Patient Perceptions of Prenatal Cannabis Use and Implications for Clinicians
Obstetrics and Gynecology,
Год журнала:
2023,
Номер
unknown
Опубликована: Авг. 10, 2023
OBJECTIVE:
To
understand
pregnant
patients'
reasons
for
prenatal
cannabis
use
and
perceptions
of
safety,
desired
undesirable
health
care
experiences,
information
about
secondarily
to
racial
differences
in
these
preferences.
METHODS:
We
conducted
a
qualitative
study
including
18
semi-structured,
race-concordant
virtual
focus
groups
with
individuals
who
self-reported
at
entry
large
integrated
system
Northern
California
from
November
2021
December
2021.
The
included
semi-structured
questions
that
were
recorded,
transcribed,
coded
by
the
research
team.
Thematic
analysis
was
used
analyze
data.
RESULTS:
Overall,
53
participants
included;
30
self-identified,
as
White
23
self-identified
Black.
Participants
averaged
30.3
years
age
(SD
5.2
years)
on
average
20.9
weeks
gestation
enrollment;
69.8%
reported
daily
use,
24.5%
weekly
5.7%
monthly
or
less
entrance
care.
Although
some
quit
early
pregnancy
because
concerns
potential
risks,
many
perceived
lack
scientific
evidence
believed
safe.
Many
preferred
over-the-counter
prescription
medications
treating
mood,
morning
sickness,
pain,
sleep.
valued
open
interactions
obstetricians
acknowledged
their
motivations
they
risks
through
conversations
educational
materials.
Black
participants'
perspectives
generally
similar,
but
few
uniquely
described
bias
related
use.
CONCLUSION:
Pregnant
patients
manage
mood
medical
symptoms,
safer
than
medications.
Obstetrician-initiated,
patient-centered
around
advice
discontinue
during
pregnancy,
exploration
willingness
switch
medically
recommended
interventions
pregnancy-related
symptoms
may
benefit
patients.
Язык: Английский
Exploring Peripartum Cannabis Use Among Young Sexual Minority People: A Qualitative Study
Substance Use & Addiction Journal,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 16, 2025
Introduction:
Young
childbearing
sexual
minority
(SM)
people
are
more
likely
to
use
cannabis
and
have
an
unintended
pregnancy
than
their
heterosexual
peers;
however,
little
is
known
about
perceptions
experiences
of
peripartum
use.
This
qualitative
study
explores
the
relationships
young
pregnant
parenting
SM
with
cannabis,
as
well
feelings
opinions
prenatal
Method:
Participants
who
identified
from
baseline
surveys
YoungMoms
were
recruited
for
semi-structured
interviews
(n
=
13).
Interviews
focused
on
before
during
pregnancy.
Data
analyzed
using
thematic
analysis.
Results:
analysis
revealed
3
key
themes.
described
contextual
adaptivity
use,
discussing
how
changed
based
social
context,
mental
health,
stress
but
was
not
directly
related
sexuality.
Pregnancy
a
potential
turning
point
participants
trying
reduce
or
abstain
pregnancy,
although
some
struggled
do
so
continued
address
symptoms.
Facilitating
factors
reduction
described,
including
focusing
financial
toll,
environment
changes,
access
health-related
guidance,
replacement
hobbies.
Conclusions:
provides
novel
information
public
health
concern
among
population
that
often
overlooked
in
substance
research.
Similar
peers,
may
serve
opportune
time
intervention
consideration
unique
contribute
needed.
Язык: Английский
Brain health Begins Before Birth (B4): A "learning" pregnancy and birth cohort study
Rachel L. Pride,
José Ángel Villarreal,
David Restrepo
и другие.
medRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2025,
Номер
unknown
Опубликована: Март 13, 2025
Abstract
Mental
health
disorders
affect
over
1
billion
people
worldwide,
profoundly
impacting
individuals,
families,
and
the
global
economy.
Risk
for
psychopathology
begins
early
in
life,
with
perinatal
period
representing
a
critical
window
of
vulnerability.
The
Brain
Begins
Before
Birth
(B4)
Study
at
Massachusetts
General
Hospital
(MGH)
is
prospective
birth
cohort
designed
to
identify
modifiable
risk
resilience
factors
influencing
brain
development
child-
adult-onset
psychopathology.
This
study
aims
deeply
phenotype
prenatal
exposures
through
maternal
surveys
administered
multiple
time
points
during
after
pregnancy;
assess
neurodevelopmental
outcomes
first
two
years
life;
triangulate
exposure
outcome
data
underlying
biological
mechanisms.
B4
consists
structured,
remote
covering
psychosocial,
environmental,
health-related
throughout
pregnancy
supplemented
by
medical
record
review.
By
integrating
into
dynamic
learning
model,
advance
field
preventive
psychiatry
identifying
actionable
pathways
intervention,
testing
strategies
real-time,
ultimately
shaping
policies
that
promote
lifelong
mental
wellbeing
from
earliest
stages
development.
