Antimicrobial efficacy of Mentha piperata-derived biogenic zinc oxide nanoparticles against UTI-resistant pathogens

Scientific Reports, Год журнала: 2023, Номер 13(1)

Опубликована: Сен. 11, 2023

Abstract Misuse of antibiotics leads to the worldwide spread antibiotic resistance, which motivates scientists create new antibiotics. The recurring UTI due antibiotics-resistant microorganism’s challenges globally. biogenic nanoparticles have potential meet escalating requirements novel antimicrobial agents. green synthesis (NPs) gained more attention their reliable applications against resistant microbes. current study evaluates ZnO NPs Mentha piperata extract pathogens urinary tract infections by agar well diffusion assay. revealed comparatively maximum inhibition in comparison synthetic two bacterial strains ( Proteus mirabilis , Pseudomonas aeruginosa ) and a fungal strain Candida albicans ).The synthesized alone activities than combination plant (PE) NPs, PE alone. physiochemical features characterized through UV–Vis spectroscopy, FTIR, XRD, SEM, EDX. spectroscopy 281.85 nm wavelengths; XRD pattern crystalline structure NPs. FTIR analysis presence carboxylic nitro groups, could be attributed extract. SEM spherical hollow symmetry electrostatic forces. via EDX confirmed Zn oxygen sample. provide pivotal information such as quality effectiveness. excellent dose-dependent activity pathogenic isolates from UTI-resistant patients. higher concentration ZnONPs interacts with cell membrane triggers oxidative burst. They may bind enzymes proteins brings epigenetic alteration disruption or death.

Язык: Английский

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Recent Trends in Biologically Synthesized Metal Nanoparticles and their Biomedical Applications: a Review

Biological Trace Element Research, Год журнала: 2023, Номер 202(7), С. 3383 - 3399

Опубликована: Окт. 25, 2023

Язык: Английский

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A narrative review of the synthesis, characterization, and applications of iron oxide nanoparticles

Discover Nano, Год журнала: 2023, Номер 18(1)

Опубликована: Окт. 10, 2023

Abstract The significance of green synthesized nanomaterials with a uniform shape, reduced sizes, superior mechanical capabilities, phase microstructure, magnetic behavior, and performance cannot be overemphasized. Iron oxide nanoparticles (IONPs) are found within the size range 1–100 nm in have diverse applications fields such as biomedicine, wastewater purification, environmental remediation. Nevertheless, understanding their fundamental material composition, chemical reactions, toxicological properties, research methodologies is constrained extensively elucidated during practical implementation. importance producing IONPs using advanced nanofabrication techniques that exhibit strong potential for disease therapy, microbial pathogen control, elimination cancer cells underscored by adoption synthesis approach. These can serve viable alternatives soil remediation contaminants. Therefore, this paper presents comprehensive analysis conducted on different types IONP composite-based materials. It examines methods characterization employed these studies also addresses obstacles encountered prior investigations comparable objectives. A engineering strategy was proposed synthesis, characterization, application composites impact. Additionally, influence structure, biocompatibility, toxicity, milling time, nanoparticle size, shape discussed. study proposes use biological physicochemical more alternative mitigate limitations imposed conventional synthesis.

Язык: Английский

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Magnetic iron oxide-based nanozymes: from synthesis to application

Nanoscale Advances, Год журнала: 2024, Номер 6(6), С. 1611 - 1642

Опубликована: Янв. 1, 2024

Iron oxide nanozymes (IONzymes) are a class of magnetic nanoparticles that mimic the enzymatic activity natural enzymes. These particles have received significant attention in recent years due to their unique properties, such as high stability, tunable responsiveness, and ability act biocatalysts for various chemical reactions. In this review, we aim provide an overview production methods nanozymes, including chemical, physical, biological synthesis. The structure design also discussed detail, well applications fields biomedicine environmental science. results studies latest advances field discussed. This review provides valuable insights into current state highlights potential further development application fields.

