Symptom experiences and influencing factors in patients undergoing chemotherapy for gastrointestinal cancers: a qualitative study DOI Creative Commons
Xiao‐Ying Huang, Yang Heng,

Yanyan Qiao

и другие.

Frontiers in Psychology, Год журнала: 2024, Номер 15

Опубликована: Май 9, 2024

To explore the symptom experiences and influencing factors of gastrointestinal (GI) cancer patients on chemotherapy (CTX) in China.

Язык: Английский

Zanidatamab for HER2-amplified, unresectable, locally advanced or metastatic biliary tract cancer (HERIZON-BTC-01): a multicentre, single-arm, phase 2b study DOI
James J. Harding, Jia Fan, Do‐Youn Oh

и другие.

The Lancet Oncology, Год журнала: 2023, Номер 24(7), С. 772 - 782

Опубликована: Июнь 2, 2023

Язык: Английский

Процитировано

134

Burden of Gastrointestinal Tumors in Asian Countries, 1990–2021: An Analysis for the Global Burden of Disease Study 2021 DOI Creative Commons

Donglin Jiang,

Yangxue Wu,

Ling Liu

и другие.

Clinical Epidemiology, Год журнала: 2024, Номер Volume 16, С. 587 - 601

Опубликована: Сен. 1, 2024

Gastrointestinal tumors represent a significant component of the cancer burden in Asia. This study aims to evaluate gastrointestinal Asia from 1990 2021 using data Global Burden Disease Study (GBD 2021).

Язык: Английский

Процитировано

9

Burden of digestive system diseases in China and its provinces during 1990–2019: Results of the 2019 Global Disease Burden Study DOI Creative Commons
Zhiyuan Cheng, Tinglu Wang, Yunfei Jiao

и другие.

Chinese Medical Journal, Год журнала: 2024, Номер unknown

Опубликована: Авг. 14, 2024

Evaluating the impact of digestive system diseases is vital for devising effective prevention strategies. However, comprehensive reports on burden in China are lacking. Our study aimed to provide an overview and trends from 1990 2019 its provinces.

Язык: Английский

Процитировано

8

Spatiotemporal Patterns of Esophageal Cancer Burden Attributable to Behavioral, Metabolic, and Dietary Risk Factors From 1990 to 2019: Longitudinal Observational Study DOI Creative Commons
Peng Li, Jing Jing, Wenjun Liu

и другие.

JMIR Public Health and Surveillance, Год журнала: 2023, Номер 9, С. e46051 - e46051

Опубликована: Сен. 5, 2023

Esophageal cancer (EC) is the sixth leading cause of cancer-related burden with distinct regional variations globally. Although EC has decreased, specific reasons for this decline are still unclear.This study aims to uncover spatiotemporal patterns risk-attributable in 204 countries and territories from 1990 2019 so that prevention control strategies can be prioritized worldwide.We extracted deaths, disability-adjusted life years (DALYs), age-standardized mortality rates (ASMRs), DALY (ASDRs) global disease (GBD) 2019, terms behavioral, metabolic, dietary factors by age, sex, geographical location. Average annual percentage change (AAPC) was used assess long-term trends ASMRs ASDRs due risk factors.Between greatest decrease attributed low intake fruits vegetables. An AAPC -2.96 (95% CI -3.28 -2.63) -3.12 -3.44 -2.79) ASMR ASDR attributable a low-fruit diet, while an -3.60 -3.84 -3.36) -3.64 -3.92 -3.35) low-vegetable diet. However, high BMI showed significant increases 0.52 0.29-0.75) 0.42 0.18-0.66) compared decreases other risks AAPC<0 (P<.05). East Asia had largest diets, -11.00 -11.32 -10.67) -11.81 -12.21 -11.41) ASDR, followed Central Asia, whereas Western Sub-Saharan Africa increase BMI, 3.28 3.14-3.42) 3.09 2.96-3.22), respectively. China highest smoking, alcohol use, diets. Between there chewing tobacco, diets most countries, wherein BMI.Our shows smoking consumption vegetables shown recently. The patterns, future studies should focus on upward trend BMI.

