Epidemic after pandemic: Dengue surpasses COVID-19 in number of deaths
Pulmonology,
Год журнала:
2025,
Номер
31(1)
Опубликована: Янв. 7, 2025
Язык: Английский
A serial case report of hospitalized patients with Creutzfeldt-Jakob disease due to coronavirus disease (COVID)-19 in Brazil: A four-year profile
Journal of the Neurological Sciences,
Год журнала:
2025,
Номер
469, С. 123380 - 123380
Опубликована: Янв. 4, 2025
Язык: Английский
Efficacy of Ivermectin, Chloroquine/Hydroxychloroquine, and Azithromycin in Managing COVID-19: A Systematic Review of Phase III Clinical Trials
Biomedicines,
Год журнала:
2024,
Номер
12(10), С. 2206 - 2206
Опубликована: Сен. 27, 2024
During
the
coronavirus
disease
(COVID)-19
pandemic
several
drugs
were
used
to
manage
patients
mainly
those
with
a
severe
phenotype.
Potential
off-label
and
major
concerns
arose
from
their
applicability
managing
health
crisis
highlighting
importance
of
clinical
trials.
In
this
context,
we
described
mechanisms
three
repurposed
[Ivermectin-antiparasitic
drug,
Chloroquine/Hydroxychloroquine-antimalarial
drugs,
Azithromycin-antimicrobial
drug];
and,
based
on
description,
study
evaluated
efficacy
published
in
The
use
these
reflects
period
uncertainty
that
marked
beginning
COVID-19
pandemic,
which
made
them
possible
treatment
for
COVID-19.
Язык: Английский
Evaluation of the case fatality rate in 2 031 309 hospitalised Brazilian patients due to COVID-19: An observational study of the first 3 years of the pandemic in Brazil
BMJ Public Health,
Год журнала:
2025,
Номер
3(1), С. e000724 - e000724
Опубликована: Янв. 1, 2025
Introduction
Since
the
beginning
of
COVID-19
pandemic,
in
Brazil,
there
has
been
a
high
rate
deaths,
mainly
among
those
who
were
hospitalised
due
to
disease
and
needed
intensive
care
units
(ICUs)
mechanical
ventilation
support.
Methods
The
study
evaluated
patients
with
as
well
subgroups
considering
ICU
treatment
received
invasive
an
ICU.
risk
death
was
compared
these
three
groups
adjustments
for
gender,
age,
race
comorbidities.
A
multivariable
analysis
performed
identify
main
predictors
death.
patient
considered
positive
if
they
had
real-time
polymerase
chain
reaction
(RT-PCR)
or
serological
test,
followed
by
notification
form
completed
health
professional,
usually
medical
doctor.
approved
ethics
committee
institution
(Certificate
Presentation
Ethical
Appreciation
n°
67241323.0.0000.5514;
Study
Approval
Technical
Opinion
5.908.611).
Results
2
031
309
individuals
COVID-19.
case
fatality
33.2%
(673
527/2
309).
even
higher
required
(372
031/665
621;
55.9%)
need
support
(240
704/303
505;
79.3%).
In
analysis,
male
sex
(OR=1.14;
95%
CI=1.13–1.15),
older
age
[61
72
years
old
(OR=2.43;
CI=2.41–2.46),
83
85
(OR=4.10;
CI=4.06–4.14)
and+85
(OR=6.98;
CI=6.88–7.07)],
[mixed
(
Pardos
)
(OR=1.33;
CI=1.32–1.34),
Black
people
(OR=1.57;
CI=1.55–1.60)
Indigenous
peoples
(OR=1.82,
CI=1.69–1.97)]
presence
comorbidities
[mainly,
hepatic
disorder
(OR=1.80;
CI=1.73–1.87),
immunosuppressive
CI=1.76–1.84)
kidney
(OR=1.67;
CI=1.64–1.70)]
associated
increased
chance
death,
except
asthma
(OR=0.77;
CI=0.75–0.79).
addition,
all
admitted
COVID-19,
(OR=2.08;
CI=2.06–2.13)
ventilatory
(OR=14.86;
CI=14.66–15.05)
impact
on
outcome.
Conclusion
Although
number
daily
deaths
from
coronavirus
dropped
during
pandemic
our
retrospective
showed
requiring
ICU,
when
using
ventilation,
rest
world.