Язык: Английский
Changes in Prenatal Cannabis Use and Perceptions During the COVID-19 Pandemic
Drug and Alcohol Dependence Reports,
Год журнала:
2025,
Номер
unknown, С. 100348 - 100348
Опубликована: Май 1, 2025
Язык: Английский
Exploring preferences for different modes of cannabis use during early pregnancy: A qualitative study
Addictive Behaviors,
Год журнала:
2023,
Номер
146, С. 107812 - 107812
Опубликована: Июль 20, 2023
Язык: Английский
Intentions to Use Cannabis Postpartum: A Qualitative Study of Pregnant Individuals Who Used Cannabis During Early Pregnancy
Journal of Women s Health,
Год журнала:
2024,
Номер
33(4), С. 435 - 445
Опубликована: Фев. 26, 2024
To
examine
plans
for
postpartum
cannabis
use
among
pregnant
individuals
who
used
during
early
pregnancy.
Язык: Английский
Trends and Determinants of Neonatal Mortality in Rural Ethiopia
medRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2024,
Номер
unknown
Опубликована: Март 19, 2024
Abstract
Background
Neonatal
mortality
is
a
significant
challenge
that
affects
babies
within
the
first
28
days
of
life.
The
issue
particularly
challenging
for
healthcare
systems
in
developing
countries,
where
interventions
are
required.
Although
there
has
been
decline
neonatal
worldwide,
comprehensive
data
on
patterns
and
contributing
factors
rural
regions
Ethiopia
lacking.
Objective
To
determine
trends
using
2011-2019
DHS
Methods
Ethiopian
demographic
health
survey
(EDHS)
program
conducted
cross-sectional
community-based
study
2011,
2016,
2019.
included
women
who
gave
birth
specified
timeframe
agreed
to
participate.
Sampling
was
done
through
multistage
cluster
approach,
STATA
version
17
used
analyze
data.
Predictor
variables
were
validated
multiple
logistic
regression
analysis.
Weighted
estimates
derive
population-level
statistics
p-value
less
than
0.05
considered
significant.
Results
analyzed
from
22,755
participated
EDHS
surveys
between
2011
rates
decreased
7.5%
6.03%.
Regional
variations
observed,
with
Gambela
Tigrai
having
lowest
rates,
Dire
Dawa
Somali
region
higher
rates.
Factors
like
mother’s
age,
wealth
index,
order,
neonate’s
sex,
presence
twins,
immediate
breastfeeding,
baby’s
size
associated
mortality.
Conclusion
recommendation
Despite
advancements
have
made
decrease
mortality,
remain
challenges
need
be
addressed.
Therefore,
regional
bureaus
should
strengthen
their
strategies
enhance
antenatal
care
(ANC)
visits
promote
delivery
at
facilities.
Язык: Английский
Maternal cannabis use alters excitatory inputs to corticostriatal efferent neurons in rat offspring
bioRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2024,
Номер
unknown
Опубликована: Март 6, 2024
ABSTRACT
With
the
recent
surge
in
cannabis
legalization
across
North
America,
there
is
legitimate
concern
that
rates
of
use
during
pregnancy
will
dramatically
increase
coming
years.
However,
long-term
impacts
prenatal
exposure
(PCE)
on
brain
and
behavior
remain
poorly
understood.
Using
a
model
passive
vapor
exposure,
we
have
previously
shown
PCE
impairs
behavioral
flexibility
an
attentional
set-shifting
task
adult
offspring,
which
orchestrated
part
by
excitatory
inputs
from
medial
prefrontal
cortex
(mPFC)
to
nucleus
accumbens
(NAc).
Given
fundamental
role
these
corticostriatal
coordinating
flexible
reward-seeking
strategies,
used
combination
retrograde
tracing
ex
vivo
electrophysiology
test
hypothesis
maternal
alters
synaptic
intrinsic
membrane
properties
efferent
neurons
exposed
male
female
rat
offspring.
Specifically,
pregnant
dams
were
trained
self-administer
vaporized
(69.7%
THC;
150
mg/ml)
twice
daily
throughout
mating
gestation
offspring
subsequently
injected
with
fluorescent
retrobeads
into
NAc
core
prior
conducting
whole-cell
recordings
spontaneous
inhibitory
post-synaptic
currents
(EPSC
IPSC,
respectively)
retrolabeled
mPFC
adulthood.
Our
results
indicate
increases
frequency
glutamatergic
events
(EPSCs)
NAc-projecting
sex-specific
manner,
drives
changes
(EPSC/IPSC)
ratio,
particularly
females.
Furthermore,
amplitude
phasic
was
reduced
cannabis-exposed
both
sexes,
suggesting
postsynaptic
receptor
function.
Altogether,
data
demonstrate
shifts
balance
excitatory/inhibitory
onto
limited
effects
conductance
females,
resulting
sex
differences
following
self-administration.
These
provide
putative
neurophysiological
mechanisms
mediating
observed
changes,
future
studies
need
if
cannabis-induced
are
causal
deficits
been
documented
Язык: Английский