
Acta Psychiatrica Scandinavica, Год журнала: 2024, Номер unknown
Опубликована: Сен. 5, 2024
Abstract Objective Childhood maltreatment is associated with less favourable treatment outcomes pharmacotherapy and psychotherapy for depression. It unknown whether this increased risk of resistance in maltreated individuals extends to electroconvulsive therapy (ECT). Methods This retrospective cohort study included 501 consecutive adult referrals an acute course twice‐weekly ECT unipolar or bipolar depression at academic inpatient centre Ireland between 2016 2024. Retrospectively reported physical sexual childhood were assessed on hospital admission. Response was defined as a score 1 2 remission the Clinical Global Impression – Improvement scale 1–3 days after final session. Logistic regression analyses used examine associations nonresponse nonremission, adjusting covariates. Mediation conducted explore role psychiatric comorbidities, persistent depressive symptoms lasting years more current episode, baseline severity. Results Compared group no maltreatment, had similar odds (adjusted ratio = 1.47, 95% CI 0.85–2.53) but significantly elevated nonremission 3.75, 1.80–7.81). In mediation analysis, presence mediated 7.4% total effect nonremission. Conclusion Individuals exposure may be likely achieve full following ECT.
Язык: Английский