Язык: Английский
Pulmonary and functional hallmarks after SARS-CoV-2 infection across three WHO severity level-groups: an observational study
Frontiers in Medicine,
Год журнала:
2025,
Номер
12
Опубликована: Апрель 7, 2025
The
manifestations
of
severe
acute
respiratory
syndrome
coronavirus
2
(SARS-CoV-2)
infection
range
from
flu-like
symptoms
to
lung
disease.
consequences
this
inflammatory
process
impact
overall
function,
which
can
be
detected
through
both
short-
long-term
assessments.
This
study
aimed
assess
the
pulmonary
functional
and
structural
characteristics
post-SARS-CoV-2
in
patients
with
mild/moderate,
severe,
critical
clinical
presentations.
An
observational,
analytical,
cross-sectional
was
conducted
between
2020
2022,
including
participants
a
confirmed
diagnosis
disease
(COVID)-19,
mild/moderate
(G1),
(G2),
(G3)
presentations,
all
evaluated
at
least
3
months
after
infection.
Spirometry,
impulse
oscillometry,
fractional
exhaled
nitric
oxide
(FeNO),
chest
computed
tomography,
6-min
walk
test
(6MWT),
hand
grip
strength,
maximum
inspiratory
pressure,
expiratory
pressure
were
assessed.
We
enrolled
210
aged
18-70
years,
32.6%
whom
male,
older
age
observed
G3.
grouped
as
follows:
G1
(42.3%),
G2
(25.7%),
G3
(31.9%).
Percentage
predicted
X5
differed
G2,
being
higher
G1.
percentage
forced
vital
capacity
(FVC)
according
Global
Lung
Function
Initiative
its
z-score
FVC
by
Pereira
lower
compared
volume
1
s
(FEV1)
also
Tiffeneau
(FEV1/FVC)
index
different
among
groups,
increasing
severity.
flow
rate
25-75%
(FEF25-75%)
FeNO
than
Chest
tomography
revealed
presence
interstitial
abnormalities,
associated
muscle
strength
evaluation
showed
an
association
values
G1,
but
no
observed.
6MWT
distance
covered
decreased
severity,
right-hand
Alterations
markers
post-COVID-19
evaluations,
seen
These
findings
highlight
complexity
assessments,
given
sequelae
consequent
impairment
capacity.
Язык: Английский
Supply chain resilience capabilities: an outlook of the Brazilian agri-food sector post Covid-19 pandemic
International Journal of Disaster Risk Reduction,
Год журнала:
2025,
Номер
unknown, С. 105486 - 105486
Опубликована: Апрель 1, 2025
Язык: Английский
Epidemiological profile of patients hospitalized with Crohn’s disease due to severe acute respiratory infection during the COVID-19 pandemic: a 2-year report from Brazil
Frontiers in Medicine,
Год журнала:
2024,
Номер
11
Опубликована: Окт. 23, 2024
Background
and
aims
The
novel
coronavirus-induced
severe
acute
respiratory
syndrome
(COVID-19)
led
to
one
of
the
most
significant
global
pandemics
21st
century,
causing
substantial
challenges
for
healthcare
systems
worldwide,
including
those
in
Brazil.
This
study
aimed
investigate
demographic
clinical
profiles
hospitalized
patients
Brazil
who
had
both
COVID-19
Crohn’s
disease
(CD)
over
a
2-year
period.
Methods
An
epidemiological
analysis
was
conducted
using
data
from
Open-Data-SUS.
focused
on
describing
characteristics,
manifestations,
comorbidities,
hospitalization
details
afflicted
with
due
CD,
aim
predicting
mortality
risk.
Results
states
São
Paulo,
Paraná,
Minas
Gerais
accounted
50%
reported
cases.
affected
racial
group
consisted
individuals
self-declared
as
mixed
race.
Common
comorbidities
included
heart
disease,
diabetes
mellitus,
obesity.
age
25
60
years
old,
particularly
among
CD
ultimately
succumbed
illness.
A
multivariable
identify
following
risk
factors
death:
(a)
presence
neurological
disorder
(OR
=
6.716;
95%
CI
1.954–23.078),
(b)
need
intensive
care
3.348;
1.770–6.335),
(c)
invasive
mechanical
ventilation
59.017;
19.796–175.944).
