Exploring Alternative Splicing in Response to Salinity: A Tissue-Level Comparative Analysis Using Arabidopsis thaliana Public Transcriptomic Data DOI Creative Commons
Jesús Hernández-Urrieta, José M. Álvarez, José Antonio O’Brien

и другие.

Plants, Год журнала: 2025, Номер 14(7), С. 1064 - 1064

Опубликована: Март 30, 2025

Increased soil salinity is a major threat to global agriculture and food security, caused mainly by anthropogenic activities changing climatic cycles. Plants responses involve multiple regulatory layers, from transcriptome reprogramming proteomic metabolomic changes. Alternative splicing (AS) plays role in coordinating the response salinity, yet its extent, tissue, condition specificity, remain poorly understood aspects. In this study, we used 52 publicly available RNA-seq datasets of treatment identify differential alternative (DAS) events genes participating stimulus. Our findings reveal that either independently or coordinately, AS can regulate up 20% detected Arabidopsis, with intensity being most determining factor. Moreover, show regulation was highly tissue-specific, roots displaying strong AS-mediated stress responses. Furthermore, cross-stress comparisons showed have core set AS-regulated associated development, functionally distinct sets when comparing salt other stresses, while also conserving relevant condition-specific response. We demonstrate need integrate analysis better understand plant adaptation mechanisms highlight key responses, revealing shared between salt, heat, drought

Язык: Английский

Exploring Alternative Splicing in Response to Salinity: A Tissue-Level Comparative Analysis Using Arabidopsis thaliana Public Transcriptomic Data DOI Creative Commons
Jesús Hernández-Urrieta, José M. Álvarez, José Antonio O’Brien

и другие.

Plants, Год журнала: 2025, Номер 14(7), С. 1064 - 1064

Опубликована: Март 30, 2025

Increased soil salinity is a major threat to global agriculture and food security, caused mainly by anthropogenic activities changing climatic cycles. Plants responses involve multiple regulatory layers, from transcriptome reprogramming proteomic metabolomic changes. Alternative splicing (AS) plays role in coordinating the response salinity, yet its extent, tissue, condition specificity, remain poorly understood aspects. In this study, we used 52 publicly available RNA-seq datasets of treatment identify differential alternative (DAS) events genes participating stimulus. Our findings reveal that either independently or coordinately, AS can regulate up 20% detected Arabidopsis, with intensity being most determining factor. Moreover, show regulation was highly tissue-specific, roots displaying strong AS-mediated stress responses. Furthermore, cross-stress comparisons showed have core set AS-regulated associated development, functionally distinct sets when comparing salt other stresses, while also conserving relevant condition-specific response. We demonstrate need integrate analysis better understand plant adaptation mechanisms highlight key responses, revealing shared between salt, heat, drought

Язык: Английский

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