Genome-Wide Analysis of the EIN3/EIL Transcription Factors in Osmanthus fragrans and Their Stress Response to Azacytidine (AZA) and Ethylene (ETH) Treatment DOI Creative Commons
Dou Pan,

Chun Xu,

W. Ma

и другие.

Horticulturae, Год журнала: 2025, Номер 11(6), С. 572 - 572

Опубликована: Май 23, 2025

Ethylene-insensitive 3/ethylene-insensitive 3-like (EIN3/EIL) transcription factors are central regulators of ethylene signaling and stress adaptation in plants. However, their roles Osmanthus fragrans, a globally cherished ornamental aromatic plant with significant economic value, remain poorly characterized. Here, we identified nine OfEIL genes across eight chromosomes the O. fragrans “Liuye Jingui” genome. Conserved motif analysis revealed core domains (Motif1/2/4/7), promoter cis-elements highlighting hormone-related, stress-related, growth-related regulatory potential. During late flowering stages, six OfEILs (3/4/5/6/7/9) were significantly upregulated. Under 5-azacytidine (AZA, DNA demethylation agent), OfEIL2 OfEIL7 downregulated, whereas ETH treatment activated OfEIL3/7/8/9. Strikingly, exhibited dual roles, correlating strongly natural progression, AZA-induced demethylation, responses. Functional divergence was observed petal senescence, OfEIL2–5 OfEIL7–9 showing stage-specific tissue-specific expression patterns. These results position as key hub integrating epigenetic hormonal signals to modulate floral longevity adaptation. Our study provides first genome-wide characterization EIL family offering critical insights for molecular breeding aimed at enhancing traits environmental resilience this economically species.

Язык: Английский

Mendelian randomization study on the causal relationships among fasting blood glucose, plasma proteins, and squamous cell lung cancer DOI Creative Commons
RongLin Li,

Zhenniu Lei,

Zhao-ke Wen

и другие.

Discover Oncology, Год журнала: 2025, Номер 16(1)

Опубликована: Апрель 22, 2025

Squamous cell lung cancer (SQCLC) represents the second most common subtype of (LC) with characteristics treatment resistance. Plasma proteins often influence levels fasting blood glucose (FBG), consequently impacting LC. However, precise role FBG in this association remains unclear. To investigate causal relationships LC and its subtypes, plasma proteins, SQCLC, as well mediating FBG. Mendelian randomization (MR) analysis was employed to assess associations FBG, using two-step MR approach primary method being Inverse Variance Weighted (IVW). Protein-Protein Interaction (PPI) network utilized identify hub genes causally linked SQCLC. a risk factor for SQCLC (OR: 1.376, 95% CI 1.017-1.862, P = 0.038) but had no significant other subtypes (P > 0.05). Furthermore, 54 < EEF2 K 1.111, 1.015-1.216, 0.023) SSR1 0.546, 0.487-0.613, 0.001) were identified protective respectively. Mediation indicated negative effect relationship between (B - 0.193, 0.312-0.074, 0.001), mediation proportion 44.4%. Our study revealed demonstrated

Язык: Английский

Процитировано

0
Hormone metabolic profiling and transcriptome analysis reveal phytohormone crosstalk and the role of OfERF017 in the flowering and senescence of sweet osmanthus DOI Creative Commons
Xuan Cai,

Xiangling Zeng,

Xiaoqian Wang

и другие.

Horticultural Plant Journal, Год журнала: 2025, Номер unknown

Опубликована: Май 1, 2025

Язык: Английский

Процитировано

0
Genome-Wide Analysis of the EIN3/EIL Transcription Factors in Osmanthus fragrans and Their Stress Response to Azacytidine (AZA) and Ethylene (ETH) Treatment DOI Creative Commons
Dou Pan,

Chun Xu,

W. Ma

и другие.

Horticulturae, Год журнала: 2025, Номер 11(6), С. 572 - 572

Опубликована: Май 23, 2025

Ethylene-insensitive 3/ethylene-insensitive 3-like (EIN3/EIL) transcription factors are central regulators of ethylene signaling and stress adaptation in plants. However, their roles Osmanthus fragrans, a globally cherished ornamental aromatic plant with significant economic value, remain poorly characterized. Here, we identified nine OfEIL genes across eight chromosomes the O. fragrans “Liuye Jingui” genome. Conserved motif analysis revealed core domains (Motif1/2/4/7), promoter cis-elements highlighting hormone-related, stress-related, growth-related regulatory potential. During late flowering stages, six OfEILs (3/4/5/6/7/9) were significantly upregulated. Under 5-azacytidine (AZA, DNA demethylation agent), OfEIL2 OfEIL7 downregulated, whereas ETH treatment activated OfEIL3/7/8/9. Strikingly, exhibited dual roles, correlating strongly natural progression, AZA-induced demethylation, responses. Functional divergence was observed petal senescence, OfEIL2–5 OfEIL7–9 showing stage-specific tissue-specific expression patterns. These results position as key hub integrating epigenetic hormonal signals to modulate floral longevity adaptation. Our study provides first genome-wide characterization EIL family offering critical insights for molecular breeding aimed at enhancing traits environmental resilience this economically species.

Язык: Английский

Процитировано

0