Язык: Английский

Процитировано

12

The global incident gastrointestinal cancers attributable to suboptimal diets from 1990 to 2018 DOI
Yiting Li, Jia Xing, Caiyu Li

и другие.

Gastroenterology, Год журнала: 2024, Номер 167(6), С. 1141 - 1151

Опубликована: Июль 15, 2024

Язык: Английский

Процитировано

5

Short-term outcomes and quality of life of esophagogastrostomy versus the double-tract reconstruction after laparoscopic proximal gastrectomy DOI Creative Commons

Yong Sun,

Chao Chen, Lei Hou

и другие.

BMC Cancer, Год журнала: 2024, Номер 24(1)

Опубликована: Окт. 28, 2024

There is no optimal reconstruction technique after proximal gastrectomy. The esophagogastrostomy (EG) a rather simple procedure technically, but the incidences of reflux esophagitis and anastomotic stricture are higher. While double-tract (DTR) can lessen postoperative esophagitis, it technically complex with long operation time. purpose this study was to evaluate quality life (QoL) short-term outcomes two techniques. We retrospectively collected consecutive patients upper-third gastric adenocarcinoma esophagogastric junction (AEG) at our center between 2019 June 2023 May. Patients who underwent laparoscopic gastrectomy (LPG) EG or DTR were included in study. A comparison made clinical pathological characteristics their surgical parameters, complications, its 1-year QoL groups. groups assessed by Visick grading, European Organization for Research Treatment Cancer (EORTC) QLQ-C30 EORTC QLQ-STO22 scales 1 year operation. nutritional status evaluated BMI, hemoglobin serum albumin. AII qualified divided group (n = 63) 93). Compared group, blood loss volume more (p 0.001). significant differences duration, number lymph nodes dissected, length stay groups(p > 0.05). No statistical observed terms incidence early complications Clavien-Dindo classification as well(p After one year, grade better than 0.040). multivariable logistic regression analysis showed only independent risk factor method. According questionnaire, had global health status(p 0.001) complained less about nausea vomiting(p 0.033), appetite 0.022). 0.030) based on questionnaire. multiple linear revealed that method, age relationship score. Regarding status, BMI both decreased operation, decline value lower statistically difference change Our findings suggest possible skilled surgeons achieve minimal without significantly increasing duration when performing DRT, which does not raise risk. In anti-reflux, maintenance, follow-up reveal superior EG, deserve further research promotion.

Язык: Английский

Процитировано

4

Short-term outcomes of laparoscopic D2 lymphadenectomy versus D2 lymphadenectomy plus complete mesogastric excision in distal gastric cancer patients with high body mass index DOI Creative Commons

Yong Sun,

Lei Hou, Enhong Zhao

и другие.

BMC Cancer, Год журнала: 2025, Номер 25(1)

Опубликована: Фев. 23, 2025

The technical challenges and safety issues involving laparoscopic D2 lymphadenectomy plus complete mesogastric excision (D2 + CME) for high body mass index (BMI) patients are still unknown. This study was conducted to compare the short-term outcomes of CME in distal gastric cancer different BMI status. We retrospectively analyzed data with who underwent laparoscopic-assisted gastrectomy (LADG) at our center between 2019 June 2023 September. Patients traditional were divided into group, while undergoing group. In each further subdivided based on their group (H-BMI, ≥ 25) normal (N-BMI, BMI<25) A comparison made characteristics two subgroups, respectively. Propensity score matching (PSM) 1:1 ratio performed assess groups. AII qualified (n = 329) 261). subgroup analysis early surgical had longer surgery time (p 0.007), more blood loss 0.006) first flatus 0.001), compared subgroup. Conversely, significant differences not observed subgroups(p > 0.05). PSM yielded 44 comparable baseline B Compared received shorter time(p<0.001), less loss(p 0.004), retrieved lymph nodes (LNs) 0.016). No statistical terms time, pT stage, pN pathological stage(pStage), vascular invasion, postoperative complications, or hospital stay(p Our findings suggest status a impact results conventional lymphadenectomy. However, unaffected by BMI. addition, benefit from outcomes. Laparoscopic is recommended technique BMI, which deserves promotion.