Язык: Английский

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Biogenic synthesis, characterization, and in vitro biological investigation of silver oxide nanoparticles (AgONPs) using Rhynchosia capitata

Scientific Reports, Год журнала: 2024, Номер 14(1)

Опубликована: Май 7, 2024

Abstract The current research aimed to study the green synthesis of silver oxide nanoparticles (AgONPs) using Rhynchosia capitata (RC) aqueous extract as a potent reducing and stabilizing agent. obtained RC-AgONPs were characterized UV, FT-IR, XRD, DLS, SEM, EDX investigate morphology, size, elemental composition. size was found be ~ 21.66 nm an almost uniform distribution executed by XRD analysis. In vitro studies performed reveal biological potential. AgONPs exhibited efficient DPPH free radical scavenging potential (71.3%), power (63.8 ± 1.77%), total antioxidant capacity (88.5 4.8%) estimate their antioxidative power. Antibacterial antifungal potentials evaluated disc diffusion method against various bacterial fungal strains, zones inhibition (ZOI) determined. A brine shrimp cytotoxicity assay conducted measure (LC 50 : 2.26 μg/mL). addition, biocompatibility tests evaluate biocompatible nature red blood cells, HEK, VERO cell lines (< 200 An alpha-amylase carried out with 67.6% inhibition. Moreover, vitro, anticancer activity Hep-2 liver cancer lines, LC value 45.94 μg/mL achieved. Overall, present has demonstrated that utilization R. for biosynthesis offers cost-effective, eco-friendly, forthright alternative traditional approaches nanoparticle synthesis. significant bioactive properties, positioning them promising candidates diverse applications in spheres medicine beyond.

Язык: Английский

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Bio‐Inspired Synthesis and Photocatalytic Applications of α‐Fe₂O₃@ZnO Nanobinary Using Laurus nobilis Leaf Extract: Efficient for Anionic and Cationic Dye Degradation With Reusability Studies

Applied Organometallic Chemistry, Год журнала: 2025, Номер 39(4)

Опубликована: Март 11, 2025

ABSTRACT This study investigates the sustainable synthesis and applications of α‐Fe₂O₃@ZnO nanocomposites derived using Laurus nobilis leaf extract as a natural reducing agent, promoting eco‐friendly material development for environmental remediation. XRD analysis confirmed formation nanocomposite with crystallite size 21.48 nm, while SEM revealed porous structure uniformly distributed particles ranging from 20 to 50 nm. FTIR spectroscopy identified characteristic Fe‐O Zn‐O bonds, ensuring nanocomposite's purity. Optical showed direct indirect bandgap energies 2.80 1.16 eV, respectively, highlighting its excellent optical properties. The demonstrated remarkable photocatalytic efficiency, achieving 96.3% degradation Brilliant Cresyl Blue (BCB) dye 95.88% Rose Bengal (RB) within 120 min under sunlight irradiation. followed first‐order kinetics, rate constants 0.0241 −1 BCB 0.01875 RB. exhibited reusability, maintaining 93.5% efficiency after five cycles, structural stability throughout repeated use. These results underscore multifunctional potential green‐synthesized dye‐contaminated wastewater treatment, contributing technologies.

Язык: Английский

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Surface Modifications of Superparamagnetic Iron Oxide Nanoparticles with Polyvinyl Alcohol, Chitosan, and Graphene Oxide as Methylene Blue Adsorbents

Coatings, Год журнала: 2023, Номер 13(8), С. 1333 - 1333

Опубликована: Июль 28, 2023

Synthetic dye contamination of wastewater has long been a social issue, with adsorption being the most focused upon research technique among treatment. Using co-precipitation method, superparamagnetic iron oxide nanoparticles (SPIONs) size 13.6 ± 1.9 nm were synthesized. By adsorbing methylene blue (MB) on modified surface SPIONs using polyvinyl alcohol, chitosan, and graphene oxide, entrapment efficiency at pH 7 can be up to 87.00 0.16% after 13 days, highest MB loading capacity was 3.638 0.009%, while amount achieved 36.385 0.095 mg/g. The cumulative desorption adsorbent 3.8 its maximum 8.94 0.66% 30 days. results experiments indicated that compound favorable impact synthetic dyes; nevertheless, more is needed determine ideal ratio, temperature, levels for this chemical.

