand trends It also helps identify molecular targets for biopesticides or drugs designed control this nematode.

Язык: Английский

Immunity in Molluscs

Elsevier eBooks, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

Язык: Английский