Metabolomics and transcriptomics indicate the changes in medicinal components of Amygdalus mongolica kernels during different developmental stages DOI Creative Commons
Zhenyu Lei, Hong Chang, Song Li

и другие.

Frontiers in Plant Science, Год журнала: 2025, Номер 16

Опубликована: Май 23, 2025

Amygdalus mongolica is a traditional Chinese and Mongolian medicine quite effective in relieving cough eliminating phlegm. In this study, ultra-high performance liquid chromatography-mass spectrometry (UPLC-MS) was used to perform metabolomics analysis, combined with transcriptomic sequencing, study the samples of A. at early, middle late growth stages. A comprehensive analysis conducted systematically investigate dynamic changes developmental trajectories kernel progression across distinct stages, utilizing differential expression pathway enrichment approaches. total 104 significant metabolites were identified different stages: early stage (E), (M), (L). Specifically, 68 36 detected comparisons E vs. M L, respectively. Among them, 29 21 exhibiting up-regulation. comparison, 39 15 demonstrated down-regulation. Transcriptomic 133 differentially expressed genes associated 62 pathways M. Simultaneously, 14 linked 13 L. The accumulation various varied marked increase amino acids during phases, alongside fluctuations levels flavonoid compounds. conclusion, reveals variations content types acid compounds key within relevant kernels throughout Especially, compound advancing stages highlights their substantial medicinal potential. These findings provide foundation for future developing valuable ingredients kernels.

Язык: Английский

Metabolomics and transcriptomics indicate the changes in medicinal components of Amygdalus mongolica kernels during different developmental stages DOI Creative Commons
Zhenyu Lei, Hong Chang, Song Li

и другие.

Frontiers in Plant Science, Год журнала: 2025, Номер 16

Опубликована: Май 23, 2025

Amygdalus mongolica is a traditional Chinese and Mongolian medicine quite effective in relieving cough eliminating phlegm. In this study, ultra-high performance liquid chromatography-mass spectrometry (UPLC-MS) was used to perform metabolomics analysis, combined with transcriptomic sequencing, study the samples of A. at early, middle late growth stages. A comprehensive analysis conducted systematically investigate dynamic changes developmental trajectories kernel progression across distinct stages, utilizing differential expression pathway enrichment approaches. total 104 significant metabolites were identified different stages: early stage (E), (M), (L). Specifically, 68 36 detected comparisons E vs. M L, respectively. Among them, 29 21 exhibiting up-regulation. comparison, 39 15 demonstrated down-regulation. Transcriptomic 133 differentially expressed genes associated 62 pathways M. Simultaneously, 14 linked 13 L. The accumulation various varied marked increase amino acids during phases, alongside fluctuations levels flavonoid compounds. conclusion, reveals variations content types acid compounds key within relevant kernels throughout Especially, compound advancing stages highlights their substantial medicinal potential. These findings provide foundation for future developing valuable ingredients kernels.

Язык: Английский

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