Improving brain health via the central executive network
The Journal of Physiology,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 24, 2025
Abstract
Cognitive
and
physical
stress
have
significant
effects
on
brain
health,
particularly
through
their
influence
the
central
executive
network
(CEN).
The
CEN,
which
includes
regions
such
as
dorsolateral
prefrontal
cortex,
anterior
cingulate
cortex
inferior
parietal
lobe,
is
to
managing
demands
of
cognitively
challenging
motor
tasks.
Acute
can
temporarily
reduce
connectivity
within
leading
impaired
cognitive
function
emotional
states.
However
a
rebound
in
these
states
often
follows,
driven
by
motivational
signals
mesocortical
mesolimbic
pathways,
help
sustain
inhibitory
control
task
execution.
Chronic
exposure
challenges
leads
long‐term
improvements
CEN
functionality.
These
changes
are
supported
neurochemical,
structural
systemic
adaptations,
including
mechanisms
tissue
crosstalk.
Myokines,
adipokines,
anti‐inflammatory
cytokines
gut‐derived
metabolites
contribute
biochemical
environment
that
enhances
neuroplasticity,
reduces
neuroinflammation
supports
neurotransmitters
serotonin
dopamine.
processes
strengthen
connectivity,
improve
self‐regulation
enable
individuals
adopt
health‐optimizing
behaviours.
Long‐term
activity
not
only
but
also
risk
age‐related
decline
neurodegenerative
diseases.
This
review
highlights
role
progressive
exercise
practical
approach
strengthening
promoting
offering
strategy
resilience
well‐being
across
lifespan.
image
Язык: Английский
Physical activity, cathepsin B, and cognitive health
Trends in Molecular Medicine,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
Язык: Английский
Exploring the causal relationship between delirium and sarcopenia using bidirectional two-sample Mendelian randomization study
Progress in Neuro-Psychopharmacology and Biological Psychiatry,
Год журнала:
2025,
Номер
unknown, С. 111327 - 111327
Опубликована: Март 1, 2025
Язык: Английский
Acute effects of resistance exercise intensity and repetition at a predetermined volume on inhibitory control: a randomized controlled trial
Frontiers in Sports and Active Living,
Год журнала:
2025,
Номер
7
Опубликована: Март 13, 2025
Background
This
study
explores
the
effects
of
acute
resistance
exercise
(RE)
on
inhibitory
control
(IC),
emphasizing
volume.
Methods
In
total,
78
young
adults
were
randomly
assigned
to
one
three
groups:
moderate-intensity
group
[MI;
60%
repetition
maximum
(1RM),
3
×
10
reps],
low-intensity
(LI;
30%
1RM,
20
reps),
or
(CON;
35
min
reading).
The
groups
volume-matched.
Baseline
equivalence
was
assessed
via
one-way
analysis
variance
(ANOVA)
for
demographic
variables
and
chi-square
gender.
One-way
covariance
examined
post-test
interreference
inverse
efficiency
score
scores,
controlling
pre-test
values.
Two-way
ANOVA
Group
(MI,
LI,
CON)
Time
heart
rate
(resting;
pre-test,
during
intervention,
post-test),
perceived
exertion
(pre-test,
lactate
mid-test,
post-test).
Mean
differences
95%
confidence
intervals
supplemented
p
-values.
Results
IC
using
Stroop
Task,
revealing
better
performance
in
both
MI
(
=
0.026)
LI
0.040)
compared
CON,
though
no
significant
difference
found
between
two
groups.
Blood
levels
significantly
increased
post-exercise
0.012)
<
0.001)
groups,
but
again,
there
them.
Conclusions
These
findings
highlight
that
RE,
regardless
intensity,
enhances
raises
blood
when
volume
is
controlled.
Practitioners
might
tailor
RE
protocols
by
adjusting
intensity
match
individuals’
capabilities
without
compromising
cognitive
physiological
benefits.
Clinical
Trial
Registration
identifier
(NCT05311202).
Язык: Английский