Язык: Английский

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Biosynthesized silver nanoparticles using Polygonatum geminiflorum efficiently control fusarium wilt disease of tomato

Frontiers in Bioengineering and Biotechnology, Год журнала: 2022, Номер 10

Опубликована: Сен. 8, 2022

Nanomaterials are gaining tremendous potential as emerging antimicrobials in the quest to find resistance-free alternatives of chemical pesticides. In this study, stable silver nanoparticles were synthesized using aqueous extract medicinal plant species Polygonatum geminiflorum , and their morphological features evaluated by transmission electron microscopy, X-ray diffraction spectroscopy energy dispersive analysis. vitro Antifungal activity (AgNPs) P. (PE) either alone or combination (PE-AgNPs) against Fusarium oxysporum was disc-diffusion well-diffusion methods. planta assay same treatments wilt diseases tomato foliar spray method. Moreover, for quantitative investigation antioxidant activity, phenolics flavonoids spectroscopic HPLC techniques. Phytochemical analysis indicated presence total phenolic flavonoid contents 48.32 mg ± 1.54 GAE/g 57.08 1.36 QE/g, respectively. The DPPH radical scavenging leaf found be 88.23% 0.87%. Besides, profile showed 15 bioactive compounds. Characterization revealed size ranging from 8 nm 34 with average crystallite 27 nm. FTIR important functional groups that responsible reduction stabilization AgNPs. assays, 100 μg/ml AgNPs AgNPs-PE strongly inhibited . tested sprayed on plants controlled environment exhibited nearly 100% survival no observable phytotoxicity. These finding provide a simple baseline control nano bio-control agents without affecting crop health.

Язык: Английский

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Improvement of heat stress tolerance in soybean (Glycine max L), by using conventional and molecular tools

Frontiers in Plant Science, Год журнала: 2022, Номер 13

Опубликована: Сен. 26, 2022

The soybean is a significant legume crop, providing several vital dietary components. Extreme heat stress negatively affects yield and quality, especially at the germination stage. Continuous change in climatic conditions threatening global food supply security. Therefore, it critical need of time to develop heat-tolerant genotypes. Different molecular techniques have been developed improve tolerance soybean, but until now complete genetic mechanism not fully understood. Various methods, like quantitative trait loci (QTL) mapping, engineering, transcription factors (TFs), transcriptome, clustered regularly interspaced short palindromic repeats (CRISPR), are employed incorporate under extreme stress. These significantly improved soybean. Besides this, we can also use specific classical breeding approaches different hormones reduce harmful consequences waves on In future, integrated these tools would bring results developing current review, presented detailed overview improvement highlighted future prospective. Further studies required investigate governing response This information be helpful for focusing improving

Язык: Английский

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Biocatalysis as a Green Approach for Synthesis of Iron Nanoparticles—Batch and Microflow Process Comparison

Catalysts, Год журнала: 2023, Номер 13(1), С. 112 - 112

Опубликована: Янв. 4, 2023

There is a growing need for production of iron particles due to their possible use in numerous systems (e.g., electrical, magnetic, catalytic, biological and others). Although severe reaction conditions heavy solvents are frequently used nanoparticles, green synthesis has arisen as an eco-friendly method that uses catalysts. Various precursors combined with material (such enzymes, herbal extracts, biomass, bacteria or yeasts) contain chemicals from the main secondary metabolism can function catalysts nanoparticles. In this work, batch (“one-pot”) biosynthesis nanoparticles reviewed, well possibilities using microfluidic continuous which could overcome limitations synthesis.

Язык: Английский

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