Physical activity and exercise health benefits: cancer prevention, interception, and survival
European Journal of Cancer Prevention,
Год журнала:
2024,
Номер
34(1), С. 24 - 39
Опубликована: Май 29, 2024
Physical
activity
(PA)
has
an
established
role
in
the
promotion
of
health
and
fitness
prevention
disease.
Expected
overall
benefits
include
reduction
all-cause
morbidity
death,
weight
control,
improved
quality
life,
bone
decreased
falls
elderly
subjects,
,
deeper
cognition,
reduced
risk
depression,
anxiety,
sleeplessness.
Currently,
PA
is
a
mainstay
management
cardiovascular
diseases,
metabolic
syndrome,
diabetes,
health.
Recently,
perception
its
primary
secondary
prevention,
interception,
treatment
cancer,
however,
also
gaining
importance.
Regular
walking,
simplest
type
PA,
associated
with
disease
mortality,
cancer
increasing
interest.
Furthermore,
improves
life
patients,
attenuating
side
effects
chemotherapy,
decreasing
sarcopenia,
fitness,
inhibiting
recurrence
progression
some
types.
It
promotes
emotional
psychological
inducing
positive
changes.
While
mechanisms,
effective
levels
useful
amount
practice
are
well
cardiology,
they
yet
to
be
fully
determined
oncology.
Nevertheless,
recommended
reduce
general
population,
it
been
introduced
programs
for
second
cancers.
In
perspective,
will
help
as
integrative
therapy
patients
survivors.
The
number
beneficial
continuum
highlighted
this
review.
Язык: Английский
Macrophages and T cells in metabolic disorder-associated cancers
Nature reviews. Cancer,
Год журнала:
2024,
Номер
unknown
Опубликована: Окт. 1, 2024
Язык: Английский
Humanistic Health Management and Cancer: Associations of Psychology, Nutrition, and Exercise with Cancer Progression and Pathogenesis
Advanced Science,
Год журнала:
2024,
Номер
11(22)
Опубликована: Март 25, 2024
Abstract
The
incidence
rate
of
cancer
is
increasing
year
by
due
to
the
aging
population,
unhealthy
living,
and
eating
habits.
At
present,
surgery
medication
are
still
main
treatments
for
cancer,
without
paying
attention
impact
individual
differences
in
health
management
on
cancer.
However,
evidence
suggests
that
psychological
status,
dietary
habits,
exercise
frequency
closely
related
risk
prognosis
reminder
humanity
medical
concept
unified
treatment
plan
insufficient
treatment,
a
personalized
may
become
breakthrough
point.
On
this
basis,
“Humanistic
Health
Management”
(HHM)
proposed.
This
healthcare
focuses
self‐health
management,
providing
an
accurate
comprehensive
evaluation
lifestyle
psychology,
developing
targeted
prevention
plans.
review
will
provide
detailed
explanation
relationship
between
dietary,
regulatory
mechanisms
Intended
emphasize
importance
HHM
better
prognostic
efficacy,
new
ideas
generation
treatment.
Язык: Английский
Perioperative Immunosuppressive Factors during Cancer Surgery: An Updated Review
Cancers,
Год журнала:
2024,
Номер
16(13), С. 2304 - 2304
Опубликована: Июнь 22, 2024
Surgical
excision
of
the
primary
tumor
represents
most
frequent
and
curative
procedure
for
solid
malignancies.
Compelling
evidence
suggests
that,
despite
its
beneficial
effects,
surgery
may
impair
immunosurveillance
by
triggering
an
immunosuppressive
inflammatory
stress
response
favor
recurrence
stimulating
minimal
residual
disease.
In
addition,
many
factors
interfere
with
immune
effectors
before
after
cancer
procedures,
such
as
malnutrition,
anemia,
or
subsequent
transfusion.
Thus,
perioperative
period
plays
a
key
role
in
determining
oncological
outcomes
short
phase
to
circumvent
anesthetic
surgical
deleterious
supporting
system
through
use
synergistic
pharmacological
non-pharmacological
approaches.
line
this,
accumulating
studies
indicate
that
agents
could
drive
both
protumor
antitumor
signaling
pathways
during
surgery.
While
preclinical
investigations
focusing
on
anesthetics'
impact
behavior
cells
are
quite
convincing,
limited
clinical
trials
studying
consequences
survival
recurrences
remain
inconclusive.
Herein,
we
highlight
main
occurring
their
potential
immunomodulation
progression.
We
also
discuss
patient
management
prior
surgery,
taking
into
consideration
latest
advances
literature.