Язык: Английский

Процитировано

0

Southeast Asia burden and trend of Gastrointestinal tract cancers from 1990 to 2021 and its prediction to 2050: findings from the Global Burden of Disease Study 2021 DOI Creative Commons

Duanyu Wang,

Minghao Tan,

Pengkhun Nov

и другие.

International Journal of Colorectal Disease, Год журнала: 2025, Номер 40(1)

Опубликована: Март 8, 2025

The burden of disease associated with gastrointestinal (GI) tract cancer in Southeast Asia has changed significantly recent years. This study analyzes data from the Global Burden Disease Study (GBD)-2021 to examine trends GI cancers 1990 2021, identifies key risk factors, and predicts future trends. First, this obtained on by age, sex, etiology, incidence, prevalence, deaths, disability-adjusted life years (DALYs), factor GBD-2021 focused 2021. Secondly, also examined temporal trend subtype-specific 2021 using linear regression modeling calculate estimated annual percentage change (EAPC) values. autoregressive integrated moving average (ARIMA) model was used project 2022 2050. Finally, factors for different etiologies were analyzed. In number DALYs, prevalence cases about 216,074, 5,955,050, 258,629, 686,835, respectively, colorectal (CRC) most severe disease. Between deaths DALYs CRC pancreatic (PC) corresponding age-standardized rates (ASRs) showed a significant upward trend, fastest growth being PC. total esophageal (EC), gastric (GC), liver (LC), gallbladder biliary (GBTC) cancer-related increased, but declined significantly. Predictive suggest that death rate (ASDR), ASR incidence (ASIR), (ASPR) will continue decline EC, GC, LC, pronounced declines, especially GC. Overall, ASRs rise CRC, PC, GBTC cancers. ASDRs are greatest among those over 90 age. is greater men than women, gender-induced difference LC. While various types experiencing both increases overall remains significant, expected coming To alleviate impact cancers, public health professionals policymakers must proactively develop adapt prevention control strategies, ensuring they aligned shifting evolving each type tumor.

Язык: Английский

Процитировано

0

Trends, patterns, and risk factors of esophageal cancer mortality in China, 2008–2021: A national mortality Surveillance System data analysis DOI Creative Commons
Yunfei Jiao, Tinglu Wang, Lin Fu

и другие.

Journal of Advanced Research, Год журнала: 2025, Номер unknown

Опубликована: Май 1, 2025

Язык: Английский

Процитировано

0

Global, Regional and National Burden of Stomach Cancer and Its Prediction in 25 Years: A Cross-Sectional Study of the Global Burden of Disease Study 2021 DOI
Xinyan Li, Qing Li, Y. D. Yang

и другие.

British Journal of Hospital Medicine, Год журнала: 2025, Номер 86(5), С. 1 - 21

Опубликована: Май 20, 2025

Aims/Background Given the tremendous threat of stomach cancer (SC) to global public health, detailed information and dynamic updates on SC health burden are needed mitigate repercussions. In this article, we present a systematic analysis trends using data from Global Burden Disease (GBD) Study 2021, aiming provide insights for forming effective management prevention strategies. Methods Stomach incidence, prevalence, mortality, disability-adjusted life years (DALYs) corresponding age-standardized rates (ASRs) were estimated. Then, disease analyzed estimated annual percentage changes (EAPC). Lastly, made unique attempt use two powerful versatile techniques, autoregressive integrated moving average (ARIMA) exponential smoothing (ES) models, more comprehensive accurate forecasts future in burden. Results Despite steady decreasing trend rates, total numbers deaths all increased 1990 2021. Subgroup demonstrated great disparities different age gender groups, sociodemographic index (SDI) quintiles, GBD regions countries. Both ARIMA ES models persistent rise cases concurrent decline ASRs, with being pronounced males. Conclusion Since is already significant issue globally, it expected that will continue future. Therefore, coordinated efforts implement screening projects, consolidate preventive measures formulate targeted treatments alleviate

Язык: Английский

Процитировано

0