The Role of Complexity Theory in Understanding Brain's Neuron–Glia Interactions

European Journal of Neuroscience, Год журнала: 2025, Номер 61(5)

Опубликована: Март 1, 2025

ABSTRACT Brain information processing complexity is conventionally recognized as derived from neuronal activity, with neurons and their dynamic signalling responsible for the transfer of information. However, brain also contains other non‐neuronal cells, glial which exceed number are involved in processes related coding by neural networks underlying functions. Decisive advances characterization molecular physiological properties cells shed light on active roles neurotransmission physiopathology. This expanded relationship between glia challenges traditional neurobiology highlighting reciprocal influence, where it difficult to determine whether or initiate drive interactions. interplay creates a dilemma, causal hierarchy these two cell types remains unresolved. A philosophical tool, ‘Theory Complexity’ Edgard Morin can help better explain study neuron–glia Morin's proposal useful transform knowledge, order review functions antireductionist pattern. In this manuscript, we will discuss how use ‘retroactive loop’ principle at level, proposing new philosophical‐experimental grid that neuroscientists understanding glia–neuron interactions brain.

Язык: Английский

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Relationships and representations of brain structures, connectivity, dynamics and functions

Progress in Neuro-Psychopharmacology and Biological Psychiatry, Год журнала: 2025, Номер unknown, С. 111332 - 111332

Опубликована: Март 1, 2025

Язык: Английский

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Evaluation of False, Reductionist Part-Whole Relationships in Biochemistry and Its Effect on Health Science Students’ Chemistry-Based Health Literacy

Science & Education, Год журнала: 2025, Номер unknown

Опубликована: Апрель 22, 2025

Язык: Английский

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The Neuroeducation Training of Students in the Degrees of Early Childhood and Primary Education: A Content Analysis of Public Universities in Andalusia

Education Sciences, Год журнала: 2023, Номер 13(10), С. 1006 - 1006

Опубликована: Окт. 4, 2023

Educational neuroscience presents a broad view of what learning is and how when it occurs. Consequently, neuroeducation offers improved strategies for understanding developing the teaching–learning process. It is, therefore, essential that teachers students are trained in neuroeducation, given current knowledge this field. study aims to reflect on training received by undergraduate studying early childhood primary education find out teaching approached universities eight Andalusian provinces. As methodology, content analysis was made, which allowed us transform qualitative data into quantitative data. The categories analysed were “Neuroeducation”, “Metacognition”, “Cognitive processes” “Cognition”. plans 2022/2023 academic year considered. results these showed that, despite relevance educational context, barely addressed subject. This suggested future not enough enable them make most considerations.

Язык: Английский

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Is Ecological Neuroscience Possible?

Interdisciplinary evolution research, Год журнала: 2024, Номер unknown, С. 217 - 245

Опубликована: Янв. 1, 2024

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Reductionism and proxy failure: From neuroscience to target-based drug discovery

Behavioral and Brain Sciences, Год журнала: 2024, Номер 47

Опубликована: Янв. 1, 2024

Abstract Reductionist methodologies reduce phenomena to some of their lower-level components. Researchers gradually shift focus away from observing the actual object study toward investigating and optimizing such proxies. Following reductionism, these proxies progressively diverge further original study. We vividly illustrate this in evolution target-based drug discovery rational phenotypic discovery.

Язык: Английский

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The role of complexity theory in understanding brain's neuron-glia interactions.

Authorea (Authorea), Год журнала: 2024, Номер unknown

Опубликована: Авг. 28, 2024

Brain information processing complexity is conventionally recognized as derived from neuronal activity, with neurons and their dynamic signalling responsible for the transfer of . However, brain also contains other non-neuronal cells, glial which exceed number have been largely ignored, in past, being involved processes related coding by neural networks underlying functions. Nonetheless, decisive advances characterization molecular physiological properties cells shed light on active roles neurotransmission physio-pathology. Thus, order to understand functions we need consider relationship between cells. This expanded glia challenging traditional neurobiology, representing a typical 'chicken egg 'problem. A philosophical tool, 'Theory Complexity' Edgard Morin can help better explain study neuronal- interactions. Morin's proposal useful transform knowledge, review anti-reductionist pattern. In this manuscript, will discuss how use 'retroactive loop' principle at level, proposing new philosophical-experimental grid that neuroscientists understanding glia-neurons interactions brain.

Язык: Английский

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Journal of Multiscale Neuroscience

Journal of Multiscale Neuroscience, Год журнала: 2023, Номер 2(1), С. 221 - 239

Опубликована: Март 30, 2023

There is growing evidence that brain processes involve multiscale overlapping networks and the mapping between such neural cognitive functions many-to-many. So, answer to question what spatiotemporal scales in are most relevant for cognition, action, experience, etc., several inextricably interconnected integrated relevant. also brains embodied agents (people) part of “larger” distributed “bio-psycho-social networks.” One cannot fully appreciate do how they work isolation from these larger multiscale, multi-level, multi-faceted “4E” (embodied, embedded, extended, enactive). Nor can one explain human or action without an understanding. Establishing claims purpose this paper. Section 2 will unpack claim itself best viewed as dynamical, multifunctional, coordinated, networks. Furthermore, individual conscious embedded dynamical 3 argues characterization 4E not terms mechanistic reduction modularity, but contextual emergence. 4 draw key connections emergence related other philosophers neuroscientists. Lastly, conclude reasonably conceived highly non-decomposable contextually emergent systems. In short, people computers.

Язык: Английский

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None

Journal of Multiscale Neuroscience, Год журнала: 2023, Номер 2(1)

Опубликована: Март 30, 2023

There is growing evidence that brain processes involve multiscale overlapping networks and the mapping between such neural cognitive functions many-to-many.So, answer to question what spatiotemporal scales in are most relevant for cognition, action, experience, etc., several inextricably interconnected integrated relevant.There also brains embodied agents (people) part of "larger" distributed "biopsycho-social networks."One cannot fully appreciate do how they work isolation from these larger multiscale, multi-level, multi-faceted "4E" (embodied, embedded, extended, enactive).Nor can one explain human or action without an understanding.Establishing claims purpose this paper.Section 2 will unpack claim itself best viewed as dynamical, multifunctional, coordinated, networks.Furthermore, individual conscious embedded dynamical networks.Section 3 argues characterization 4E not terms mechanistic reduction modularity, but contextual emergence.Section 4 draw key connections emergence related other philosophers neuroscientists.Lastly, Section conclude reasonably conceived highly non-decomposable contextually emergent systems.In short, people computers.

Язык: Английский

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Reductionism and Proxy Failure: From Neuroscience to Target-Based Drug Discovery

Опубликована: Окт. 26, 2023

Reductionist methodologies reduce phenomena to some of their lower-level components. Researchers gradually shift focus away from observing the actual object study toward investigating and optimizing such proxies. Following reductionism, these proxies progressively diverge further original study. We vividly illustrate this in evolution target-based drug discovery rational phenotypic discovery.

Язык: Английский

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