Язык: Английский
Effect of subcutaneous fat on long-term survival after surgery for stage I-III breast cancer as determined by computed tomography
Frontiers in Oncology,
Год журнала:
2025,
Номер
15
Опубликована: Март 17, 2025
Monitoring
body
composition
through
Computed
Tomography
(CT)
scans,
including
muscle
and
adipose
tissue,
plays
a
key
role
in
the
prognosis
of
various
cancers.
However,
abdominal
CT
is
impractical
for
patients
with
breast
cancer
(BC),
making
chest
an
essential
tool
postoperative
surveillance.
This
study
aims
to
evaluate
effect
subcutaneous
fat
tissue
at
11th
thoracic
vertebral
plane
on
BC
by
analyzing
images,
providing
evidence
nutritional
rehabilitation
guidance.
We
conducted
retrospective
analysis
medical
records
188
treated
discharged
from
Second
Affiliated
Hospital
Wenzhou
Medical
University
between
January
1,
2013,
December
31,
2013.
The
area
(SFA)
vertebra
(T11)
was
measured
using
index
(SFI,
area/height2)
calculated.
Using
multivariate
Cox
proportional
hazards
models
propensity
score
matching
(PSM),
relationships
SFI
overall
survival
(OS),
as
well
recurrence-free
(RFS),
were
assessed.
Additionally,
Kaplan-Meier
curves
applied
compare
prognostic
differences
groups.
median
follow-up
duration
128
months
(range:
27-188
months).
Of
included
study,
optimal
cutoff
value
determined
be
49.31
cm²/m².
Multivariate
indicated
that
independent
factor
both
OS
(HR
2.50,
95%
CI
1.07-5.83,
P
=
0.034)
RFS
2.04,
1.10-3.78,
0.024).
After
PSM,
curve
revealed
significant
two
groups
(P
0.025
0.018,
respectively).
All
results
showed
more
poor.
findings
demonstrated
T11
negatively
correlated
patient
survival.
offers
new
perspective
personalized
management
patients,
suggesting
future
research
should
validate
these
investigate
combining
imaging
assessments
lifestyle
interventions,
such
exercise,
nutrition,
diet,
optimize
outcomes.
Язык: Английский
Role and mechanisms of exercise therapy in enhancing drug treatment for glioma: a review
Frontiers in Immunology,
Год журнала:
2025,
Номер
16
Опубликована: Апрель 30, 2025
Gliomas,
particularly
glioblastoma
(GBM),
are
among
the
most
aggressive
and
challenging
brain
tumors
to
treat.
Although
current
therapies
such
as
chemotherapy,
radiotherapy,
targeted
treatments
have
extended
patient
survival
some
extent,
their
efficacy
remains
limited
is
often
accompanied
by
severe
side
effects.
In
recent
years,
exercise
therapy
has
gained
increasing
attention
an
adjunctive
treatment
in
clinical
research
settings.
Exercise
not
only
improves
patients’
physical
function
cognitive
abilities
but
may
also
enhance
of
conventional
drug
modulating
immune
system,
suppressing
inflammatory
responses,
improving
blood-brain
barrier
permeability.
This
review
summarizes
potential
mechanisms
glioma
treatment,
including
enhancing
surveillance
through
activation
natural
killer
(NK)
cells
T
cells,
penetration
function.
Additionally,
studies
suggest
that
can
synergize
with
chemotherapy
immunotherapy,
outcomes
while
reducing
drug-related
application
patients
still
exploratory
phase,
existing
evidence
indicates
its
significant
value
approach,
become
a
new
standard
future.
Язык: Английский
Mechanistic Insight into Physical Activity Pleiotropy in Cancer Prevention
Exercise Sport and Movement,
Год журнала:
2024,
Номер
2(4)
Опубликована: Сен. 23, 2024
ABSTRACT
Although
improvements
in
prevention
and
screening
have
curbed
the
incidence
of
some
cancers,
global
burden
cancer
is
substantial
continues
to
grow.
The
sustained
high
prevalence
many
cancers
reveals
need
for
additional
strategies
reduce
occurrence.
Observational
studies
linked
physical
inactivity
risk
13
different
cancers.
Indeed,
activity
can
occurrence
several
by
more
than
20%,
whereas
sedentary
behavior
increase
risk.
Thus,
presents
a
viable
lifestyle
intervention
cancer,
current
research
efforts
are
focused
on
establishing
effective
mode
intensity
prevention.
Preclinical
provided
insight
into
mechanisms
mediating
these
effects.
There
growing
evidence
that
1)
obesity
and,
extension,
metabolic
dysregulation;
2)
improve
immune
surveillance
inflammation;
3)
enrich
colonic
environment
favoring
beneficial
microbes
reducing
transit
time;
4)
regulate
sex
hormones.
This
graphical
review
describes
state
knowledge
benefits
associated
plausible
mechanisms.
Язык: Английский