Sample Preparation for Metabolomic Analysis in Exercise Physiology DOI Creative Commons
Valeriya I. Nakhod, Tatiana V. Butkova, Kristina A. Malsagova

и другие.

Biomolecules, Год журнала: 2024, Номер 14(12), С. 1561 - 1561

Опубликована: Дек. 7, 2024

Metabolomics investigates final and intermediate metabolic products in cells. Assessment of the human metabolome relies principally on analysis blood, urine, saliva, sweat, feces. Tissue biopsy is employed less frequently. Understanding metabolite composition biosamples from athletes can significantly improve our knowledge molecular processes associated with efficiency training recovery. Such may also lead to new management opportunities. Successful execution metabolomic studies requires simultaneous qualitative quantitative analyses numerous small biomolecules samples under test. Unlike genomics proteomics, which do not allow for direct assessment enzymatic activity, metabolomics focuses biochemical phenotypes, providing unique information about health physiological features. Crucial factors ensuring efficacy are meticulous selection pre-treatment samples.

Язык: Английский

Combined Mediterranean Diet-based Sustainable Healthy Diet and Multicomponent Training intervention impact on plasma biomarkers and metabolome in older adults DOI Creative Commons
Joana Sampaio, Joana Pinto, Andréia Pizarro

и другие.

Clinical Nutrition, Год журнала: 2024, Номер 43(9), С. 2125 - 2135

Опубликована: Июль 26, 2024

Healthy dietary patterns and exercise practices have been associated with improved metabolic inflammatory profiles. However, studies regarding the combined effect of these interventions on plasma biomarkers metabolome in older adults are sparser. The primary aim this study was to investigate impact a Mediterranean Diet-based Sustainable Diet (SHD) Multicomponent Training (MT) intervention how intake could modulate effects.

Язык: Английский

Процитировано

3

Sports Genomics and the Intersection of Genetics and Training in Sports DOI

Sapna Vyas,

Ravi Teja Mandapaka

Advances in medical diagnosis, treatment, and care (AMDTC) book series, Год журнала: 2024, Номер unknown, С. 355 - 380

Опубликована: Окт. 14, 2024

Nutrigenomics and nutrigenetics combine nutrition, genetics, sports science to personalize nutrition. These fields study how an individual's genetic makeup interacts with specific foods optimize athletic performance overall well-being. Genetic variations in energy metabolism, muscle growth, recovery inform personalized nutrition plans. Through testing, markers linked nutrient metabolism attributes create comprehensive nutritional profiles for customized dietary approaches. As authors of this manuscript, we are confident that research contributes the growing body literature genomics, providing insights into basis paving way approaches training optimization. The future lies its ability adapt unique each athlete, a tailored roadmap achieving their highest potential.

Язык: Английский

Процитировано

1

The Effect of Exercise Intensity on Pancreatic and Liver GLUT-2 Expression in High Fructose-Fed Mice DOI Creative Commons

Tantia Dewi Harianto,

Bagas Trio Pamungkas,

Purwo Sri Rejeki

и другие.

Retos, Год журнала: 2024, Номер 57, С. 35 - 47

Опубликована: Июль 5, 2024

Excessive high fructose corn syrup (HFCS) leads to metabolic disorders characterized by decreased expression of pancreatic GLUT-2 and increased liver GLUT-2. Exercise is reported be a non-pharmacological therapy improve disorders. This study aims compare differences in exercise intensity changes mice induced fructose. A total 36 male (Mus musculus), weighing 20-30 grams, 8-week-old, were randomly divided into 4 groups: C (Control; n = 9), G1 (light swimming exercises; G2 (moderate G3 (heavy 9). All groups given 30% solution orally (oral ad libitum) for 8 weeks. Meanwhile, was out 3×/week weeks with three different intensities. Pancreatic measured using immunohistochemistry (IHC) the results measurements evaluated Immunoreactive Score (IRS). The analysis body weight one-way ANOVA followed Tukey's Honest Significant Difference (HSD) post hoc test indicates that significantly reduces compared C, G1, (p ≤ 0.05). Statistical done Kruskal-Wallis non-parametric up Mann-Whitney U Test significant level 5%. data showed In conclusion, moderate-intensity has most optimal effect increasing decreasing Keywords: Obesity, Insulin resistance, expression, Exercise, High

Язык: Английский

Процитировано

0

Food metabolomics for improvement of nutrition and well-being DOI Creative Commons
Enik Nurlaili Afifah, Sastia Prama Putri

BIO Web of Conferences, Год журнала: 2024, Номер 127, С. 07001 - 07001

Опубликована: Янв. 1, 2024

Food metabolomics is an emerging field that employs comprehensive analytical techniques, such as Gas Chromatography-Mass Spectrometry (GC-MS), Liquid (LC-MS), and Nuclear Magnetic Resonance (NMR), to identify quantify essential nutrients bioactive compounds in foods, link their impact on human health. By integrating metabolomic data with nutritional science, researchers can better elucidate how dietary components influence metabolic processes contribute overall health well-being. This review highlights recent studies food metabolomics, providing a detailed understanding of its application assessing value, optimizing recommendations, improving quality. The role precision nutrition well-being significant, advancements this research area are discussed.

Язык: Английский

Процитировано

0

Sample Preparation for Metabolomic Analysis in Exercise Physiology DOI Creative Commons
Valeriya I. Nakhod, Tatiana V. Butkova, Kristina A. Malsagova

и другие.

Biomolecules, Год журнала: 2024, Номер 14(12), С. 1561 - 1561

Опубликована: Дек. 7, 2024

Metabolomics investigates final and intermediate metabolic products in cells. Assessment of the human metabolome relies principally on analysis blood, urine, saliva, sweat, feces. Tissue biopsy is employed less frequently. Understanding metabolite composition biosamples from athletes can significantly improve our knowledge molecular processes associated with efficiency training recovery. Such may also lead to new management opportunities. Successful execution metabolomic studies requires simultaneous qualitative quantitative analyses numerous small biomolecules samples under test. Unlike genomics proteomics, which do not allow for direct assessment enzymatic activity, metabolomics focuses biochemical phenotypes, providing unique information about health physiological features. Crucial factors ensuring efficacy are meticulous selection pre-treatment samples.

Язык: Английский

Процитировано

0