Conclusion
There
no
discernible
gender-based
prevalence
COVID-19;
however,
race
were
disproportionately
affected.
emerged
vulnerable
group,
high
risks
mortality.
Moreover,
highlights
potential
induce
systemic
pathologies
that
may
result
long-term
degenerative
effects
sequelae.
Язык: Английский
Lifestyles and academic stress among health sciences students at the National University of Chimborazo, Ecuador: a longitudinal study
Frontiers in Public Health,
Год журнала:
2024,
Номер
12
Опубликована: Авг. 12, 2024
Background
The
significant
changes
experienced
by
university
students
in
their
training
are
inherent
to
educational
processes.
Social
isolation
caused
the
COVID-19
pandemic,
online
education
and
reopening
of
higher-education
institutions
produced
substantial
variations
lifestyle
health
sciences
generated
academic
stress
perceived
stress.
This
study
was
conducted
at
National
University
Chimborazo
(UNACH),
a
public
institution
located
Riobamba,
central
Ecuador,
diverse
student's
population
provided
an
ideal
setting
for
examining
interplay
between
stress,
factors,
learning
modalities.
research
focused
on
across
six
programs.
university's
geographical
position
demographic
characteristics
offered
representative
sample
investigating
these
factors
within
context
changing.
Aim
To
compare
students'
lifestyles
two
different
periods:
(1)
during
mandatory
social
confinement
pandemic
with
modality
(T1);
(2)
post-pandemic
period
return
face-to-face
activities
(T2).
Design
An
observational,
analytical,
quantitative,
longitudinal
study.
Participants
Students
from
programs
(Nursing,
Physiotherapy,
Clinical
Laboratory,
Medicine,
Dentistry,
Psychology)
Faculty
Health
Chimborazo-Ecuador
(
n
=
2,237)
participated
voluntarily,
had
one
mean
age
M
21.31
(SD
2.36)
T1
22.94
2.40)
T2.
Non-probability
convenience
sampling
employed
due
accessibility
student
importance
including
maximum
number
relevant
individuals
population.
Methods
following
instruments
were
used:
Nola
Pender's
Lifestyle
Profile
Questionnaire,
Cognitive
Systemic
Inventory
Cohen's
Perceived
Stress
Scale.
Results
In
T2,
reported
high
levels
increased
unhealthy
classrooms.
Additionally,
upon
returning
(T2),
score
applied
responses
Questionnaire
decreased
113.34
23.02)
107.2
29.70;
p
<
0.001).
There
difference
0.001)
[M
66.25
15.66)]
T2
64.00
17.91)].
Conclusions
Upon
classrooms
who
“unhealthy”
increased.
Academic
higher
isolation.
Язык: Английский
A narrative review of the complex panorama regarding chronic neuropathic pain mainly for the psychological issues
Heliyon,
Год журнала:
2024,
Номер
10(19), С. e38282 - e38282
Опубликована: Сен. 21, 2024
Язык: Английский
Assessment of the development of social skills among undergraduate medical students through participation in a socio-educational project during the coronavirus disease (COVID)-19 pandemic: a Brazilian pilot study
BMC Medical Education,
Год журнала:
2024,
Номер
24(1)
Опубликована: Окт. 23, 2024
Coronavirus
disease
(COVID)-19
had
an
impact
on
medical
graduation,
causing
weaknesses
arising
from
social
isolation
and
remote
emergency
teaching,
with
emphasis
deficits
in
the
development
of
non-technical
skills
(soft
skills).
In
this
context,
interaction
between
a
group
students
adolescents
who
develop
activities
at
Center
for
Learning
Mobilization
Citizenship
Campinas/SP,
Brazil,
was
evaluated
about
soft
during
COVID-19
pandemic.
The
observational
study
carried
out
using
electronic
questionnaire
based
Likert
scale
feelings
undergraduate
regarding
participation
project
context
skills.
demonstrated
important
positive
student
socio-educational
skills,
emphasizing
ability
to
deal
adverse
situations,
decision-making,
fear
not
corresponding.
However,
existence
limitations
difficulties
by
revealed,
further
reinforced
challenges
brought
aspect,
voluntary
as
strategy
improve
teaching
these
Язык: Английский